Lipin-1 Phosphatidic Phosphatase Activity Modulates Phosphatidate Levels to Promote Peroxisome Proliferator-activated Receptor γ (PPARγ) Gene Expression during Adipogenesis

TLE3 Is a Dual-Function Transcriptional Coregulator of Adipogenesis

(2011) Claudio J. Villanueva et al.   Cell Metabolism

piRNA-Associated Germline Nuage Formation and Spermatogenesis Require MitoPLD Profusogenic Mitochondrial-Surface Lipid Signaling

(2011) Huiyan Huang et al.   DEVELOPMENTAL CELL

A Hypomorphic Mutation inLpin1Induces Progressively Improving Neuropathy and Lipodystrophy in the Rat

(2011) Joram D. Mul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidate Phosphatase Activity Plays Key Role in Protection against Fatty Acid-induced Toxicity in Yeast

(2011) Stylianos Fakas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipogenesis at a glance

(2011) C. E. Lowe et al.   JOURNAL OF CELL SCIENCE

Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis

(2011) Mayurranjan S. Mitra et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Impact of Obesity on Cardiovascular Disease

(2011) Kerstyn C. Zalesin et al.   MEDICAL CLINICS OF NORTH AMERICA

Lipin Is a Central Regulator of Adipose Tissue Development and Function in Drosophila melanogaster

(2011) R. Ugrankar et al.   MOLECULAR AND CELLULAR BIOLOGY

Lysophosphatidic Acid Activates Peroxisome Proliferator Activated Receptor-γ in CHO Cells That Over-Express Glycerol 3-Phosphate Acyltransferase-1

(2011) Cliona M. Stapleton et al.   PLoS One

Lipins: Multifunctional Lipid Metabolism Proteins

(2010) Lauren S. Csaki et al.   Annual Review of Nutrition

Lipodystrophy: metabolic insights from a rare disorder

(2010) Isabel Huang-Doran et al.   JOURNAL OF ENDOCRINOLOGY

GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis

(2010) Dandan Shan et al.   JOURNAL OF LIPID RESEARCH

Lipin 1 Represses NFATc4 Transcriptional Activity in Adipocytes To Inhibit Secretion of Inflammatory Factors

(2010) H. B. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

A Phosphatidic Acid Binding/Nuclear Localization Motif Determines Lipin1 Function in Lipid Metabolism and Adipogenesis

(2010) Hongmei Ren et al.   MOLECULAR BIOLOGY OF THE CELL

Phospholipase D2-Dependent Inhibition of the Nuclear Hormone Receptor PPARγ by Cyclic Phosphatidic Acid

(2010) Tamotsu Tsukahara et al.   MOLECULAR CELL

Sphingolipids and expression regulation of genes in cancer

(2010) Gauri A. Patwardhan et al.   PROGRESS IN LIPID RESEARCH

Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis

(2009) Kazuharu Takeuchi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

C/EBP transcription factors regulateSREBP1cgene expression during adipogenesis

(2009) Victoria A. Payne et al.   BIOCHEMICAL JOURNAL

Phosphatidate degradation: Phosphatidate phosphatases (lipins) and lipid phosphate phosphatases

(2009) David N. Brindley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy

(2009) Víctor A. Cortés et al.   Cell Metabolism

Inherited lipodystrophies and hypertriglyceridemia

(2009) Vinaya Simha et al.   CURRENT OPINION IN LIPIDOLOGY

Mechanisms of obesity and related pathologies: Transcriptional control of adipose tissue development

(2009) Cecile Vernochet et al.   FEBS Journal

A Conserved Serine Residue Is Required for the Phosphatidate Phosphatase Activity but Not the Transcriptional Coactivator Functions of Lipin-1 and Lipin-2

(2009) Jimmy Donkor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of the C. elegans lipin homolog leads to ER disorganization and to defects in the breakdown and reassembly of the nuclear envelope

(2009) A. Golden et al.   JOURNAL OF CELL SCIENCE

Enzymatic measurement of phosphatidic acid in cultured cells

(2009) Shin-ya Morita et al.   JOURNAL OF LIPID RESEARCH

Transcriptional factors that promote formation of white adipose tissue

(2009) Ursula A. White et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

Phosphatidic acid mediates demyelination in Lpin1 mutant mice

(2008) K. Nadra et al.   GENES & DEVELOPMENT

Role of Phosphatidic Acid in the Coupling of the ERK Cascade

(2008) Catherine A. Kraft et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipin1 Is a Key Factor for the Maturation and Maintenance of Adipocytes in the Regulatory Network with CCAAT/Enhancer-binding Protein α and Peroxisome Proliferator-activated Receptor γ2

(2008) Yoo-Kyung Koh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis

(2008) Peixiang Zhang et al.   JOURNAL OF LIPID RESEARCH

Metabolic syndrome: from epidemiology to systems biology

(2008) Aldons J. Lusis et al.   NATURE REVIEWS GENETICS

Structural basis for the activation of PPARγ by oxidized fatty acids

(2008) Toshimasa Itoh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ceramide 1-phosphate stimulates macrophage proliferation through activation of the PI3-kinase/PKB, JNK and ERK1/2 pathways

(2007) Patricia Gangoiti et al.   CELLULAR SIGNALLING