Diverse convergent evidence in the genetic analysis of complex disease: coordinating omic, informatic, and experimental evidence to better identify and validate risk factors

Scientific method: Statistical errors

(2014) Regina Nuzzo   NATURE

The Power of Meta-Analysis in Genome-Wide Association Studies

(2013) Orestis A. Panagiotou et al.   Annual Review of Genomics and Human Genetics

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

A Small Molecule Inhibitor of Src Family Kinases Promotes Simple Epithelial Differentiation of Human Pluripotent Stem Cells

(2013) Xiaojun Lian et al.   PLoS One

Analysis and Prediction of Pathways in HeLa Cells by Integrating Biological Levels of Organization with Systems-Biology Approaches

(2013) Juan Carlos Higareda-Almaraz et al.   PLoS One

A Genome-Wide Association Study of Total Serum and Mite-Specific IgEs in Asthma Patients

(2013) Jeong-Hyun Kim et al.   PLoS One

The limits of p-values for biological data mining

(2013) James D Malley et al.   BioData Mining

ToxPi GUI: an interactive visualization tool for transparent integration of data from diverse sources of evidence

(2012) D. M. Reif et al.   BIOINFORMATICS

Genome-wide association study indicates two novel resistance loci for severe malaria

(2012) Christian Timmann et al.   NATURE

Correcting Away the Hidden Heritability

(2011) Scott M. Williams et al.   ANNALS OF HUMAN GENETICS

Prioritization of Epilepsy Associated Candidate Genes by Convergent Analysis

(2011) Peilin Jia et al.   PLoS One

Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data

(2010) David M. Reif et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Limited Systemic Sclerosis Patients with Pulmonary Arterial Hypertension Show Biomarkers of Inflammation and Vascular Injury

(2010) Sarah A. Pendergrass et al.   PLoS One

Shadows of complexity: what biological networks reveal about epistasis and pleiotropy

(2009) Anna L. Tyler et al.   BIOESSAYS

Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci

(2009) et al.   HUMAN MOLECULAR GENETICS

Genome-wide and fine-resolution association analysis of malaria in West Africa

(2009) Muminatou Jallow et al.   NATURE GENETICS

Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture

(2009) Casey S. Greene et al.   PLoS One

Melanism in Peromyscus Is Caused by Independent Mutations in Agouti

(2009) Evan P. Kingsley et al.   PLoS One

Reducing the probability of false positive research findings by pre-publication validation – Experience with a large multiple sclerosis database

(2008) Martin Daumer et al.   BMC Medical Research Methodology

Curses—Winnerʼs and Otherwise—in Genetic Epidemiology

(2008) Peter Kraft   EPIDEMIOLOGY

Estimation of significance thresholds for genomewide association scans

(2008) Frank Dudbridge et al.   GENETIC EPIDEMIOLOGY

What Do We Mean by ‘Replication’ and ‘Validation’ in Genome-Wide Association Studies?

(2008) Bernd-Wolfgang Igl et al.   HUMAN HEREDITY

Genomic convergence to identify candidate genes for Alzheimer Disease on chromosome 10

(2008) Xueying Liang et al.   HUMAN MUTATION

Is Replication the Gold Standard for Validating Genome-Wide Association Findings?

(2008) Yong-Jun Liu et al.   PLoS One