Mammalian Target of Rapamycin (mTOR) Inhibition with Rapamycin Improves Cardiac Function in Type 2 Diabetic Mice
出版年份 2013 全文链接
标题
Mammalian Target of Rapamycin (mTOR) Inhibition with Rapamycin Improves Cardiac Function in Type 2 Diabetic Mice
作者
关键词
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出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 7, Pages 4145-4160
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2013-12-27
DOI
10.1074/jbc.m113.521062
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity
- (2013) Debapriya Dutta et al. Autophagy
- Mechanistic Target of Rapamycin Complex 2 Protects the Heart From Ischemic Damage
- (2013) Mirko Völkers et al. CIRCULATION
- Role of microangiopathy in diabetic cardiomyopathy
- (2013) Adriana Adameova et al. HEART FAILURE REVIEWS
- Altered regional cardiac wall mechanics are associated with differential cardiomyocyte calcium handling due to nebulette mutations in preclinical inherited dilated cardiomyopathy
- (2013) K. Maiellaro-Rafferty et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice
- (2013) Andrea Stöhr et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics
- (2013) M. A. Schroeder et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diabetic cardiomyopathy: Myth or reality?
- (2012) Laura Ernande et al. Archives of Cardiovascular Diseases
- Chronic treatment with long acting phosphodiesterase-5 inhibitor tadalafil alters proteomic changes associated with cytoskeletal rearrangement and redox regulation in Type 2 diabetic hearts
- (2012) Saisudha Koka et al. BASIC RESEARCH IN CARDIOLOGY
- Carbonic anhydrase II promotes cardiomyocyte hypertrophy
- (2012) Brittany F. Brown et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Mammalian target of rapamycin signaling in diabetic cardiovascular disease
- (2012) Zhao Chong et al. Cardiovascular Diabetology
- Myocardial insulin resistance, metabolic stress and autophagy in diabetes
- (2012) Kimberley M Mellor et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Rapamycin Reduces Reactive Oxygen Species in Cultured Human Corneal Endothelial Cells
- (2012) Young Joo Shin et al. CURRENT EYE RESEARCH
- Rapamycin protects against myocardial ischemia–reperfusion injury through JAK2–STAT3 signaling pathway
- (2012) Anindita Das et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- A unifying model for mTORC1-mediated regulation of mRNA translation
- (2012) Carson C. Thoreen et al. NATURE
- Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
- (2012) D. W. Lamming et al. SCIENCE
- Macrovascular Effects and Safety Issues of Therapies for Type 2 Diabetes
- (2011) Jorge Plutzky AMERICAN JOURNAL OF CARDIOLOGY
- Rapamycin inhibits hydrogen peroxide-induced loss of vascular contractility
- (2011) Ge Gao et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Autophagy anomalies in the diabetic myocardium
- (2011) Kimberley M. Mellor et al. Autophagy
- Proteomic analysis of mitochondrial proteins in a mouse model of type 2 diabetes
- (2011) M.F. Essop et al. Cardiovascular Journal of Africa
- Oxidative stress and diabetes mellitus
- (2011) Hui Yang et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Long-term outcome after sirolimus-eluting stents versus bare metal stents in patients with Diabetes mellitus: a patient-level meta-analysis of randomized trials
- (2011) Antoinette de Waha et al. Clinical Research in Cardiology
- Absence of altered autophagy after myocardial ischemia in diabetic compared with nondiabetic mice
- (2011) Christopher J. French et al. CORONARY ARTERY DISEASE
- Changing pattern of gene expression is associated with ventricular myocyte dysfunction and altered mechanisms of Ca2+signalling in young type 2 Zucker diabetic fatty rat heart
- (2011) F. C. Howarth et al. EXPERIMENTAL PHYSIOLOGY
- Chronic Inhibition of Pyruvate Dehydrogenase in Heart Triggers an Adaptive Metabolic Response
- (2011) Kari T. Chambers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of protein targets underlying dietary nitrate-induced protection against doxorubicin cardiotoxicity
- (2011) Lei Xi et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
- (2011) Ken Inoki et al. JOURNAL OF CLINICAL INVESTIGATION
- Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice
- (2011) Kimberley M. Mellor et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Increased CD36 expression in middle-aged mice contributes to obesity-related cardiac hypertrophy in the absence of cardiac dysfunction
- (2011) Miranda M. Y. Sung et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Hyperactive S6K1 Mediates Oxidative Stress and Endothelial Dysfunction in Aging: Inhibition by Resveratrol
- (2011) Angana G. Rajapakse et al. PLoS One
- The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile
- (2011) B. T. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- AICAR treatment for 14 days normalizes obesity-induced dysregulation of TORC1 signaling and translational capacity in fasted skeletal muscle
- (2010) Joshua C. Drake et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Deficiency in AMP-activated protein kinase exaggerates high fat diet-induced cardiac hypertrophy and contractile dysfunction
- (2010) Subat Turdi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Nebulette Mutations Are Associated With Dilated Cardiomyopathy and Endocardial Fibroelastosis
- (2010) Enkhsaikhan Purevjav et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance
- (2010) S. C. Ranieri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rapamycin inhibits mTORC1, but not completely
- (2009) Carson C. Thoreen et al. Autophagy
- The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential
- (2009) Hiroyuki Mori et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nonsense-Mediated mRNA Decay and Ubiquitin–Proteasome System Regulate Cardiac Myosin-Binding Protein C Mutant Levels in Cardiomyopathic Mice
- (2009) Nicolas Vignier et al. CIRCULATION RESEARCH
- An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
- (2009) Carson C. Thoreen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting the mTOR Signaling Network for Cancer Therapy
- (2009) Funda Meric-Bernstam et al. JOURNAL OF CLINICAL ONCOLOGY
- Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes
- (2008) Shigemiki Omiya et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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