Genetic Determinants and Cellular Constraints in Noisy Gene Expression

Regulation of Noise in Gene Expression

(2013) Alvaro Sanchez et al.   Annual Review of Biophysics

Precise Developmental Gene Expression Arises from Globally Stochastic Transcriptional Activity

(2013) Shawn C. Little et al.   CELL

Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise

(2013) M. Dadiani et al.   GENOME RESEARCH

Eukaryotic transcriptional dynamics: from single molecules to cell populations

(2013) Antoine Coulon et al.   NATURE REVIEWS GENETICS

Rapid Transcription Fosters Coordinate snail Expression in the Drosophila Embryo

(2013) Alistair Nicol Boettiger et al.   Cell Reports

Promoter Sequence Determines the Relationship between Expression Level and Noise

(2013) Lucas B. Carey et al.   PLOS BIOLOGY

Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression

(2013) C. J. Zopf et al.   PLoS Computational Biology

Noise-mean relationship in mutated promoters

(2012) G. Hornung et al.   GENOME RESEARCH

Universal Protein Fluctuations in Populations of Microorganisms

(2012) Hanna Salman et al.   PHYSICAL REVIEW LETTERS

Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation

(2012) T. Muramoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional burst frequency and burst size are equally modulated across the human genome

(2012) R. D. Dar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-molecule transcript counting of stem-cell markers in the mouse intestine

(2011) Shalev Itzkovitz et al.   NATURE CELL BIOLOGY

General properties of transcriptional time series in Escherichia coli

(2011) Lok-hang So et al.   NATURE GENETICS

Mammalian Genes Are Transcribed with Widely Different Bursting Kinetics

(2011) D. M. Suter et al.   SCIENCE

Real-Time Observation of Transcription Initiation and Elongation on an Endogenous Yeast Gene

(2011) D. R. Larson et al.   SCIENCE

Effect of Promoter Architecture on the Cell-to-Cell Variability in Gene Expression

(2011) Alvaro Sanchez et al.   PLoS Computational Biology

Nucleosome-Depleted Regions in Cell-Cycle-Regulated Promoters Ensure Reliable Gene Expression in Every Cell Cycle

(2010) Lu Bai et al.   DEVELOPMENTAL CELL

Non-genetic heterogeneity from stochastic partitioning at cell division

(2010) Dann Huh et al.   NATURE GENETICS

Single-allele analysis of transcription kinetics in living mammalian cells

(2010) Sharon Yunger et al.   NATURE METHODS

Transcription of functionally related constitutive genes is not coordinated

(2010) Saumil J Gandhi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tuning and controlling gene expression noise in synthetic gene networks

(2010) Kevin F. Murphy et al.   NUCLEIC ACIDS RESEARCH

Noise Can Induce Bimodality in Positive Transcriptional Feedback Loops Without Bistability

(2010) T.-L. To et al.   SCIENCE

Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells

(2010) Y. Taniguchi et al.   SCIENCE

HIV Promoter Integration Site Primarily Modulates Transcriptional Burst Size Rather Than Frequency

(2010) Ron Skupsky et al.   PLoS Computational Biology

Visualization of Individual Scr mRNAs during Drosophila Embryogenesis Yields Evidence for Transcriptional Bursting

(2009) Adam Paré et al.   CURRENT BIOLOGY

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Two strategies for gene regulation by promoter nucleosomes

(2008) I. Tirosh et al.   GENOME RESEARCH

Single-RNA counting reveals alternative modes of gene expression in yeast

(2008) Daniel Zenklusen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Stochastic Single-Molecule Event Triggers Phenotype Switching of a Bacterial Cell

(2008) P. J. Choi et al.   SCIENCE

Distinct Modes of Regulation by Chromatin Encoded through Nucleosome Positioning Signals

(2008) Yair Field et al.   PLoS Computational Biology