Opportunities for drug repositioning from phenome-wide association studies

BalestraWeb: efficient online evaluation of drug-target interactions

(2014) M. C. Cobanoglu et al.   BIOINFORMATICS

Genomics-Enabled Drug Repositioning and Repurposing

(2014) Aidan Power et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

An overview of MetaMap: historical perspective and recent advances

(2014) Alan R Aronson et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Adverse Drug Reaction Prediction Using Scores Produced by Large-Scale Drug-Protein Target Docking on High-Performance Computing Machines

(2014) Montiago X. LaBute et al.   PLoS One

In Silicotarget fishing: addressing a “Big Data” problem by ligand-based similarity rankings with data fusion

(2014) Xian Liu et al.   Journal of Cheminformatics

The challenges, advantages and future of phenome-wide association studies

(2013) Scott J. Hebbring   IMMUNOLOGY

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

(2013) Joshua C Denny et al.   NATURE BIOTECHNOLOGY

Rational drug repositioning by medical genetics

(2013) Zhong-Yi Wang et al.   NATURE BIOTECHNOLOGY

DGIdb: mining the druggable genome

(2013) Malachi Griffith et al.   NATURE METHODS

Validating therapeutic targets through human genetics

(2013) Robert M. Plenge et al.   NATURE REVIEWS DRUG DISCOVERY

DrugBank 4.0: shedding new light on drug metabolism

(2013) Vivian Law et al.   NUCLEIC ACIDS RESEARCH

Challenges and opportunities of drug repositioning

(2013) Natalia Novac   TRENDS IN PHARMACOLOGICAL SCIENCES

SemMedDB: a PubMed-scale repository of biomedical semantic predications

(2012) H. Kilicoglu et al.   BIOINFORMATICS

Use of genome-wide association studies for drug repositioning

(2012) Philippe Sanseau et al.   NATURE BIOTECHNOLOGY