Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Signaling Regulates Mitochondrial Biogenesis and Respiration via Estrogen-related Receptor α (ERRα)

Oxidative stress induced by P2X7 receptor stimulation in murine macrophages is mediated by c-Src/Pyk2 and ERK1/2

(2013) Guadalupe Martel-Gallegos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Ras-induced ROS upregulation affecting cell proliferation is connected with cell type-specific alterations of HSF1/SESN3/p21Cip1/WAF1pathways

(2013) Maria Zamkova et al.   CELL CYCLE

Recruitment of Nox4 to a Plasma Membrane Scaffold Is Required for Localized Reactive Oxygen Species Generation and Sustained Src Activation in Response to Insulin-like Growth Factor-I

(2013) Gang Xi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ROS production as a common mechanism of ENaC regulation by EGF, insulin, and IGF-1

(2012) Daria V. Ilatovskaya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Reactive Oxygen Species: The Achilles' Heel of Cancer Cells?

(2012) Xiaojiang Cui   ANTIOXIDANTS & REDOX SIGNALING

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Is cancer a metabolic rebellion against host aging? In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism

(2012) Adam Ertel et al.   CELL CYCLE

Mitochondria “fuel” breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells

(2012) Federica Sotgia et al.   CELL CYCLE

Dissecting the different biological effects of oncogenic Ras isoforms in cancer cell lines: Could stimulation of oxidative stress be the one more weapon of H-Ras?

(2012) Maurizio Bellavia et al.   MEDICAL HYPOTHESES

The anti-motility signaling mechanism of TGF 3 that controls cell traffic during skin wound healing

(2012) A. Han et al.   Biology Open

The Metabolic Regulator ERRα, a Downstream Target of HER2/IGF-1R, as a Therapeutic Target in Breast Cancer

(2011) Ching-yi Chang et al.   CANCER CELL

The Akt kinases: Isoform specificity in metabolism and cancer

(2011) Eva Gonzalez et al.   CELL CYCLE

Adaptive Basal Phosphorylation of eIF2  Is Responsible for Resistance to Cellular Stress-Induced Cell Death in Pten-Null Hepatocytes

(2011) N. Zeng et al.   MOLECULAR CANCER RESEARCH

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

(2011) Judith Y. Altarejos et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid

(2011) Jia Yao et al.   NEUROBIOLOGY OF AGING

A Unique Metastasis Gene Signature Enables Prediction of Tumor Relapse in Early-Stage Hepatocellular Carcinoma Patients

(2010) S. Roessler et al.   CANCER RESEARCH

Identification of a Cholangiocarcinoma-Like Gene Expression Trait in Hepatocellular Carcinoma

(2010) H. G. Woo et al.   CANCER RESEARCH

Expansion of Hepatic Tumor Progenitor Cells in Pten-Null Mice Requires Liver Injury and Is Reversed by Loss of AKT2

(2010) Vivian A. Galicia et al.   GASTROENTEROLOGY

Mitochondrial mutations in hepatocellular carcinomas and fibrolamellar carcinomas

(2010) Perumal Vivekanandan et al.   MODERN PATHOLOGY

Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation

(2010) V. Fogal et al.   MOLECULAR AND CELLULAR BIOLOGY

The causes of cancer revisited: “Mitochondrial malignancy” and ROS-induced oncogenic transformation – Why mitochondria are targets for cancer therapy

(2010) Stephen J. Ralph et al.   MOLECULAR ASPECTS OF MEDICINE

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

(2010) F. Weinberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma

(2009) Y. Hoshida et al.   CANCER RESEARCH

Accelerated Postnatal Growth Increases Lipogenic Gene Expression and Adipocyte Size in Low-Birth Weight Mice

(2009) E. Isganaitis et al.   DIABETES

Tumor suppressors and cell metabolism: a recipe for cancer growth

(2009) R. G. Jones et al.   GENES & DEVELOPMENT

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma

(2008) D. Y. Chiang et al.   CANCER RESEARCH

PI3K Enters Beta-Testing

(2008) Adam J. Shaywitz et al.   Cell Metabolism

Liver diseases and metabolic syndrome

(2008) Sumio Watanabe et al.   JOURNAL OF GASTROENTEROLOGY

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

ERRα: a metabolic function for the oldest orphan

(2008) Josep A. Villena et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Phosphorylation-Dependent Sumoylation Regulates Estrogen-Related Receptor-α and -γ Transcriptional Activity through a Synergy Control Motif

(2007) Annie M. Tremblay et al.   MOLECULAR ENDOCRINOLOGY