Targeting glycogen metabolism in bladder cancer

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Genomic, pathological, and clinical heterogeneity as drivers of personalized medicine in prostate cancer

(2015) Michael Fraser et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

KIAA1199 interacts with glycogen phosphorylase kinase β-subunit (PHKB) to promote glycogen breakdown and cancer cell survival

(2015) Masato Terashima et al.   Oncotarget

Glycogen storage disease type III: A novel Agl knockout mouse model

(2014) Serena Pagliarani et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cytotoxic and DNA-targeted therapy in urothelial cancer: Have we squeezed the lemon enough?

(2014) Arjun V. Balar et al.   CANCER

Chemotherapeutic and targeted biological agents for metastatic bladder cancer: A comprehensive review

(2014) Terence T Sio et al.   INTERNATIONAL JOURNAL OF UROLOGY

Role in Tumor Growth of a Glycogen Debranching Enzyme Lost in Glycogen Storage Disease

(2014) Sunny Guin et al.   JNCI-Journal of the National Cancer Institute

Mouse model of glycogen storage disease type III

(2014) Kai-Ming Liu et al.   MOLECULAR GENETICS AND METABOLISM

Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma1Present address: Department of Urology, University Hospital Frankfurt, Germany.2Equal contributions.

(2014) Meike Schneider et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Genomic Analysis as the First Step toward Personalized Treatment in Renal Cell Carcinoma

(2014) Zofia Felicja Bielecka et al.   Frontiers in Oncology

Increased sensitivity to glucose starvation correlates with downregulation of glycogen phosphorylase isoform PYGB in tumor cell lines resistant to 2-deoxy-d-glucose

(2013) Katherine B. Philips et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Molecular Pathways: Fumarate Hydratase-Deficient Kidney Cancer--Targeting the Warburg Effect in Cancer

(2013) W. M. Linehan et al.   CLINICAL CANCER RESEARCH

Neuromuscular Disorders of Glycogen Metabolism

(2013) Elisabetta Gazzerro et al.   Current Neurology and Neuroscience Reports

Glycogen phosphorylase inhibitors: a patent review (2008 – 2012)

(2013) Nicolas Gaboriaud-Kolar et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Rare insights into cancer biology

(2013) J Adam et al.   ONCOGENE

Personalized medicine for targeted and platinum-based chemotherapy of lung and bladder cancer

(2013) George D Cimino et al.   Bioanalysis

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

Non-glucose metabolism in cancer cells—is it all in the fat?

(2012) Swethajit Biswas et al.   CANCER AND METASTASIS REVIEWS

Glucose Utilization via Glycogen Phosphorylase Sustains Proliferation and Prevents Premature Senescence in Cancer Cells

(2012) Elena Favaro et al.   Cell Metabolism

ICUD-EAU International Consultation on Bladder Cancer 2012: Chemotherapy for Urothelial Carcinoma—Neoadjuvant and Adjuvant Settings

(2012) Cora N. Sternberg et al.   EUROPEAN UROLOGY

Emerging personalized approaches for the management of advanced urothelial carcinoma

(2012) Che-Kai Tsao et al.   Expert Review of Anticancer Therapy

Targeting of Several Glycolytic Enzymes Using RNA Interference Reveals Aldolase Affects Cancer Cell Proliferation through a Non-glycolytic Mechanism

(2012) Carolyn Ritterson Lew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular characterization of hepatocellular adenomas developed in patients with glycogen storage disease type I

(2012) Julien Calderaro et al.   JOURNAL OF HEPATOLOGY

Phase 2 Study of Adjuvant Intravesical Instillations of Apaziquone for High Risk Nonmuscle Invasive Bladder Cancer

(2012) K. Hendricksen et al.   JOURNAL OF UROLOGY

A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo

(2012) Y. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

(2012) M. Jain et al.   SCIENCE

Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival

(2012) Joffrey Pelletier et al.   Frontiers in Oncology

IKK  and NF- B Transcription Govern Lymphoma Cell Survival through AKT-Induced Plasma Membrane Trafficking of GLUT1

(2011) T. G. Sommermann et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Therapeutic targeting of cancer cell metabolism

(2011) Chi V. Dang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Inhibition of Glycogen Phosphorylation Induces Changes in Cellular Proteome and Signaling Pathways in MIA Pancreatic Cancer Cells

(2011) Danjun Ma et al.   PANCREAS

HIF-1 as a Target for Cancer Chemotherapy, Chemosensitization and Chemoprevention

(2011) Elena Monti et al.   Current Molecular Pharmacology

Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells

(2010) Lisa S. Pike et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Stable RNA interference of hexokinase II gene inhibits human colon cancer LoVo cell growth in vitro and in vivo

(2010) Qiuping Peng et al.   CANCER BIOLOGY & THERAPY

A phase I clinical trial of FOLFIRI in combination with the pan-cyclin-dependent kinase (CDK) inhibitor flavopiridol

(2010) Mark A. Dickson et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Glycogen Storage Disease Type III diagnosis and management guidelines

(2010) Priya S Kishnani et al.   GENETICS IN MEDICINE

The genetic basis of kidney cancer: a metabolic disease

(2010) W. Marston Linehan et al.   Nature Reviews Urology

Hypoxia Promotes Glycogen Accumulation through Hypoxia Inducible Factor (HIF)-Mediated Induction of Glycogen Synthase 1

(2010) Nuria Pescador et al.   PLoS One

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

(2010) A. Le et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMP-activated protein kinase - a sensor of glycogen as well as AMP and ATP?

(2009) A. McBride et al.   Acta Physiologica

De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy

(2009) T Mashima et al.   BRITISH JOURNAL OF CANCER

Phosphoglucose Isomerase/Autocrine Motility Factor Mediates Epithelial and Mesenchymal Phenotype Conversions in Breast Cancer

(2009) Tatsuyoshi Funasaka et al.   CANCER RESEARCH

Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

(2009) Daniel K. Nomura et al.   CELL

Abnormalities in Glucose Uptake and Metabolism in Imatinib-Resistant Human BCR-ABL-Positive Cells

(2009) D. J. Kominsky et al.   CLINICAL CANCER RESEARCH

Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease

(2009) Priya S. Kishnani et al.   HUMAN MOLECULAR GENETICS

SHMT1 and SHMT2 Are Functionally Redundant in Nuclear De novo Thymidylate Biosynthesis

(2009) Donald D. Anderson et al.   PLoS One

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Roles of p53, Myc and HIF-1 in Regulating Glycolysis — the Seventh Hallmark of Cancer

(2008) S. J. Yeung et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hyperlipidemia in glycogen storage disease type III: Effect of age and metabolic control

(2008) A. V. Bernier et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth

(2008) B. Clem et al.   MOLECULAR CANCER THERAPEUTICS

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

(2007) Jungwoon Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY