标题
An atomic structure of human γ-secretase
作者
关键词
-
出版物
NATURE
Volume 525, Issue 7568, Pages 212-217
出版商
Springer Nature
发表日期
2015-08-18
DOI
10.1038/nature14892
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cooperative Roles of Hydrophilic Loop 1 and the C-Terminus of Presenilin 1 in the Substrate-Gating Mechanism of -Secretase
- (2015) S. Takagi-Niidome et al. JOURNAL OF NEUROSCIENCE
- Semi-automated selection of cryo-EM particles in RELION-1.3
- (2015) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH
- (2015) Shangyu Dang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis of human γ-secretase assembly
- (2015) Linfeng Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions
- (2015) Alan Brown et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Lessons from a Failed γ-Secretase Alzheimer Trial
- (2014) Bart De Strooper CELL
- The dynamic conformational landscape of -secretase
- (2014) N. Elad et al. JOURNAL OF CELL SCIENCE
- Three-dimensional structure of human γ-secretase
- (2014) Peilong Lu et al. NATURE
- Crystal structure of the γ-secretase component nicastrin
- (2014) Tian Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of the Yeast Mitochondrial Large Ribosomal Subunit
- (2014) A. Amunts et al. SCIENCE
- Beam-induced motion correction for sub-megadalton cryo-EM particles
- (2014) Sjors HW Scheres eLife
- Conformation-independent structural comparison of macromolecules withProSMART
- (2014) Robert A. Nicholls et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The role of protein glycosylation in Alzheimer disease
- (2013) Sophia Schedin-Weiss et al. FEBS Journal
- Nicastrin Overexpression in Transgenic Mice Induces Aberrant Behavior and APP Processing
- (2013) Jun Seo Goo et al. MOLECULAR NEUROBIOLOGY
- Quantifying the local resolution of cryo-EM density maps
- (2013) Alp Kucukelbir et al. NATURE METHODS
- Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM
- (2013) Xueming Li et al. NATURE METHODS
- Structural Interactions between Inhibitor and Substrate Docking Sites Give Insight into Mechanisms of Human PS1 Complexes
- (2013) Yi Li et al. STRUCTURE
- High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
- (2013) Shaoxia Chen et al. ULTRAMICROSCOPY
- Presenilins and -Secretase: Structure, Function, and Role in Alzheimer Disease
- (2013) B. De Strooper et al. Cold Spring Harbor Perspectives in Medicine
- Peptides based on the presenilin-APP binding domain inhibit APP processing and Aβ production through interfering with the APP transmembrane domain
- (2012) Cary Esselens et al. FASEB JOURNAL
- Contribution of the γ-Secretase Subunits to the Formation of Catalytic Pore of Presenilin 1 Protein
- (2012) Koji Takeo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Structure of a presenilin family intramembrane aspartate protease
- (2012) Xiaochun Li et al. NATURE
- Twenty years of Alzheimer’s disease-causing mutations
- (2011) Alison Goate et al. JOURNAL OF NEUROCHEMISTRY
- APH1 Polar Transmembrane Residues Regulate the Assembly and Activity of Presenilin Complexes
- (2009) Raphaëlle Pardossi-Piquard et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glu-333 of Nicastrin Directly Participates in γ-Secretase Activity
- (2009) Daniel R. Dries et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CHAINSAW: a program for mutating pdb files used as templates in molecular replacement
- (2008) Norman Stein JOURNAL OF APPLIED CRYSTALLOGRAPHY
- The C-Terminal PAL Motif and Transmembrane Domain 9 of Presenilin 1 Are Involved in the Formation of the Catalytic Pore of the -Secretase
- (2008) C. Sato et al. JOURNAL OF NEUROSCIENCE
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