标题
Anaemia in kidney disease: harnessing hypoxia responses for therapy
作者
关键词
-
出版物
Nature Reviews Nephrology
Volume 11, Issue 7, Pages 394-410
出版商
Springer Nature
发表日期
2015-06-09
DOI
10.1038/nrneph.2015.82
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Diverse origins of the myofibroblast—implications for kidney fibrosis
- (2015) Lucas L. Falke et al. Nature Reviews Nephrology
- Abnormal erythropoiesis and the pathophysiology of chronic anemia
- (2014) Mark J. Koury BLOOD REVIEWS
- A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression
- (2014) F. Storti et al. HAEMATOLOGICA
- Cell-specific translational profiling in acute kidney injury
- (2014) Jing Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- The role of spatial organization of cells in erythropoiesis
- (2014) N. Eymard et al. JOURNAL OF MATHEMATICAL BIOLOGY
- Chronic Hypoxia-Inducible Transcription Factor-2 Activation Stably Transforms Juxtaglomerular Renin Cells into Fibroblast-Like Cells In Vivo
- (2014) B. Kurt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Identification of erythroferrone as an erythroid regulator of iron metabolism
- (2014) Léon Kautz et al. NATURE GENETICS
- Mimicking Hypoxia to Treat Anemia: HIF-Stabilizer BAY 85-3934 (Molidustat) Stimulates Erythropoietin Production without Hypertensive Effects
- (2014) Ingo Flamme et al. PLoS One
- Short-term treatment with a novel HIF-prolyl hydroxylase inhibitor (GSK1278863) failed to improve measures of performance in subjects with claudication-limited peripheral artery disease
- (2014) Eric Olson et al. VASCULAR MEDICINE
- Identification of a Multipotent Self-Renewing Stromal Progenitor Population during Mammalian Kidney Organogenesis
- (2014) Akio Kobayashi et al. Stem Cell Reports
- Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
- (2013) Gregg L. Semenza Annual Review of Pathology-Mechanisms of Disease
- [(4-Hydroxyl-benzo[4,5]thieno[3,2-c]pyridine-3-carbonyl)-amino]-acetic acid derivatives; HIF prolyl 4-hydroxylase inhibitors as oral erythropoietin secretagogues
- (2013) Yong Rae Hong et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2 mRNA translation
- (2013) N. Wilkinson et al. BLOOD
- Regulation of erythropoiesis by hypoxia-inducible factors
- (2013) Volker H. Haase BLOOD REVIEWS
- The IRP1-HIF-2α Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption
- (2013) Sheila A. Anderson et al. Cell Metabolism
- Deletion of Iron Regulatory Protein 1 Causes Polycythemia and Pulmonary Hypertension in Mice through Translational Derepression of HIF2α
- (2013) Manik C. Ghosh et al. Cell Metabolism
- Intolerability of cobalt salt as erythropoietic agent
- (2013) Bastian Ebert et al. Drug Testing and Analysis
- HIF and pulmonary vascular responses to hypoxia
- (2013) Larissa A. Shimoda et al. JOURNAL OF APPLIED PHYSIOLOGY
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Oxygen Sensors: Tricking the Body into Mounting Orchestrated Survival and Repair Responses
- (2013) Michael H. Rabinowitz JOURNAL OF MEDICINAL CHEMISTRY
- Deletion of von Hippel-Lindau Protein Converts Renin-Producing Cells into Erythropoietin-Producing Cells
- (2013) B. Kurt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Plasticity of Renal Erythropoietin-Producing Cells Governs Fibrosis
- (2013) T. Souma et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors
- (2013) Lingbo Zhang et al. NATURE
- HIF isoforms in the skin differentially regulate systemic arterial pressure
- (2013) A. S. Cowburn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A mouse model of adult-onset anaemia due to erythropoietin deficiency
- (2013) Shun Yamazaki et al. Nature Communications
- Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis
- (2012) A. Laitala et al. BLOOD
- Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling
- (2012) C. Besson-Fournier et al. BLOOD
- Treatment of erythropoietin deficiency in mice with systemically administered siRNA
- (2012) W. Querbes et al. BLOOD
- HIF-1 is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2 -induced excessive erythropoiesis
- (2012) K. Franke et al. BLOOD
- The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO
- (2012) Erinn B. Rankin et al. CELL
- Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis
- (2012) Qingdu Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- Mammalian Kidney Development: Principles, Progress, and Projections
- (2012) M. H. Little et al. Cold Spring Harbor Perspectives in Biology
- The HIF Pathway and Erythrocytosis
- (2011) Frank S. Lee et al. Annual Review of Pathology-Mechanisms of Disease
- Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts
- (2011) D.-L. Zhang et al. BLOOD
- High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
- (2011) J. Schodel et al. BLOOD
- Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways
- (2011) M. Koulnis et al. BLOOD
- The multifunctional role of EKLF/KLF1 during erythropoiesis
- (2011) M. Siatecka et al. BLOOD
- Deletion of HIF-2 in the enterocytes decreases the severity of tissue iron loading in hepcidin knockout mice
- (2011) M. Mastrogiannaki et al. BLOOD
- Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression
- (2011) V. R. Gordeuk et al. BLOOD
- Chronic IFN- production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis
- (2011) S. F. Libregts et al. BLOOD
- Normal and disordered reticulocyte maturation
- (2011) Paul A Ney CURRENT OPINION IN HEMATOLOGY
- Stress erythropoiesis: new signals and new stress progenitor cells
- (2011) Robert F Paulson et al. CURRENT OPINION IN HEMATOLOGY
- FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors
- (2011) Elena Mancini et al. EMBO JOURNAL
- Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice
- (2011) Matthew Taylor et al. GASTROENTEROLOGY
- Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis
- (2011) M. Mastrogiannaki et al. HAEMATOLOGICA
- Genetic determinants of Tibetan high-altitude adaptation
- (2011) Tatum S. Simonson et al. HUMAN GENETICS
- Herpesvirus entry mediator regulates hypoxia-inducible factor–1α and erythropoiesis in mice
- (2011) Yukimi Sakoda et al. JOURNAL OF CLINICAL INVESTIGATION
- Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice
- (2011) Nariaki Asada et al. JOURNAL OF CLINICAL INVESTIGATION
- Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner
- (2011) Chih-Kang Chiang et al. LABORATORY INVESTIGATION
- Specific Contribution of the Erythropoietin Gene 3' Enhancer to Hepatic Erythropoiesis after Late Embryonic Stages
- (2011) N. Suzuki et al. MOLECULAR AND CELLULAR BIOLOGY
- Pharmacological Characterization of 1-(5-Chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic Acid (JNJ-42041935), a Potent and Selective Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor
- (2011) T. D. Barrett et al. MOLECULAR PHARMACOLOGY
- Negative Autoregulation by Fas Stabilizes Adult Erythropoiesis and Accelerates Its Stress Response
- (2011) Miroslav Koulnis et al. PLoS One
- Acute Vhl Gene Inactivation Induces Cardiac HIF-Dependent Erythropoietin Gene Expression
- (2011) Marta Miró-Murillo et al. PLoS One
- Isolation and Characterization of Renal Erythropoietin-Producing Cells from Genetically Produced Anemia Mice
- (2011) Xiaoqing Pan et al. PLoS One
- Erythropoietin stimulates spleen BMP4-dependent stress erythropoiesis and partially corrects anemia in a mouse model of generalized inflammation
- (2010) S. Millot et al. BLOOD
- Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia
- (2010) P. P. Kapitsinou et al. BLOOD
- Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
- (2010) Samira Lakhal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deficiency of a Transmembrane Prolyl 4-Hydroxylase in the Zebrafish Leads to Basement Membrane Defects and Compromised Kidney Function
- (2010) Jaana Hyvärinen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The von Hippel–Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice
- (2010) Michele M. Hickey et al. JOURNAL OF CLINICAL INVESTIGATION
- Of Mice and Men: Therapeutic mTOR Inhibition in Polycystic Kidney Disease
- (2010) Y. Pei JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Inhibition of Prolyl Hydroxylases Increases Erythropoietin Production in ESRD
- (2010) W. M. Bernhardt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Iron supplementation to treat anemia in patients with chronic kidney disease
- (2010) Anatole Besarab et al. Nature Reviews Nephrology
- Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
- (2010) Y. A. Minamishima et al. SCIENCE
- Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases
- (2010) Christoph Loenarz et al. TRENDS IN BIOCHEMICAL SCIENCES
- What Is So Bad About a Hemoglobin Level of 12 to 13 g/dL for Chronic Kidney Disease Patients Anyway?
- (2009) Anatole Besarab et al. ADVANCES IN CHRONIC KIDNEY DISEASE
- Intravenous Iron Versus Erythropoiesis-Stimulating Agents: Friends or Foes in Treating Chronic Kidney Disease Anemia?
- (2009) Kamyar Kalantar-Zadeh et al. ADVANCES IN CHRONIC KIDNEY DISEASE
- HIF-Prolyl Hydroxylases in the Rat Kidney
- (2009) Johannes Schödel et al. AMERICAN JOURNAL OF PATHOLOGY
- Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis
- (2009) Benjamin D. Humphreys et al. AMERICAN JOURNAL OF PATHOLOGY
- Pathophysiological Consequences of HIF Activation
- (2009) Volker H. Haase Annals of the New York Academy of Sciences
- Erythropoietin and the skin: a role for epidermal oxygen sensing?
- (2009) Ralf Paus et al. BIOESSAYS
- Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency
- (2009) Yatrik M. Shah et al. Cell Metabolism
- A Ferroportin Transcript that Lacks an Iron-Responsive Element Enables Duodenal and Erythroid Precursor Cells to Evade Translational Repression
- (2009) De-Liang Zhang et al. Cell Metabolism
- Hemoglobin Variability in Nondialysis Chronic Kidney Disease: Examining the Association with Mortality
- (2009) N. C. Boudville et al. Clinical Journal of the American Society of Nephrology
- HIF-2α, but not HIF-1α, promotes iron absorption in mice
- (2009) Maria Mastrogiannaki et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization
- (2009) Alexander Paliege et al. KIDNEY INTERNATIONAL
- A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease
- (2009) Marc A. Pfeffer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney
- (2008) Shuei-Liong Lin et al. AMERICAN JOURNAL OF PATHOLOGY
- The microenvironment for erythropoiesis is regulated by HIF-2 through VCAM-1 in endothelial cells
- (2008) T. Yamashita et al. BLOOD
- Repression via the GATA box is essential for tissue-specific erythropoietin gene expression
- (2008) N. Obara et al. BLOOD
- Erythroblastic islands: niches for erythropoiesis
- (2008) J. A. Chasis et al. BLOOD
- Erythrocyte vesiculation: a self-protective mechanism?
- (2008) Frans L. A. Willekens et al. BRITISH JOURNAL OF HAEMATOLOGY
- Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response
- (2008) Adam T. Boutin et al. CELL
- The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin
- (2008) Laura Silvestri et al. Cell Metabolism
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
- Expanding chemical biology of 2-oxoglutarate oxygenases
- (2008) Christoph Loenarz et al. Nature Chemical Biology
- A Gain-of-Function Mutation in theHIF2AGene in Familial Erythrocytosis
- (2008) Melanie J. Percy et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
- (2008) X. Du et al. SCIENCE
- Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins
- (2007) K. Takeda et al. BLOOD
- Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
- (2007) Y. A. Minamishima et al. BLOOD
- Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis
- (2007) L. Silvestri et al. BLOOD
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