The gut microbiome, diet and links to cardiometabolic and chronic disorders

Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine

(2015) Suman Srinivasa et al.   AIDS

Frequency of Attainment of Low-Density Lipoprotein Cholesterol and Non–High-Density Lipoprotein Cholesterol Goals in Cardiovascular Clinical Practice (from the National Cardiovascular Data Registry PINNACLE Registry)

(2015) Sarah A. Spinler et al.   AMERICAN JOURNAL OF CARDIOLOGY

Canadian Society of Nephrology Commentary on the KDIGO Clinical Practice Guideline for CKD Evaluation and Management

(2015) Ayub Akbari et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

(2015) Saeed Shoaie et al.   Cell Metabolism

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

(2015) Valentina Tremaroli et al.   Cell Metabolism

TMAO Is Both a Biomarker and a Renal Toxin

(2015) A. M. Fogelman   CIRCULATION RESEARCH

Microbiota Metabolite Regulation of Host Immune Homeostasis: A Mechanistic Missing Link

(2015) S. Steinmeyer et al.   CURRENT ALLERGY AND ASTHMA REPORTS

How informative is the mouse for human gut microbiota research?

(2015) T. L. A. Nguyen et al.   Disease Models & Mechanisms

Healthy lifestyle interventions to combat noncommunicable disease—a novel nonhierarchical connectivity model for key stakeholders: a policy statement from the American Heart Association, European Society of Cardiology, European Association for Cardiovascular Prevention and Rehabilitation, and American College of Preventive Medicine

(2015) Ross Arena et al.   EUROPEAN HEART JOURNAL

High-density lipoprotein-based drug discovery for treatment of atherosclerosis

(2015) Yu Du et al.   Expert Opinion on Drug Discovery

Is there interaction between gut microbial profile and cardiovascular risk in chronic kidney disease patients?

(2015) Amanda F Barros et al.   Future Microbiology

Fecal microbiota analysis: an overview of sample collection methods and sequencing strategies

(2015) Vincent Thomas et al.   Future Microbiology

Intestinal Microbiota-Dependent Phosphatidylcholine Metabolites, Diastolic Dysfunction, and Adverse Clinical Outcomes in Chronic Systolic Heart Failure

(2015) W.H. Wilson Tang et al.   JOURNAL OF CARDIAC FAILURE

Associations of Trimethylamine N-Oxide With Nutritional and Inflammatory Biomarkers and Cardiovascular Outcomes in Patients New to Dialysis

(2015) George A. Kaysen et al.   JOURNAL OF RENAL NUTRITION

Microbiota—implications for immunity and transplantation

(2015) Jonathan S. Bromberg et al.   Nature Reviews Nephrology

Influence of Proton-Pump Inhibitors on the Luminal Microbiota in the Gastrointestinal Tract

(2015) Ayumi Tsuda et al.   Clinical and Translational Gastroenterology

From next-generation sequencing to systematic modeling of the gut microbiome

(2015) Boyang Ji et al.   Frontiers in Genetics

Expansion of Urease- and Uricase-Containing, Indole- and p-Cresol-Forming and Contraction of Short-Chain Fatty Acid-Producing Intestinal Microbiota in ESRD

(2014) Jakk Wong et al.   AMERICAN JOURNAL OF NEPHROLOGY

Effective dosing of L-carnitine in the secondary prevention of cardiovascular disease: a systematic review and meta-analysis

(2014) Ruiping Shang et al.   BMC Cardiovascular Disorders

Intestinal permeability – a new target for disease prevention and therapy

(2014) Stephan C Bischoff et al.   BMC GASTROENTEROLOGY

Processing faecal samples: a step forward for standards in microbial community analysis

(2014) Alba Santiago et al.   BMC MICROBIOLOGY

Dietary effects on human gut microbiome diversity

(2014) Zhenjiang Xu et al.   BRITISH JOURNAL OF NUTRITION

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Rethinking “Enterotypes”

(2014) Dan Knights et al.   Cell Host & Microbe

Microbial Modulation of Insulin Sensitivity

(2014) Muhammad Tanweer Khan et al.   Cell Metabolism

Cystatin C for Glomerular Filtration Rate Estimation: Coming of Age

(2014) A. S. Levey et al.   CLINICAL CHEMISTRY

The Effects of Gastrointestinal Surgery on Gut Microbiota: Potential Contribution to Improved Insulin Sensitivity

(2014) Judith Aron-Wisnewsky et al.   Current Atherosclerosis Reports

Gut Microbial Translocation in the Pathogenesis of Systemic Inflammation in Patients with End-Stage Renal Disease

(2014) Nosratola D. Vaziri   DIGESTIVE DISEASES AND SCIENCES

Gut Bacterial Translocation May Aggravate Microinflammation in Hemodialysis Patients

(2014) Kehui Shi et al.   DIGESTIVE DISEASES AND SCIENCES

Antibiotic treatments and microbes in the gut

(2014) Sandra Macfarlane   ENVIRONMENTAL MICROBIOLOGY

Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide

(2014) Z. Wang et al.   EUROPEAN HEART JOURNAL

Intestinal Epithelial Cell Toll-like Receptor 5 Regulates the Intestinal Microbiota to Prevent Low-Grade Inflammation and Metabolic Syndrome in Mice

(2014) Benoit Chassaing et al.   GASTROENTEROLOGY

Microbiota and diabetes: an evolving relationship

(2014) Herbert Tilg et al.   GUT

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents

(2014) A Psichas et al.   INTERNATIONAL JOURNAL OF OBESITY

Association of Bariatric Surgery With Long-term Remission of Type 2 Diabetes and With Microvascular and Macrovascular Complications

(2014) Lars Sjöström et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Oral, Capsulized, Frozen Fecal Microbiota Transplantation for RelapsingClostridium difficileInfection

(2014) Ilan Youngster et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prevalence of Obesity in the United States

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Transmission of Atherosclerosis Susceptibility with Gut Microbial Transplantation

(2014) Jill C. Gregory et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The contributory role of gut microbiota in cardiovascular disease

(2014) W.H. Wilson Tang et al.   JOURNAL OF CLINICAL INVESTIGATION

Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure

(2014) M. Trøseid et al.   JOURNAL OF INTERNAL MEDICINE

Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure

(2014) W.H. Wilson Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

The Effect of PPI Use on Human Gut Microbiota and Weight Loss in Patients Undergoing Laparoscopic Roux-en-Y Gastric Bypass

(2014) Emily K. Ward et al.   OBESITY SURGERY

The Impact of Different DNA Extraction Kits and Laboratories upon the Assessment of Human Gut Microbiota Composition by 16S rRNA Gene Sequencing

(2014) Nicholas A. Kennedy et al.   PLoS One

Dietary Patterns Differently Associate with Inflammation and Gut Microbiota in Overweight and Obese Subjects

(2014) Ling Chun Kong et al.   PLoS One

In Vitro Characterization of the Impact of Different Substrates on Metabolite Production, Energy Extraction and Composition of Gut Microbiota from Lean and Obese Subjects

(2014) Marisol Aguirre et al.   PLoS One

Dietary history contributes to enterotype-like clustering and functional metagenomic content in the intestinal microbiome of wild mice

(2014) Jun Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status

(2014) Amandine Everard et al.   Nature Communications

Diet and the development of the human intestinal microbiome

(2014) Noah Voreades et al.   Frontiers in Microbiology

Guidelines for Diagnosis, Treatment and Prevention of Clostridium difficile Infections

(2013) Christina M Surawicz et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Evaluation and Management of Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2012 Clinical Practice Guideline

(2013) Paul E. Stevens   ANNALS OF INTERNAL MEDICINE

Gut microbiota: An environmental risk factor for cardiovascular disease

(2013) Jane Stock   ATHEROSCLEROSIS

Gut microbiota metabolism of l-carnitine and cardiovascular risk

(2013) John R. Ussher et al.   ATHEROSCLEROSIS

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

(2013) Brian J. Bennett et al.   Cell Metabolism

Renal Function Following Three Distinct Weight Loss Dietary Strategies During 2 Years of a Randomized Controlled Trial

(2013) A. Tirosh et al.   DIABETES CARE

An increase in theAkkermansiaspp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice

(2013) Na-Ri Shin et al.   GUT

L-Carnitine in the Secondary Prevention of Cardiovascular Disease: Systematic Review and Meta-analysis

(2013) James J. DiNicolantonio et al.   MAYO CLINIC PROCEEDINGS

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Dietary intervention impact on gut microbial gene richness

(2013) Aurélie Cotillard et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Gut metagenome in European women with normal, impaired and diabetic glucose control

(2013) Fredrik H. Karlsson et al.   NATURE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

What has high-throughput sequencing ever done for us?

(2013) Julian Parkhill   NATURE REVIEWS MICROBIOLOGY

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

Changes in Intestinal Permeability after Roux-en-Y Gastric Bypass

(2013) Alexandre Lages Savassi-Rocha et al.   OBESITY SURGERY

Roux-en-Y gastric bypass surgery in rats alters gut microbiota profile along the intestine

(2013) Melania Osto et al.   PHYSIOLOGY & BEHAVIOR

Human Gut Microbiota Changes Reveal the Progression of Glucose Intolerance

(2013) Xiuying Zhang et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dietary Modification of the Microbiome Affects Risk for Cardiovascular Disease

(2013) Andrew R. Mendelsohn et al.   REJUVENATION RESEARCH

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity

(2013) A. P. Liou et al.   Science Translational Medicine

Transcriptomic fingerprinting ofPseudomonas putidaunder alternative physiological regimes

(2013) Juhyun Kim et al.   Environmental Microbiology Reports

A Guide to Enterotypes across the Human Body: Meta-Analysis of Microbial Community Structures in Human Microbiome Datasets

(2013) Omry Koren et al.   PLoS Computational Biology

Storage conditions of intestinal microbiota matter in metagenomic analysis

(2012) Silvia Cardona et al.   BMC MICROBIOLOGY

Systematic reviews of the role of omega-3 fatty acids in the prevention and treatment of disease

(2012) Angel Gil et al.   BRITISH JOURNAL OF NUTRITION

The Impact of the Gut Microbiota on Human Health: An Integrative View

(2012) Jose C. Clemente et al.   CELL

Muscle-Specific Deletion of Carnitine Acetyltransferase Compromises Glucose Tolerance and Metabolic Flexibility

(2012) Deborah M. Muoio et al.   Cell Metabolism

Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice

(2012) B. M. Carvalho et al.   DIABETOLOGIA

Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome

(2012) Anne Vrieze et al.   GASTROENTEROLOGY

Bariatric Surgery and Long-term Cardiovascular Events

(2012) Lars Sjöström et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Chronic kidney disease alters intestinal microbial flora

(2012) Nosratola D. Vaziri et al.   KIDNEY INTERNATIONAL

Gut microbiota composition correlates with diet and health in the elderly

(2012) Marcus J. Claesson et al.   NATURE

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

The importance of the gut microbiota after bariatric surgery

(2012) Judith Aron-Wisnewsky et al.   Nature Reviews Gastroenterology & Hepatology

Categorization of the gut microbiota: enterotypes or gradients?

(2012) Ian B. Jeffery et al.   NATURE REVIEWS MICROBIOLOGY

Gut bacterial translocation is associated with microinflammation in end-stage renal disease patients

(2012) FEIQIAN WANG et al.   NEPHROLOGY

A Core Human Microbiome as Viewed through 16S rRNA Sequence Clusters

(2012) Susan M. Huse et al.   PLoS One

Symptomatic atherosclerosis is associated with an altered gut metagenome

(2012) Fredrik H. Karlsson et al.   Nature Communications

The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases

(2011) Helena Tlaskalová-Hogenová et al.   Cellular & Molecular Immunology

CD14 Modulates Inflammation-Driven Insulin Resistance

(2011) J. M. Fernandez-Real et al.   DIABETES

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

(2011) Amandine Everard et al.   DIABETES

Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept

(2011) J. Amar et al.   DIABETOLOGIA

Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment

(2011) Jacques Amar et al.   EMBO Molecular Medicine

Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency

(2011) Robert Ringseis et al.   EUROPEAN JOURNAL OF NUTRITION

The human gut virome: Inter-individual variation and dynamic response to diet

(2011) S. Minot et al.   GENOME RESEARCH

Effect of Bariatric Surgery-Induced Weight Loss on SR-BI-, ABCG1-, and ABCA1-Mediated Cellular Cholesterol Efflux in Obese Women

(2011) Judith Aron-Wisnewsky et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Gut microbiome, obesity, and metabolic dysfunction

(2011) Herbert Tilg et al.   JOURNAL OF CLINICAL INVESTIGATION

Omega-3 Fatty Acids and Cardiovascular Disease

(2011) Dariush Mozaffarian et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Intestinal Permeability Is Associated With Visceral Adiposity in Healthy Women

(2011) Anders Gummesson et al.   Obesity

Responses of Gut Microbiota to Diet Composition and Weight Loss in Lean and Obese Mice

(2011) Yann Ravussin et al.   Obesity

Depletion of Murine Intestinal Microbiota: Effects on Gut Mucosa and Epithelial Gene Expression

(2011) Dag Henrik Reikvam et al.   PLoS One

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Differential Adaptation of Human Gut Microbiota to Bariatric Surgery-Induced Weight Loss: Links With Metabolic and Low-Grade Inflammation Markers

(2010) J.-P. Furet et al.   DIABETES

Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models

(2010) E F Murphy et al.   GUT

Dominant and diet-responsive groups of bacteria within the human colonic microbiota

(2010) Alan W Walker et al.   ISME Journal

Human oral, gut, and plaque microbiota in patients with atherosclerosis

(2010) O. Koren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased prevalence of subclinical coronary atherosclerosis detected by coronary computed tomography angiography in HIV-infected men

(2009) Janet Lo et al.   AIDS

How Do We Define Cure of Diabetes?

(2009) J. B. Buse et al.   DIABETES CARE

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Reproducible Community Dynamics of the Gastrointestinal Microbiota following Antibiotic Perturbation

(2009) D. A. Antonopoulos et al.   INFECTION AND IMMUNITY

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

(2009) Kendle M. Maslowski et al.   NATURE

Human gut microbiota in obesity and after gastric bypass

(2009) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Human colonic microbiota associated with diet, obesity and weight loss

(2008) S H Duncan et al.   INTERNATIONAL JOURNAL OF OBESITY

Next-generation DNA sequencing

(2008) Jay Shendure et al.   NATURE BIOTECHNOLOGY

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA