Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pick1 knockout mice

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

NMDA-receptor coagonists in serum, plasma, and cerebrospinal fluid of schizophrenia patients: A meta-analysis of case–control studies

(2013) Annelies Brouwer et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion

(2012) T M Ma et al.   MOLECULAR PSYCHIATRY

PICK1 expression in reactive astrocytes within the spinal cord of amyotrophic lateral sclerosis (ALS) rats

(2012) M. C. Focant et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment

(2011) Taku Nagai et al.   BEHAVIOURAL BRAIN RESEARCH

Acute d-serine treatment produces antidepressant-like effects in rodents

(2011) Oz Malkesman et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

PICK1 Loss of Function Occludes Homeostatic Synaptic Scaling

(2011) V. Anggono et al.   JOURNAL OF NEUROSCIENCE

Preserved Acute Pain and Impaired Neuropathic Pain in Mice Lacking Protein Interacting with C Kinase 1

(2011) Wei Wang et al.   Molecular Pain

Effects of low-dose d-serine on recognition and working memory in mice

(2011) Patricia Bado et al.   PSYCHOPHARMACOLOGY

Adolescent Onset of Cortical Disinhibition in Schizophrenia: Insights From Animal Models

(2011) P. O'Donnell   SCHIZOPHRENIA BULLETIN

Disruption of PICK1 attenuates the function of ASICs and PKC regulation of ASICs

(2010) Zhuang-Li Hu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Prenatal Interaction of Mutant DISC1 and Immune Activation Produces Adult Psychopathology

(2010) Bagrat Abazyan et al.   BIOLOGICAL PSYCHIATRY

Does subtle disturbance of neuronal migration contribute to schizophrenia and other neurodevelopmental disorders? Potential genetic mechanisms with possible treatment implications

(2010) Stephen I. Deutsch et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

PICK1 Regulates Incorporation of Calcium-Permeable AMPA Receptors during Cortical Synaptic Strengthening

(2010) R. L. Clem et al.   JOURNAL OF NEUROSCIENCE

Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders

(2010) Y Ayhan et al.   MOLECULAR PSYCHIATRY

Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits

(2010) Minae Niwa et al.   NEURON

A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: Altered l-serine level associated with disruption of PSAT1 gene expression

(2010) Yuji Ozeki et al.   NEUROSCIENCE RESEARCH

Spinal cord protein interacting with C kinase 1 is required for the maintenance of complete Freundʼs adjuvant-induced inflammatory pain but not for incision-induced post-operative pain

(2010) Fidelis E. Atianjoh et al.   PAIN

Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning

(2010) L. Volk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease

(2010) Austen J. Milnerwood et al.   TRENDS IN NEUROSCIENCES

Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood

(2009) Daisuke Ibi et al.   BEHAVIOURAL BRAIN RESEARCH

Neonatal Phencyclidine Treatment in Mice Induces Behavioral, Histological and Neurochemical Abnormalities in Adulthood

(2009) Akiko Nakatani-Pawlak et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Cortical Development and Glutamatergic Dysregulation in Schizophrenia

(2009) Akira Sawa   BIOLOGICAL PSYCHIATRY

Co-Administration of a D-Amino Acid Oxidase Inhibitor Potentiates the Efficacy of D-Serine in Attenuating Prepulse Inhibition Deficits After Administration of Dizocilpine

(2009) Kenji Hashimoto et al.   BIOLOGICAL PSYCHIATRY

PICK1 deficiency causes male infertility in mice by disrupting acrosome formation

(2009) Nan Xiao et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms underlying spontaneous patterned activity in developing neural circuits

(2009) Aaron G. Blankenship et al.   NATURE REVIEWS NEUROSCIENCE

Modulation of d-Serine Levels in Brains of Mice Lacking PICK1

(2008) Takatoshi Hikida et al.   BIOLOGICAL PSYCHIATRY

Sequential Generation of Two Distinct Synapse-Driven Network Patterns in Developing Neocortex

(2008) C. Allene et al.   JOURNAL OF NEUROSCIENCE

NMDA receptors in clinical neurology: excitatory times ahead

(2008) Lorraine V Kalia et al.   LANCET NEUROLOGY

Enlargement of the lateral ventricles in mutant DISC1 transgenic mice

(2008) M V Pletnikov et al.   MOLECULAR PSYCHIATRY

Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior

(2008) A C Basu et al.   MOLECULAR PSYCHIATRY

An Essential Role for PICK1 in NMDA Receptor-Dependent Bidirectional Synaptic Plasticity

(2008) Akira Terashima et al.   NEURON

Corequirement of PICK1 Binding and PKC Phosphorylation for Stable Surface Expression of the Metabotropic Glutamate Receptor mGluR7

(2008) Young Ho Suh et al.   NEURON