Oxidative Stress, Disrupted Energy Metabolism, and Altered Signaling Pathways in Glutaryl-CoA Dehydrogenase Knockout Mice: Potential Implications of Quinolinic Acid Toxicity in the Neuropathology of Glutaric Acidemia Type I

The kynurenine pathway and neurodegenerative disease

(2015) Daniel C. Maddison et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases

(2014) Li Gan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Protective and restorative potency of Vitamin D on persistent biochemical autistic features induced in propionic acid-intoxicated rat pups

(2014) Hanan A Alfawaz et al.   BMC Complementary and Alternative Medicine

Kynurenines with Neuroactive and Redox Properties: Relevance to Aging and Brain Diseases

(2014) Jazmin Reyes Ocampo et al.   Oxidative Medicine and Cellular Longevity

Diabetes and the Brain: Oxidative Stress, Inflammation, and Autophagy

(2014) María Muriach et al.   Oxidative Medicine and Cellular Longevity

Increased Glutamate Receptor and Transporter Expression in the Cerebral Cortex and Striatum of Gcdh-/- Mice: Possible Implications for the Neuropathology of Glutaric Acidemia Type I

(2014) Valeska Lizzi Lagranha et al.   PLoS One

JAK2 inhibition is neuroprotective and reduces astrogliosis after quinolinic acid striatal lesion in adult mice

(2013) Raffaela Silvestre Ignarro et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Early modulation of the transcription factor Nrf2 in rodent striatal slices by quinolinic acid, a toxic metabolite of the kynurenine pathway

(2013) A.L. Colín-González et al.   NEUROSCIENCE

Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets

(2013) Rafael Lugo-Huitrón et al.   Oxidative Medicine and Cellular Longevity

Chemical Modification of Lysozyme, Glucose 6-Phosphate Dehydrogenase, and Bovine Eye Lens Proteins Induced by Peroxyl Radicals: Role of Oxidizable Amino Acid Residues

(2012) Andrea Arenas et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Novel crosstalk between ERK MAPK and p38 MAPK leads to homocysteine-NMDA receptor-mediated neuronal cell death

(2012) Ranjana Poddar et al.   JOURNAL OF NEUROCHEMISTRY

Induction of oxidative stress in brain of glutaryl-CoA dehydrogenase deficient mice by acute lysine administration

(2012) Bianca Seminotti et al.   MOLECULAR GENETICS AND METABOLISM

Reduction of Na+, K+-ATPase activity and expression in cerebral cortex of glutaryl-CoA dehydrogenase deficient mice: A possible mechanism for brain injury in glutaric aciduria type I

(2012) Alexandre Umpierrez Amaral et al.   MOLECULAR GENETICS AND METABOLISM

Disruption of brain redox homeostasis in glutaryl-CoA dehydrogenase deficient mice treated with high dietary lysine supplementation

(2012) Bianca Seminotti et al.   MOLECULAR GENETICS AND METABOLISM

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

The unsolved puzzle of neuropathogenesis in glutaric aciduria type I

(2011) Paris Jafari et al.   MOLECULAR GENETICS AND METABOLISM

Neonatal Astrocyte Damage Is Sufficient to Trigger Progressive Striatal Degeneration in a Rat Model of Glutaric Acidemia-I

(2011) Silvia Olivera-Bravo et al.   PLoS One

Use of guidelines improves the neurological outcome in glutaric aciduria type I

(2010) Jana Heringer et al.   ANNALS OF NEUROLOGY

The Nrf2-ARE Pathway

(2010) Jeffrey A. Johnson et al.   Annals of the New York Academy of Sciences

Mouse model of encephalopathy and novel treatment strategies with substrate competition in glutaric aciduria type I

(2010) William J. Zinnanti et al.   MOLECULAR GENETICS AND METABOLISM

Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death

(2009) Ranjana Poddar et al.   JOURNAL OF NEUROCHEMISTRY

NRF2 Cysteine Residues Are Critical for Oxidant/Electrophile-Sensing, Kelch-Like ECH-Associated Protein-1-Dependent Ubiquitination-Proteasomal Degradation, and Transcription Activation

(2009) X. He et al.   MOLECULAR PHARMACOLOGY

Kinetic characterization of l-[3H]glutamate uptake inhibition and increase oxidative damage induced by glutaric acid in striatal synaptosomes of rats

(2008) Danieli Valnes Magni et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Pathogenesis of CNS involvement in disorders of amino and organic acid metabolism

(2008) S. Kölker et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Astrocytic proliferation and mitochondrial dysfunction induced by accumulated glutaric acidemia I (GAI) metabolites: Possible implications for GAI pathogenesis

(2008) Silvia Olivera et al.   NEUROBIOLOGY OF DISEASE

Hormetic Dietary Phytochemicals

(2008) Tae Gen Son et al.   NEUROMOLECULAR MEDICINE