Distinct Roles of the Phosphatidate Phosphatases Lipin 1 and 2 during Adipogenesis and Lipid Droplet Biogenesis in 3T3-L1 Cells

Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets

(2013) Florian Wilfling et al.   DEVELOPMENTAL CELL

Lipid Droplets and Cellular Lipid Metabolism

(2012) Tobias C. Walther et al.   Annual Review of Biochemistry

Controlling the size of lipid droplets: lipid and protein factors

(2012) Hongyuan Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression

(2012) I. Mylonis et al.   JOURNAL OF CELL SCIENCE

Cell Autonomous Lipin 1 Function Is Essential for Development and Maintenance of White and Brown Adipose Tissue

(2012) K. Nadra et al.   MOLECULAR AND CELLULAR BIOLOGY

Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum

(2012) J. R. Dwyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucose-6-phosphate isomerase deficiency results in mTOR activation, failed translocation of lipin 1α to the nucleus and hypersensitivity to glucose: Implications for the inherited glycolytic disease

(2011) Jorge F. Haller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

Lipin-1γ isoform is a novel lipid droplet-associated protein highly expressed in the brain

(2011) Huajin Wang et al.   FEBS LETTERS

A Hypomorphic Mutation inLpin1Induces Progressively Improving Neuropathy and Lipodystrophy in the Rat

(2011) Joram D. Mul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipin-1 Phosphatidic Phosphatase Activity Modulates Phosphatidate Levels to Promote Peroxisome Proliferator-activated Receptor γ (PPARγ) Gene Expression during Adipogenesis

(2011) Peixiang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidate Phosphatase Activity Plays Key Role in Protection against Fatty Acid-induced Toxicity in Yeast

(2011) Stylianos Fakas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets

(2011) Oludotun Adeyo et al.   JOURNAL OF CELL BIOLOGY

Subcellular Localization and Role of Lipin-1 in Human Macrophages

(2011) M. Valdearcos et al.   JOURNAL OF IMMUNOLOGY

Lysophosphatidic Acid Activates Peroxisome Proliferator Activated Receptor-γ in CHO Cells That Over-Express Glycerol 3-Phosphate Acyltransferase-1

(2011) Cliona M. Stapleton et al.   PLoS One

Characterization of the HumanLPIN1-encoded Phosphatidate Phosphatase Isoforms

(2010) Gil-Soo Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipin 1 Represses NFATc4 Transcriptional Activity in Adipocytes To Inhibit Secretion of Inflammatory Factors

(2010) H. B. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphatidate degradation: Phosphatidate phosphatases (lipins) and lipid phosphate phosphatases

(2009) David N. Brindley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipin 2 Is a Liver-enriched Phosphatidate Phosphohydrolase Enzyme That Is Dynamically Regulated by Fasting and Obesity in Mice

(2009) Matthew C. Gropler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enzymatic measurement of phosphatidic acid in cultured cells

(2009) Shin-ya Morita et al.   JOURNAL OF LIPID RESEARCH

Sumoylation Regulates Nuclear Localization of Lipin-1α in Neuronal Cells

(2009) Guang-Hui Liu et al.   PLoS One

Phosphatidic acid mediates demyelination in Lpin1 mutant mice

(2008) K. Nadra et al.   GENES & DEVELOPMENT

Temporal and Spatial Regulation of the Phosphatidate Phosphatases Lipin 1 and 2

(2008) Neil Grimsey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fat-specific Protein 27 Regulates Storage of Triacylglycerol

(2008) Pernille Keller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipin1 Is a Key Factor for the Maturation and Maintenance of Adipocytes in the Regulatory Network with CCAAT/Enhancer-binding Protein α and Peroxisome Proliferator-activated Receptor γ2

(2008) Yoo-Kyung Koh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The level and compartmentalization of phosphatidate phosphatase-1 (lipin-1) control the assembly and secretion of hepatic VLDL

(2008) Maroun Bou Khalil et al.   JOURNAL OF LIPID RESEARCH