Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine’s Tool Box
出版年份 2015 全文链接
标题
Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine’s Tool Box
作者
关键词
-
出版物
MOLECULES
Volume 20, Issue 9, Pages 16852-16891
出版商
MDPI AG
发表日期
2015-09-16
DOI
10.3390/molecules200916852
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Hybrid Paclitaxel and Gold Nanorod-Loaded Human Serum Albumin Nanoparticles for Simultaneous Chemotherapeutic and Photothermal Therapy on 4T1 Breast Cancer Cells
- (2015) Donna V. Peralta et al. ACS Applied Materials & Interfaces
- Coumarin: A Promising Scaffold for Anticancer Agents
- (2015) Manjinder Kaur et al. Anti-Cancer Agents in Medicinal Chemistry
- Design, synthesis, and biological evaluation of benzofuran- and 2,3-dihydrobenzofuran-2-carboxylic acid N-(substituted)phenylamide derivatives as anticancer agents and inhibitors of NF-κB
- (2015) Minho Choi et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Nanotechnological carriers for cancer chemotherapy: The state of the art
- (2015) Marilene Estanqueiro et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Recent advances in dendrimer-based nanovectors for tumor-targeted drug and gene delivery
- (2015) Prashant Kesharwani et al. DRUG DISCOVERY TODAY
- Dinutuximab: First Global Approval
- (2015) Sohita Dhillon DRUGS
- Bioactive Benzofuran derivatives: A review
- (2015) Hena Khanam et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives
- (2015) Chris Sherer et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy
- (2015) Edgar Pérez-Herrero et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications
- (2015) Andreas Wicki et al. JOURNAL OF CONTROLLED RELEASE
- Nivolumab: another weapon in the growing immunotherapy arsenal
- (2015) Gerald Falchook LANCET ONCOLOGY
- Nivolumab in Previously Untreated Melanoma without BRAF Mutation
- (2015) Caroline Robert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cancer nanomedicine: from targeted delivery to combination therapy
- (2015) Xiaoyang Xu et al. TRENDS IN MOLECULAR MEDICINE
- Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth
- (2015) Ningning Liu et al. Oncotarget
- Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy
- (2014) Ravi V. J. Chari et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis and In Vitro Antiproliferative Activity of Thiazole-Based Nitrogen Mustards: The Hydrogen Bonding Interaction between Model Systems and Nucleobases
- (2014) Krzysztof Laczkowski et al. Anti-Cancer Agents in Medicinal Chemistry
- Novel Action and Mechanism of Auranofin in Inhibition of Vascular Endothelial Growth Factor Receptor-3-Dependent Lymphangiogenesis
- (2014) Xiaodong Chen et al. Anti-Cancer Agents in Medicinal Chemistry
- Antibody drug conjugates
- (2014) Beverly A. Teicher CURRENT OPINION IN ONCOLOGY
- Synthesis of novel 1,2,4-triazoles, triazolothiadiazines and triazolothiadiazoles as potential anticancer agents
- (2014) Mona M. Kamel et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of novel building blocks of benzosuberone bearing coumarin moieties and their evaluation as potential anticancer agents
- (2014) Bandi Yadagiri et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, characterization and anti-proliferative activity of heterocyclic hypervalent organoantimony compounds
- (2014) Yi Chen et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53
- (2014) SEE-HYOUN G PARK et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Design, Synthesis, and Structure–Activity Relationship Studies of Novel Fused Heterocycles-Linked Triazoles with Good Activity and Water Solubility
- (2014) Xufeng Cao et al. JOURNAL OF MEDICINAL CHEMISTRY
- 1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells
- (2014) Sergio Valente et al. JOURNAL OF MEDICINAL CHEMISTRY
- Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
- (2014) Edon Vitaku et al. JOURNAL OF MEDICINAL CHEMISTRY
- Thiosulfoxide (Sulfane) Sulfur: New Chemistry and New Regulatory Roles in Biology
- (2014) John Toohey et al. MOLECULES
- Just so stories: The random acts of anti-cancer nanomedicine performance
- (2014) Seyed Moein Moghimi et al. Nanomedicine-Nanotechnology Biology and Medicine
- Drug delivery: Beyond active tumour targeting
- (2014) Sharon M. Sagnella et al. Nanomedicine-Nanotechnology Biology and Medicine
- Cytotoxicity of carbon nanotube variants: A comparativein vitroexposure study with A549 epithelial and J774 macrophage cells
- (2014) Prem Kumarathasan et al. Nanotoxicology
- Imidazole derivatives show anticancer potential by inducing apoptosis and cellular senescence
- (2014) Gangavaram V. M. Sharma et al. MedChemComm
- Synthesis of a novel series of 2,3,4-trisubstituted oxazolidines designed by isosteric replacement or rigidification of the structure and cytotoxic evaluation
- (2014) Saulo F. Andrade et al. MedChemComm
- Synthesis, Antibacterial, and Antiviral Evaluation of New Heterocycles Containing the Pyridine Moiety
- (2013) Marwa S. Salem et al. ARCHIV DER PHARMAZIE
- Salvage Chemotherapy in Recurrent Platinum-Resistant or Refractory Epithelial Ovarian Cancer with Carboplatin and Distearoylphosphatidylcholine Pegylated Liposomal Doxorubicin (Lipo-Dox®)
- (2013) Nipon Khemapech et al. Asian Pacific Journal of Cancer Prevention
- Mefloquine-Oxazolidine Derivatives: A New Class of Anticancer Agents
- (2013) Felipe A. R. Rodrigues et al. Chemical Biology & Drug Design
- Synthesis, reactions and biological activity of some new bis-heterocyclic ring compounds containing sulphur atom
- (2013) Yahia Mabkhot et al. Chemistry Central Journal
- Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors
- (2013) P. Vrignaud et al. CLINICAL CANCER RESEARCH
- Triazolothiadiazoles and triazolothiadiazines – Biologically attractive scaffolds
- (2013) Imtiaz Khan et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Biofabrication of gold nanoparticles and its biocompatibility in human breast adenocarcinoma cells (MCF-7)
- (2013) Muralidharan Murugan et al. JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
- Two schedules of etirinotecan pegol (NKTR-102) in patients with previously treated metastatic breast cancer: a randomised phase 2 study
- (2013) Ahmad Awada et al. LANCET ONCOLOGY
- Site-specific antibody drug conjugates for cancer therapy
- (2013) Siler Panowski et al. mAbs
- Chemistry and Biology of Indoles and Indazoles: A Mini-Review
- (2013) Nasir Shafakat Ali et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Biomedical Importance of Indoles
- (2013) Nagendra Kaushik et al. MOLECULES
- Synthesis and Antibacterial Evaluation of Novel Heterocyclic Compounds Containing a Sulfonamido Moiety
- (2013) Mohammad Azab et al. MOLECULES
- Shaping cancer nanomedicine: the effect of particle shape on the in vivo journey of nanoparticles
- (2013) Randall Toy et al. Nanomedicine
- Nanomaterials in combating cancer: Therapeutic applications and developments
- (2013) Samina Nazir et al. Nanomedicine-Nanotechnology Biology and Medicine
- Gold-nanobeacons for gene therapy: evaluation of genotoxicity, cell toxicity and proteome profiling analysis
- (2013) João Conde et al. Nanotoxicology
- Antibody–drug conjugates
- (2013) Rachel S. Zolot et al. NATURE REVIEWS DRUG DISCOVERY
- The PI3-Kinase Delta Inhibitor Idelalisib (GS-1101) Targets Integrin-Mediated Adhesion of Chronic Lymphocytic Leukemia (CLL) Cell to Endothelial and Marrow Stromal Cells
- (2013) Stefania Fiorcari et al. PLoS One
- Antibody–drug conjugates:
- (2013) Stephen Ornes PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents
- (2013) Narsimha Reddy Penthala et al. MedChemComm
- The emerging role of ibrutinib in the treatment of chronic lymphocytic leukemia
- (2013) Stefano Molica Expert Review of Hematology
- Synthesis, anti-inflammatory, analgesic and anticonvulsant activities of some new 4,6-dimethoxy-5-(heterocycles)benzofuran starting from naturally occurring visnagin
- (2013) E.R. El-Sawy et al. Arabian Journal of Chemistry
- Imidazole: Having Versatile Biological Activities
- (2013) Amita Verma et al. Journal of Chemistry
- Synthesis and Antimicrobial Activities of Some New Heterocyclic Compounds Based on 6-Chloropyridazine-3(2H)-thione
- (2013) Nasser M. Abd El-Salam et al. Journal of Chemistry
- Challenges in Development of Nanoparticle-Based Therapeutics
- (2012) Neil Desai AAPS Journal
- Design of Multifunctional Gold Nanoparticles for In Vitro and In Vivo Gene Silencing
- (2012) João Conde et al. ACS Nano
- Liposomal drug delivery systems: From concept to clinical applications
- (2012) Theresa M. Allen et al. ADVANCED DRUG DELIVERY REVIEWS
- 1,2,4-Oxadiazoles: A new class of anti-prostate cancer agents
- (2012) Gopal L. Khatik et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Benzimidazole bearing oxadiazole and triazolo-thiadiazoles nucleus: Design and synthesis as anticancer agents
- (2012) Asif Husain et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Antibody-Drug Conjugates for the Treatment of Cancer
- (2012) John A. Flygare et al. Chemical Biology & Drug Design
- The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy
- (2012) Tennyson L. Doane et al. CHEMICAL SOCIETY REVIEWS
- Heterocycles in drugs and drug discovery
- (2012) A. Gomtsyan Chemistry of Heterocyclic Compounds
- Nanotechnology-based combinational drug delivery: an emerging approach for cancer therapy
- (2012) Priyambada Parhi et al. DRUG DISCOVERY TODAY
- Synthesis and antitumor evaluation of novel Benzo[d]pyrrolo[2,1-b]thiazole derivatives
- (2012) Ravi Chaniyara et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Benzimidazole clubbed with triazolo-thiadiazoles and triazolo-thiadiazines: New anticancer agents
- (2012) Asif Husain et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Coumarin-based drugs: a patent review (2008 – present)
- (2012) Christos Kontogiorgis et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Eribulin mesylate pharmacokinetics in patients with solid tumors receiving repeated oral ketoconazole
- (2012) L. A. Devriese et al. INVESTIGATIONAL NEW DRUGS
- Anticancer nanomedicine and tumor vascular permeability; Where is the missing link?
- (2012) Sebastien Taurin et al. JOURNAL OF CONTROLLED RELEASE
- Antibody–drug conjugates: Basic concepts, examples and future perspectives
- (2012) Giulio Casi et al. JOURNAL OF CONTROLLED RELEASE
- FDA's Approach to Regulation of Products of Nanotechnology
- (2012) M. A. Hamburg SCIENCE
- Size-dependent toxicity and cell interaction mechanisms of gold nanoparticles on mouse fibroblasts
- (2012) Rosella Coradeghini et al. TOXICOLOGY LETTERS
- Synthesis, antimicrobial and anticancer activities of some new N-methylsulphonyl and N-benzenesulphonyl-3-indolyl heterocycles
- (2012) Eslam Reda El-Sawy et al. Arabian Journal of Chemistry
- Nanoparticle Delivery of Cancer Drugs
- (2011) Andrew Z. Wang et al. Annual Review of Medicine
- The novel indole compound SK228 induces apoptosis and FAK/Paxillin disruption in tumor cell lines and inhibits growth of tumor graft in the nude mouse
- (2011) Sin-Ming Huang et al. INTERNATIONAL JOURNAL OF CANCER
- First-In-Man Study of CPX-351: A Liposomal Carrier Containing Cytarabine and Daunorubicin in a Fixed 5:1 Molar Ratio for the Treatment of Relapsed and Refractory Acute Myeloid Leukemia
- (2011) Eric J. Feldman et al. JOURNAL OF CLINICAL ONCOLOGY
- Albumin-based nanoparticles as potential controlled release drug delivery systems
- (2011) Ahmed O. Elzoghby et al. JOURNAL OF CONTROLLED RELEASE
- Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies
- (2011) Tore-Geir Iversen et al. Nano Today
- Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials
- (2011) Feng Zhao et al. Small
- Endocytosis of nanomedicines
- (2010) Gaurav Sahay et al. JOURNAL OF CONTROLLED RELEASE
- Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?
- (2010) Alaaldin M. Alkilany et al. JOURNAL OF NANOPARTICLE RESEARCH
- Intracellular uptake, transport, and processing of gold nanostructures
- (2010) Devika B. Chithrani MOLECULAR MEMBRANE BIOLOGY
- Physico-chemical features of engineered nanoparticles relevant to their toxicity
- (2010) Bice Fubini et al. Nanotoxicology
- Is Anticancer Drug Development Heading in the Right Direction?
- (2009) Trevor W. Hambley CANCER RESEARCH
- Development ofin vitrosystems for nanotoxicology: methodological considerations
- (2009) Vicki Stone et al. CRITICAL REVIEWS IN TOXICOLOGY
- Synthesis, antifungal activities and 3D-QSAR study of N-(5-substituted-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamides
- (2009) Xing-Hai Liu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Uptake and Intracellular Fate of Surface-Modified Gold Nanoparticles
- (2008) Paola Nativo et al. ACS Nano
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now