High-throughput microfluidics to control and measure signaling dynamics in single yeast cells

How to train your microbe: methods for dynamically characterizing gene networks

(2015) Sebastian M Castillo-Hair et al.   CURRENT OPINION IN MICROBIOLOGY

Chemical Biology Strategies for Posttranslational Control of Protein Function

(2014) Rishi Rakhit et al.   CHEMISTRY & BIOLOGY

Encoding of Temporal Signals by the TGF-β Pathway and Implications for Embryonic Patterning

(2014) Benoit Sorre et al.   DEVELOPMENTAL CELL

Research highlights: microfluidics meets big data

(2014) Peter Tseng et al.   LAB ON A CHIP

Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast

(2014) Brian M. Zid et al.   NATURE

Rapid and tunable post-translational coupling of genetic circuits

(2014) Arthur Prindle et al.   NATURE

The present and future role of microfluidics in biomedical research

(2014) Eric K. Sackmann et al.   NATURE

Advances in fluorescence labeling strategies for dynamic cellular imaging

(2014) Kevin M Dean et al.   Nature Chemical Biology

Scalable inference of heterogeneous reaction kinetics from pooled single-cell recordings

(2014) Christoph Zechner et al.   NATURE METHODS

High-throughput microfluidic single-cell analysis pipeline for studies of signaling dynamics

(2014) Ryan A Kellogg et al.   Nature Protocols

A Microfluidic System for Studying Ageing and Dynamic Single-Cell Responses in Budding Yeast

(2014) Matthew M. Crane et al.   PLoS One

Nucleocytoplasmic Shuttling of a GATA Transcription Factor Functions as a Development Timer

(2014) H. Cai et al.   SCIENCE

Accurate information transmission through dynamic biochemical signaling networks

(2014) J. Selimkhanov et al.   SCIENCE

In-Vivo Real-Time Control of Protein Expression from Endogenous and Synthetic Gene Networks

(2014) Filippo Menolascina et al.   PLoS Computational Biology

Encoding and Decoding Cellular Information through Signaling Dynamics

(2013) Jeremy E. Purvis et al.   CELL

Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses

(2013) Natalia Petrenko et al.   MOLECULAR BIOLOGY OF THE CELL

Using Spinach-based sensors for fluorescence imaging of intracellular metabolites and proteins in living bacteria

(2013) Rita L Strack et al.   Nature Protocols

Construction and use of a microfluidic dissection platform for long-term imaging of cellular processes in budding yeast

(2013) Daphne H E W Huberts et al.   Nature Protocols

An Algorithm to Automate Yeast Segmentation and Tracking

(2013) Andreas Doncic et al.   PLoS One

A chemostat array enables the spatio-temporal analysis of the yeast proteome

(2013) N. Denervaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Determinants and Cellular Constraints in Noisy Gene Expression

(2013) A. Sanchez et al.   SCIENCE

Functional Roles of Pulsing in Genetic Circuits

(2013) J. H. Levine et al.   SCIENCE

Tunable Signal Processing Through Modular Control of Transcription Factor Translocation

(2013) N. Hao et al.   SCIENCE

Oscillatory Control of Factors Determining Multipotency and Fate in Mouse Neural Progenitors

(2013) I. Imayoshi et al.   SCIENCE

Molecular phenotyping of aging in single yeast cells using a novel microfluidic device

(2012) Zhengwei Xie et al.   AGING CELL

Quantitative Analysis of Molecular Absorption into PDMS Microfluidic Channels

(2012) Jack D. Wang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Chemical Genetic-Mediated Spatial Regulation of Protein Expression in Neurons Reveals an Axonal Function for WldS

(2012) Michael S. Cohen et al.   CHEMISTRY & BIOLOGY

Dynamic Response Diversity of NFAT Isoforms in Individual Living Cells

(2012) Nissan Yissachar et al.   MOLECULAR CELL

Single Cell Analysis of Yeast Replicative Aging Using a New Generation of Microfluidic Device

(2012) Yi Zhang et al.   PLoS One

Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform

(2012) S. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-term model predictive control of gene expression at the population and single-cell levels

(2012) J. Uhlendorf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorescence Imaging of Cellular Metabolites with RNA

(2012) Jeremy S. Paige et al.   SCIENCE

Fast-acting and nearly gratuitous induction of gene expression and protein depletion in Saccharomyces cerevisiae

(2011) R. Scott McIsaac et al.   MOLECULAR BIOLOGY OF THE CELL

Stimulus-dependent dynamics of p53 in single cells

(2011) E. Batchelor et al.   Molecular Systems Biology

Bright and stable near-infrared fluorescent protein for in vivo imaging

(2011) Grigory S Filonov et al.   NATURE BIOTECHNOLOGY

Optical sensors for measuring dynamic changes of cytosolic metabolite levels in yeast

(2011) Clara Bermejo et al.   Nature Protocols

Signal-dependent dynamics of transcription factor translocation controls gene expression

(2011) Nan Hao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Understanding the temporal codes of intra-cellular signals

(2010) Marcelo Behar et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Measurement of single-cell dynamics

(2010) David G. Spiller et al.   NATURE

Soft lithography for micro- and nanoscale patterning

(2010) Dong Qin et al.   Nature Protocols

Glucose regulates transcription in yeast through a network of signaling pathways

(2009) Shadia Zaman et al.   Molecular Systems Biology

Microfluidic devices for measuring gene network dynamics in single cells

(2009) Matthew R. Bennett et al.   NATURE REVIEWS GENETICS

Tracking lineages of single cells in lines using a microfluidic device

(2009) A. C. Rowat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic analysis of MAPK signaling using a high-throughput microfluidic single-cell imaging platform

(2009) R. J. Taylor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A microfluidic system for dynamic yeast cell imaging

(2008) Philip J. Lee et al.   BIOTECHNIQUES

A Chemical Genomics Study Identifies Snf1 as a Repressor ofGCN4Translation

(2008) Margaret K. Shirra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Anchor-Away Technique: Rapid, Conditional Establishment of Yeast Mutant Phenotypes

(2008) Hirohito Haruki et al.   MOLECULAR CELL

Regulation of Cell Signaling Dynamics by the Protein Kinase-Scaffold Ste5

(2008) Nan Hao et al.   MOLECULAR CELL

Metabolic gene regulation in a dynamically changing environment

(2008) Matthew R. Bennett et al.   NATURE

Frequency-modulated nuclear localization bursts coordinate gene regulation

(2008) Long Cai et al.   NATURE

Signal processing by the HOG MAP kinase pathway

(2008) P. Hersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Frequency Dependence of Osmo-Adaptation in Saccharomyces cerevisiae

(2008) J. T. Mettetal et al.   SCIENCE

A small molecule-directed approach to control protein localization and function

(2008) Prasanthi Geda et al.   YEAST