Molecular Architecture and Assembly of the Eukaryotic Proteasome

Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity

(2012) Eva M. Huber et al.   CELL

Structural Basis for Specific Recognition of Rpt1p, an ATPase Subunit of 26 S Proteasome, by Proteasome-dedicated Chaperone Hsm3p

(2012) Kenji Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stable Incorporation of ATPase Subunits into 19 S Regulatory Particle of Human Proteasome Requires Nucleotide Binding and C-terminal Tails

(2012) Seung-Hoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a Proteasome Pba1-Pba2 Complex

(2012) Beth M. Stadtmueller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Archaeal Proteasome Is Regulated by a Network of AAA ATPases

(2012) Dara Forouzan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Asymmetries of Proteasome Translocase Pore

(2012) Jenny Erales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Model of the Human 26S Proteasome

(2012) Paula C.A. da Fonseca et al.   MOLECULAR CELL

Destruction deconstructed

(2012) Geng Tian et al.   NATURE

Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy

(2012) E. Sakata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly

(2012) M.-B. Barrault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach

(2012) K. Lasker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Near-atomic resolution structural model of the yeast 26S proteasome

(2012) F. Beck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the Cdc48bullet20S Proteasome as an Ancient AAA+ Proteolytic Machine

(2012) D. Barthelme et al.   SCIENCE

The Structure of the 26S Proteasome Subunit Rpn2 Reveals Its PC Repeat Domain as a Closed Toroid of Two Concentric α-Helical Rings

(2012) Jun He et al.   STRUCTURE

A small-molecule inhibitor of deubiquitinating enzyme USP14 inhibits Dengue virus replication

(2012) Dilip K. Nag et al.   VIRUS RESEARCH

AAA+ Proteases: ATP-Fueled Machines of Protein Destruction

(2011) Robert T. Sauer et al.   Annual Review of Biochemistry

Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1

(2011) Tara A Gomez et al.   BMC BIOLOGY

ATP Binds to Proteasomal ATPases in Pairs with Distinct Functional Effects, Implying an Ordered Reaction Cycle

(2011) David M. Smith et al.   CELL

Order of the Proteasomal ATPases and Eukaryotic Proteasome Assembly

(2011) Robert J. Tomko et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Blm10 Protein Promotes Proteasomal Substrate Turnover by an Active Gating Mechanism

(2011) Thomas Dange et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Defects in the Regulatory Particle-Core Particle Interface of the Proteasome Induce a Novel Proteasome Stress Response

(2011) Soyeon Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Rpt5 Protein Interactions with the Core Particle and Nas2 Protein Causes the Formation of Faulty Proteasomes That Are Inhibited by Ecm29 Protein

(2011) Stella Yu-Chien Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome

(2011) Zanlin Yu et al.   MOLECULAR BIOLOGY OF THE CELL

Proteasome Activators

(2011) Beth M. Stadtmueller et al.   MOLECULAR CELL

Incorporation of the Rpn12 Subunit Couples Completion of Proteasome Regulatory Particle Lid Assembly to Lid-Base Joining

(2011) Robert J. Tomko et al.   MOLECULAR CELL

A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding

(2011) Andrew R Kusmierczyk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together

(2011) G. R. Pathare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissection of the assembly pathway of the proteasome lid in Saccharomyces cerevisiae

(2010) Keisuke Fukunaga et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Crystal Structure of Yeast Rpn14, a Chaperone of the 19 S Regulatory Particle of the Proteasome

(2010) Sangwoo Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components

(2010) Carlos Gorbea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12

(2010) Christiane Riedinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a Blm10 Complex Reveals Common Mechanisms for Proteasome Binding and Gate Opening

(2010) Kianoush Sadre-Bazzaz et al.   MOLECULAR CELL

Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells

(2010) Senthil K. Radhakrishnan et al.   MOLECULAR CELL

Ecm29 Fulfils Quality Control Functions in Proteasome Assembly

(2010) Andrea Lehmann et al.   MOLECULAR CELL

Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2

(2010) Xiang Chen et al.   MOLECULAR CELL

Heterohexameric Ring Arrangement of the Eukaryotic Proteasomal ATPases: Implications for Proteasome Structure and Assembly

(2010) Robert J. Tomko et al.   MOLECULAR CELL

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

(2010) Byung-Hoon Lee et al.   NATURE

Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution

(2010) S. Bohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome

(2009) Daniel Finley   Annual Review of Biochemistry

An atomic model AAA-ATPase/20S core particle sub-complex of the 26S proteasome

(2009) Friedrich Förster et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multiple Proteasome-Interacting Proteins Assist the Assembly of the Yeast 19S Regulatory Particle

(2009) Yasushi Saeki et al.   CELL

Multiple Assembly Chaperones Govern Biogenesis of the Proteasome Regulatory Particle Base

(2009) Minoru Funakoshi et al.   CELL

Assembly Pathway of the Mammalian Proteasome Base Subcomplex Is Mediated by Multiple Specific Chaperones

(2009) Takeumi Kaneko et al.   CELL

Catalytic Mechanism and Assembly of the Proteasome

(2009) António J. Marques et al.   CHEMICAL REVIEWS

Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome–ATPase interactions

(2009) Yadong Yu et al.   EMBO JOURNAL

Subcomplexes of PA700, the 19 S Regulator of the 26 S Proteasome, Reveal Relative Roles of AAA Subunits in 26 S Proteasome Assembly and Activation and ATPase Activity

(2009) David Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators

(2009) Beth M. Stadtmueller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron Microscopic Evidence in Support of α-Solenoid Models of Proteasomal Subunits Rpn1 and Rpn2

(2009) Grégory Effantin et al.   JOURNAL OF MOLECULAR BIOLOGY

The 20S Proteasome as an Assembly Platform for the 19S Regulatory Complex

(2009) Klavs B. Hendil et al.   JOURNAL OF MOLECULAR BIOLOGY

PCI Complexes: Beyond the Proteasome, CSN, and eIF3 Troika

(2009) Elah Pick et al.   MOLECULAR CELL

Structure and Activity of the N-Terminal Substrate Recognition Domains in Proteasomal ATPases

(2009) Sergej Djuranovic et al.   MOLECULAR CELL

Together, Rpn10 and Dsk2 Can Serve as a Polyubiquitin Chain-Length Sensor

(2009) Daoning Zhang et al.   MOLECULAR CELL

Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13

(2009) Naixia Zhang et al.   MOLECULAR CELL

Hsm3/S5b Participates in the Assembly Pathway of the 19S Regulatory Particle of the Proteasome

(2009) Benoît Le Tallec et al.   MOLECULAR CELL

Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii

(2009) Fan Zhang et al.   MOLECULAR CELL

Mechanism of Substrate Unfolding and Translocation by the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii

(2009) Fan Zhang et al.   MOLECULAR CELL

Chaperone-mediated pathway of proteasome regulatory particle assembly

(2009) Jeroen Roelofs et al.   NATURE

Hexameric assembly of the proteasomal ATPases is templated through their C termini

(2009) Soyeon Park et al.   NATURE

Insights into the molecular architecture of the 26S proteasome

(2009) S. Nickell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Tetrahedral Transition State at the Active Sites of the 20S Proteasome Is Coupled to Opening of the α-Ring Channel

(2009) Pawel A. Osmulski et al.   STRUCTURE

Some assembly required: dedicated chaperones in eukaryotic proteasome biogenesis

(2008) Andrew R. Kusmierczyk et al.   BIOLOGICAL CHEMISTRY

Dissecting β-ring assembly pathway of the mammalian 20S proteasome

(2008) Yuko Hirano et al.   EMBO JOURNAL

Mechanism of Gate Opening in the 20S Proteasome by the Proteasomal ATPases

(2008) Julius Rabl et al.   MOLECULAR CELL

Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction

(2008) Patrick Schreiner et al.   NATURE

Proteasome subunit Rpn13 is a novel ubiquitin receptor

(2008) Koraljka Husnjak et al.   NATURE

Diversity of degradation signals in the ubiquitin–proteasome system

(2008) Tommer Ravid et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes

(2008) Hideki Yashiroda et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The central unit within the 19S regulatory particle of the proteasome

(2008) Rina Rosenzweig et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A multimeric assembly factor controls the formation of alternative 20S proteasomes

(2008) Andrew R Kusmierczyk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY