Article
Cardiac & Cardiovascular Systems
Aleksandra Kolarczyk-Haczyk, Marta Konopko, Marta Mazur, Aleksander Zurakowski, Mariusz Gasior, Maciej Rogala, Piotr Jankowski, Pawel Kazmierczak, Krzysztof P. Milewski, Pawel E. Buszman, Piotr P. Buszman
Summary: The KOS-MI Program, which includes complete revascularization, rehabilitation, and cardiac care, has been shown to improve long-term prognosis for patients after myocardial infarction (MI) at 3-year follow-up.
KARDIOLOGIA POLSKA
(2023)
Article
Emergency Medicine
Jesse T. T. Mclaren, Mazen El -Baba, Varunaavee Sivashanmugathas, H. Pendell Meyers, Stephen W. Smith, Lucas B. Chartier
Summary: There are differences in the hospital course of patients with acute coronary syndrome using STEMI and OMI paradigms in the emergency department. STEMI criteria miss a majority of OMI, while the OMI paradigm reveals opportunities for improvement.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Article
Medicine, General & Internal
Jie Zhao, Stephen Burgess, Bohan Fan, C. Mary Schooling
Summary: This study does not support a beneficial association between L-carnitine and CVD and its risk factors, but suggests potential harm. L-carnitine may also play a sex-specific role in CAD.
Review
Hematology
Graham H. Bevan, Sadeer G. Al-Kindi, Robert D. Brook, Thomas Muenzel, Sanjay Rajagopalan
Summary: Ambient air pollution from particulate matter <= 2.5μm is a major environmental risk factor contributing to global mortality, particularly due to atherosclerotic cardiovascular diseases. Studies suggest that even at levels below air quality guidelines in North America and Europe, there is a continued association between particulate matter <= 2.5 levels and ASCVD. Research in animals and humans has provided insights into the mechanisms through which air pollution exposure may predispose individuals to atherosclerosis.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Davide Capodanno, William Wijns
Summary: In a study on patients with coronary artery disease, it was found that reducing the occurrence of non-fatal myocardial infarctions does not necessarily lead to a reduction in overall or cardiovascular mortality.
NATURE REVIEWS CARDIOLOGY
(2022)
Article
Medicine, General & Internal
W. Schuyler Jones, Hillary Mulder, Lisa M. Wruck, Michael J. Pencina, Sunil Kripalani, Daniel Munoz, David L. Crenshaw, Mark B. Effron, Richard N. Re, Kamal Gupta, R. David Anderson, Carl J. Pepine, Eileen M. Handberg, Brittney R. Manning, Sandeep K. Jain, Saket Girotra, Danielle Riley, Darren A. DeWalt, Jeff Whittle, Ythan H. Goldberg, Veronique L. Roger, Rachel Hess, Catherine P. Benziger, Peter Farrehi, Li Zhou, Daniel E. Ford, Kevin Haynes, Jeffrey J. VanWormer, Kirk U. Knowlton, Jennifer L. Kraschnewski, Tamar S. Polonsky, Dan J. Fintel, Faraz S. Ahmad, James C. McClay, James R. Campbell, Douglas S. Bell, Gregg C. Fonarow, Steven M. Bradley, Anuradha Paranjape, Matthew T. Roe, Holly R. Robertson, Lesley H. Curtis, Amber G. Sharlow, Lisa G. Berdan, Bradley G. Hammill, Debra F. Harris, Laura G. Qualls, Guillaume Marquis-Gravel, Madelaine F. Modrow, Gregory M. Marcus, Thomas W. Carton, Elizabeth Nauman, Lemuel R. Waitman, Abel N. Kho, Elizabeth A. Shenkman, Kathleen M. McTigue, Rainu Kaushal, Frederick A. Masoudi, Elliott M. Antman, Desiree R. Davidson, Kevin Edgley, James G. Merritt, Linda S. Brown, Doris N. Zemon, Thomas E. McCormick, Jacqueline D. Alikhaani, Kenneth C. Gregoire, Russell L. Rothman, Robert A. Harrington, Adrian F. Hernandez
Summary: In an open-label, pragmatic trial, patients with cardiovascular disease were randomly assigned to a strategy of 81 mg or 325 mg of aspirin daily. A substantial proportion of those assigned to the 325-mg dose switched to the 81-mg dose, and there were no significant differences in cardiovascular events or major bleeding between the two groups.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Yifang Zhou, Yidan Liu, Ruixiang Zeng, Wenjie Qiu, Yunhong Zhao, Yuanshen Zhou
Summary: This study found that early low-dose long-term colchicine can reduce the risk of major adverse cardiovascular events (MACE) in patients with acute myocardial infarction (AMI) through anti-inflammation, without leading to more gastrointestinal adverse events.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Gemma A. Figtree, Bjorn Redfors, Rebecca Kozor, Stephen T. Vernon, Stuart M. Grieve, Jawad Mazhar, Holger Thiele, Manesh R. Patel, James E. Udelson, Harry P. Selker, E. Magnus Ohman, Akiko Maehara, Dmitri Karmpaliotis, Ingo Eitel, Christopher B. Granger, Ori Ben-Yehuda, Gregg W. Stone, Ioanna Kosmidou
Summary: First-presentation STEMI patients without standard modifiable cardiovascular risk factors (SMuRFs) have a higher risk of Thrombolysis In Myocardial Infarction flow grade 0/1 pre-PCI. However, after adjustment, there were no significant associations between SMuRF-less status and infarct size, left ventricular ejection fraction, or mortality.
JACC-CARDIOVASCULAR INTERVENTIONS
(2022)
Article
Cardiac & Cardiovascular Systems
Amil. M. M. Shah, Brian Claggett, Narayana Prasad, Guichu Li, Mayra Volquez, Karola Jering, Maja Cikes, Attila Kovacs, Wilfried Mullens, Jose C. Nicolau, Lars Kober, Peter Van der Meer, Pardeep. S. S. Jhund, Ghionul Ibram, Martin Lefkowitz, Yinong Zhou, Scott. D. D. Solomon, Marc A. Pfeffer
Summary: This study compared the effects of sacubitril/valsartan and ramipril on left ventricular function and adverse remodeling after acute myocardial infarction (AMI). The results showed that patients randomized to sacubitril/valsartan had better improvements in filling pressure, left ventricular volume changes, and other aspects compared to those randomized to ramipril.
Article
Biochemistry & Molecular Biology
Niu Liu, Yingni Zhu, Wei Song, Wujing Ren, Zhenjun Tian
Summary: This study characterized the temporal expression of ALCAT1 in post-myocardial infarction (MI) and demonstrated that aerobic exercise can reverse the upregulation of ALCAT1, reduce oxidative stress and apoptosis in MI rats.
Review
Environmental Sciences
Wentao Zhu, Jiajie Cai, Yuchen Hu, Haodan Zhang, Xiao Han, Huiqiu Zheng, Jing Wu
Summary: A meta-analysis showed a significant association between long-term exposure to PM2.5 and increased risks of myocardial infarction (MI) and post-MI mortality. There was no apparent publication bias, indicating the reliability of the results. These findings may have implications for improving public health and policy-making.
Article
Medicine, General & Internal
Gregory Y. H. Lip, Ash Genaidy, George Tran, Patricia Marroquin, Cara Estes, Sue Sloop
Summary: This study demonstrates the association between COVID-19 and myocardial infarction (MI), and the importance of cardiometabolic and noncardiometabolic multimorbidity in increasing the risk of COVID-19 infection and MI complications.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2022)
Article
Cell Biology
Elvira Forte, Mona Panahi, Nicoleta Baxan, Fu Siong Ng, Joseph J. Boyle, Jane Branca, Olivia Bedard, Muneer G. Hasham, Lindsay Benson, Sian E. Harding, Nadia Rosenthal, Susanne Sattler
Summary: High dose isoproterenol can cause myocardial necrosis and trigger an adaptive immune response targeting the heart, leading to the development of autoimmune heart disease.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Hangzhuo Li, Shuguang Qin, Qiaoqin Liang, Yue Xi, Wenyan Bo, Mengxin Cai, Zhenjun Tian
Summary: Different types of exercise and skeletal muscle electrical stimulation can up-regulate the expression of irisin/FNDC5 in the myocardium, promoting mitophagy and improving cardiac function. Resistance exercise can improve cardiac function by activating the irisin/FNDC5-PINK1/Parkin-LC3/P62 pathway and inhibiting oxidative stress.
Review
Environmental Sciences
Yifang Liu, Shijiao Yan, Li Zou, Jing Wen, Wenning Fu
Summary: This study conducted a dose-response meta-analysis and found a positive dose-response relationship between various types of noise exposure and the incidence and mortality of myocardial infarction (MI). The linear models showed that for each 10 dB(A) increase in noise exposure, the risk of MI incidence increased by 1.04 times and the risk of MI mortality increased by 1.02 times. Additionally, a J-shaped dose-response relationship between noise and MI mortality was observed, with a possible threshold of 42 dB(A) for the statistical impact of noise on MI mortality.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)