标题
Methods of integrating data to uncover genotype–phenotype interactions
作者
关键词
-
出版物
NATURE REVIEWS GENETICS
Volume 16, Issue 2, Pages 85-97
出版商
Springer Nature
发表日期
2015-01-13
DOI
10.1038/nrg3868
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Launching genomics into the cloud: deployment of Mercury, a next generation sequence analysis pipeline
- (2014) Jeffrey G Reid et al. BMC BIOINFORMATICS
- Bionimbus: a cloud for managing, analyzing and sharing large genomics datasets
- (2014) Allison P Heath et al. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
- Efficient multivariate linear mixed model algorithms for genome-wide association studies
- (2014) Xiang Zhou et al. NATURE METHODS
- Diverse convergent evidence in the genetic analysis of complex disease: coordinating omic, informatic, and experimental evidence to better identify and validate risk factors
- (2014) Timothy H Ciesielski et al. BioData Mining
- ATHENA: the analysis tool for heritable and environmental network associations
- (2013) Emily R. Holzinger et al. BIOINFORMATICS
- Bayesian consensus clustering
- (2013) Eric F. Lock et al. BIOINFORMATICS
- Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls
- (2013) Wei Zheng et al. HUMAN MOLECULAR GENETICS
- Transcriptome and genome sequencing uncovers functional variation in humans
- (2013) Tuuli Lappalainen et al. NATURE
- Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
- (2013) Yun Liu et al. NATURE BIOTECHNOLOGY
- Genome-wide association studies identify four ER negative–specific breast cancer risk loci
- (2013) Montserrat Garcia-Closas et al. NATURE GENETICS
- Large-scale genotyping identifies 41 new loci associated with breast cancer risk
- (2013) Kyriaki Michailidou et al. NATURE GENETICS
- Single-cell sequencing-based technologies will revolutionize whole-organism science
- (2013) Ehud Shapiro et al. NATURE REVIEWS GENETICS
- GobyWeb: Simplified Management and Analysis of Gene Expression and DNA Methylation Sequencing Data
- (2013) Kevin C. Dorff et al. PLoS One
- Extensive Variation in Chromatin States Across Humans
- (2013) M. Kasowski et al. SCIENCE
- Identification of Genetic Variants That Affect Histone Modifications in Human Cells
- (2013) G. McVicker et al. SCIENCE
- ATHENA: Identifying interactions between different levels of genomic data associated with cancer clinical outcomes using grammatical evolution neural network
- (2013) Dokyoon Kim et al. BioData Mining
- A Computational Workflow to Identify Allele-specific Expression and Epigenetic Modification in Maize
- (2013) Xiaoxing Wei et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- Bayesian correlated clustering to integrate multiple datasets
- (2012) Paul Kirk et al. BIOINFORMATICS
- Matrix eQTL: ultra fast eQTL analysis via large matrix operations
- (2012) A. A. Shabalin BIOINFORMATICS
- A Bayesian Integrative Genomic Model for Pathway Analysis of Complex Traits
- (2012) Brooke L. Fridley et al. GENETIC EPIDEMIOLOGY
- Annotation of functional variation in personal genomes using RegulomeDB
- (2012) A. P. Boyle et al. GENOME RESEARCH
- Synergistic effect of different levels of genomic data for cancer clinical outcome prediction
- (2012) Dokyoon Kim et al. JOURNAL OF BIOMEDICAL INFORMATICS
- Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS
- (2012) Zia Khan et al. Molecular Systems Biology
- The nature of confounding in genome-wide association studies
- (2012) Bjarni J. Vilhjálmsson et al. NATURE REVIEWS GENETICS
- Next-generation proteomics: towards an integrative view of proteome dynamics
- (2012) A. F. Maarten Altelaar et al. NATURE REVIEWS GENETICS
- Experimental validation of in silico predicted KCNA1, KCNA2, KCNA6 and KCNQ2 genes for association studies of peripheral nerve hyperexcitability syndrome in Jack Russell Terriers
- (2012) Mario Van Poucke et al. NEUROMUSCULAR DISORDERS
- Integrating heterogeneous high-throughput data for meta-dimensional pharmacogenomics and disease-related studies
- (2012) Emily R Holzinger et al. PHARMACOGENOMICS
- Integrative Subtype Discovery in Glioblastoma Using iCluster
- (2012) Ronglai Shen et al. PLoS One
- A Two-Stage Random Forest-Based Pathway Analysis Method
- (2012) Ren-Hua Chung et al. PLoS One
- Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation
- (2012) Jun Zhu et al. PLOS BIOLOGY
- Computational prediction and experimental validation associating FABP-1 and pancreatic adenocarcinoma with diabetes
- (2011) Ravi N Sharaf et al. BMC GASTROENTEROLOGY
- Next generation sequencing based approaches to epigenomics
- (2011) M. Hirst et al. Briefings in Functional Genomics
- Pitfalls of merging GWAS data: lessons learned in the eMERGE network and quality control procedures to maintain high data quality
- (2011) Rebecca L. Zuvich et al. GENETIC EPIDEMIOLOGY
- A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese
- (2011) Kazuma Kiyotani et al. HUMAN MOLECULAR GENETICS
- AlleleSeq: analysis of allele-specific expression and binding in a network framework
- (2011) J. Rozowsky et al. Molecular Systems Biology
- HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
- (2011) L. D. Ward et al. NUCLEIC ACIDS RESEARCH
- Time to Recurrence and Survival in Serous Ovarian Tumors Predicted from Integrated Genomic Profiles
- (2011) Parminder K. Mankoo et al. PLoS One
- An Integrated Approach to Uncover Drivers of Cancer
- (2010) Uri David Akavia et al. CELL
- Quality control and quality assurance in genotypic data for genome-wide association studies
- (2010) Cathy C. Laurie et al. GENETIC EPIDEMIOLOGY
- The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
- (2010) A. McKenna et al. GENOME RESEARCH
- RNA sequencing: advances, challenges and opportunities
- (2010) Fatih Ozsolak et al. NATURE REVIEWS GENETICS
- Next-generation genomics: an integrative approach
- (2010) R. David Hawkins et al. NATURE REVIEWS GENETICS
- Principles and challenges of genome-wide DNA methylation analysis
- (2010) Peter W. Laird NATURE REVIEWS GENETICS
- ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
- (2010) K. Wang et al. NUCLEIC ACIDS RESEARCH
- ATHENA: A knowledge-based hybrid backpropagation-grammatical evolution neural network algorithm for discovering epistasis among quantitative trait Loci
- (2010) Stephen D Turner et al. BioData Mining
- The case for cloud computing in genome informatics
- (2010) Lincoln D Stein GENOME BIOLOGY
- RNA-seq: from technology to biology
- (2009) Samuel Marguerat et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Sequencing technologies — the next generation
- (2009) Michael L. Metzker NATURE REVIEWS GENETICS
- ChIP–seq: advantages and challenges of a maturing technology
- (2009) Peter J. Park NATURE REVIEWS GENETICS
- Selective inference in complex research
- (2009) Y. Benjamini et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
- Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture
- (2009) Casey S. Greene et al. PLoS One
- Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions
- (2009) Soumya Raychaudhuri et al. PLoS Genetics
- Spatially Uniform ReliefF (SURF) for computationally-efficient filtering of gene-gene interactions
- (2009) Casey S Greene et al. BioData Mining
- Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity
- (2008) C. M. Hartford et al. BLOOD
- Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans
- (2008) R. S. Huang et al. MOLECULAR CANCER THERAPEUTICS
- Genetics of gene expression and its effect on disease
- (2008) Valur Emilsson et al. NATURE
- Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks
- (2008) Jun Zhu et al. NATURE GENETICS
- RNA-Seq: a revolutionary tool for transcriptomics
- (2008) Zhong Wang et al. NATURE REVIEWS GENETICS
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