Acute d-serine treatment produces antidepressant-like effects in rodents

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

(2011) Nanxin Li et al.   BIOLOGICAL PSYCHIATRY

Bax inhibitor 1, a modulator of calcium homeostasis, confers affective resilience

(2011) Joshua G. Hunsberger et al.   BRAIN RESEARCH

A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department

(2011) Gregory Luke Larkin et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression

(2011) Lobna Ibrahim et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression

(2010) Nancy Diazgranados et al.   ARCHIVES OF GENERAL PSYCHIATRY

Strategies to Enhance N-Methyl-D-Aspartate Receptor-Mediated Neurotransmission in Schizophrenia, a Critical Review and Meta-Analysis

(2010) Guochuan Tsai et al.   CURRENT PHARMACEUTICAL DESIGN

Neuronal release of d-serine: a physiological pathway controlling extracellular d-serine concentration

(2010) Dina Rosenberg et al.   FASEB JOURNAL

D-serine signalling as a prominent determinant of neuronal-glial dialogue in the healthy and diseased brain

(2010) J.-M. Billard   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Rapid Resolution of Suicidal Ideation After a Single Infusion of anN-Methyl-D-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder

(2010) Nancy DiazGranados et al.   JOURNAL OF CLINICAL PSYCHIATRY

eIF2  Phosphorylation-Dependent Translation in CA1 Pyramidal Cells Impairs Hippocampal Memory Consolidation without Affecting General Translation

(2010) Z. Jiang et al.   JOURNAL OF NEUROSCIENCE

Post-weaning chronic social isolation produces profound behavioral dysregulation with decreases in prefrontal cortex synaptic-associated protein expression in female rats

(2010) Gretchen Hermes et al.   PHYSIOLOGY & BEHAVIOR

High dose D-serine in the treatment of schizophrenia

(2010) Joshua T. Kantrowitz et al.   SCHIZOPHRENIA RESEARCH

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain

(2010) Julia W. Cohen et al.   SYNAPSE

d-Serine exposure resulted in gene expression changes implicated in neurodegenerative disorders and neuronal dysfunction in male Fischer 344 rats

(2009) Molly E. Davidson et al.   ARCHIVES OF TOXICOLOGY

Effects of Intravenous Ketamine on Explicit and Implicit Measures of Suicidality in Treatment-Resistant Depression

(2009) Rebecca B. Price et al.   BIOLOGICAL PSYCHIATRY

The Female Urine Sniffing Test: A Novel Approach for Assessing Reward-Seeking Behavior in Rodents

(2009) Oz Malkesman et al.   BIOLOGICAL PSYCHIATRY

Reverse translational strategies for developing animal models of bipolar disorder

(2009) O. Malkesman et al.   Disease Models & Mechanisms

Pilot controlled trial of d-serine for the treatment of post-traumatic stress disorder

(2009) Uriel Heresco-Levy et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1)

(2009) Yogesh Dwivedi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia

(2009) Peixiong Yuan et al.   JOURNAL OF AFFECTIVE DISORDERS

Sequenced Treatment Alternatives to Relieve Depression (STAR*D): Lessons Learned

(2009) Sidney Zisook et al.   JOURNAL OF CLINICAL PSYCHIATRY

Glial Loss in the Prefrontal Cortex Is Sufficient to Induce Depressive-like Behaviors

(2008) Mounira Banasr et al.   BIOLOGICAL PSYCHIATRY

An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder

(2008) Sheldon H. Preskorn et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

The Behavioral and Neurochemical Effects of a Novel D-Amino Acid Oxidase Inhibitor Compound 8 [4H-Thieno [3,2-b]pyrrole-5-carboxylic Acid] and D-Serine

(2008) S. M. Smith et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole

(2008) M Banasr et al.   MOLECULAR PSYCHIATRY

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania

(2008) G Shaltiel et al.   MOLECULAR PSYCHIATRY

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE

Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

(2008) Gerard Sanacora et al.   NATURE REVIEWS DRUG DISCOVERY

Major Depressive Disorder

(2008) R.H. Belmaker et al.   NEW ENGLAND JOURNAL OF MEDICINE

BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments

(2008) S. Maeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

(2007) Sungho Maeng et al.   BIOLOGICAL PSYCHIATRY