High-throughput microfluidic single-cell analysis pipeline for studies of signaling dynamics

Microfluidic single-cell analysis for systems immunology

(2014) Michael Junkin et al.   LAB ON A CHIP

Flow-switching allows independently programmable, extremely stable, high-throughput diffusion-based gradients

(2013) Tino Frank et al.   LAB ON A CHIP

Optogenetic protein clustering and signaling activation in mammalian cells

(2013) Lukasz J Bugaj et al.   NATURE METHODS

Quantifying the transcriptional output of single alleles in single living mammalian cells

(2013) Sharon Yunger et al.   Nature Protocols

Counting molecules in single organelles with superresolution microscopy allows tracking of the endosome maturation trajectory

(2013) E. M. Puchner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic measurement of memory B-cell recall using antibody repertoire sequencing

(2013) C. Vollmers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineers are from PDMS-land, Biologists are from Polystyrenia

(2012) Erwin Berthier et al.   LAB ON A CHIP

Microfluidic sorting of arbitrary cells with dynamic optical tweezers

(2012) Benjamin Landenberger et al.   LAB ON A CHIP

Vacuum-assisted cell loading enables shear-free mammalian microfluidic culture

(2012) Martin Kolnik et al.   LAB ON A CHIP

Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals

(2012) John G. Albeck et al.   MOLECULAR CELL

Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns

(2012) Veronica Sanchez-Freire et al.   Nature Protocols

Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation

(2012) T. Muramoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Migration of cells in a social context

(2012) S. Vedel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes

(2012) S.-H. Shim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Decade of Imaging Cellular Motility and Interaction Dynamics in the Immune System

(2012) R. N. Germain et al.   SCIENCE

Imaging Single-Cell Signaling Dynamics with a Deterministic High-Density Single-Cell Trap Array

(2011) Kwanghun Chung et al.   ANALYTICAL CHEMISTRY

In silico feedback for in vivo regulation of a gene expression circuit

(2011) Andreas Milias-Argeitis et al.   NATURE BIOTECHNOLOGY

High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays

(2011) Véronique Lecault et al.   NATURE METHODS

Single-cell genomics

(2011) Tomer Kalisky et al.   NATURE METHODS

Information Transduction Capacity of Noisy Biochemical Signaling Networks

(2011) R. Cheong et al.   SCIENCE

Organization of Intracellular Reactions with Rationally Designed RNA Assemblies

(2011) C. J. Delebecque et al.   SCIENCE

Measurement of single-cell dynamics

(2010) David G. Spiller et al.   NATURE

Single-cell NF-κB dynamics reveal digital activation and analogue information processing

(2010) Savaş Tay et al.   NATURE

Soft lithography for micro- and nanoscale patterning

(2010) Dong Qin et al.   Nature Protocols

Microfluidic single cell arrays to interrogate signalling dynamics of individual, patient-derived hematopoietic stem cells

(2009) Shannon L. Faley et al.   LAB ON A CHIP

Spatiotemporal control of cell signalling using a light-switchable protein interaction

(2009) Anselm Levskaya et al.   NATURE

Using a Microfluidic Device for High-Content Analysis of Cell Signaling

(2009) R. Cheong et al.   Science Signaling

Suppression of LPS-Induced TNF-  Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105

(2009) E. A. Wall et al.   Science Signaling

High Content Cell Screening in a Microfluidic Device

(2008) Raymond Cheong et al.   MOLECULAR & CELLULAR PROTEOMICS

Frequency-modulated nuclear localization bursts coordinate gene regulation

(2008) Long Cai et al.   NATURE

Fluorescent probes for super-resolution imaging in living cells

(2008) Marta Fernández-Suárez et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY