Autophagy regulation in the development and treatment of breast cancer

Twist-BRD4 Complex: Potential Drug Target for Basal-like Breast Cancer

(2015) Jian Shi et al.   CURRENT PHARMACEUTICAL DESIGN

The Combination of Rapamycin and Resveratrol Blocks Autophagy and Induces Apoptosis in Breast Cancer Cells

(2015) Anya Alayev et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Synthesis of Improved Lysomotropic Autophagy Inhibitors

(2015) Tong Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and in Vitro Anticancer Activity of the First Class of Dual Inhibitors of REV-ERBβ and Autophagy

(2015) Esther Torrente et al.   JOURNAL OF MEDICINAL CHEMISTRY

Apoptosis, autophagy, necroptosis, and cancer metastasis

(2015) Zhenyi Su et al.   Molecular Cancer

Tyrosine kinase inhibitor Thiotanib targets Bcr-Abl and induces apoptosis and autophagy in human chronic myeloid leukemia cells

(2014) Jiajun Fan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Non-canonical autophagy: An exception or an underestimated form of autophagy?

(2014) Francesca Scarlatti et al.   Autophagy

Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells

(2014) Ugur Akar et al.   Autophagy

Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity

(2014) Michelle Cicchini et al.   Autophagy

Mollugin induces tumor cell apoptosis and autophagy via the PI3K/AKT/mTOR/p70S6K and ERK signaling pathways

(2014) Li Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy Inhibition by Sustained Overproduction of IL6 Contributes to Arsenic Carcinogenesis

(2014) Y. Qi et al.   CANCER RESEARCH

Epigenetic Regulation of EMT: The Snail Story

(2014) Yiwei Lin et al.   CURRENT PHARMACEUTICAL DESIGN

Autophagy Induction by Histone Deacetylase Inhibitors Inhibits HIV Type 1

(2014) Grant R. Campbell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclovirobuxine D Induces Autophagy-Associated Cell Death via the Akt/mTOR Pathway in MCF-7 Human Breast Cancer Cells

(2014) Jing Lu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Carnosol Induces ROS-Mediated Beclin1-Independent Autophagy and Apoptosis in Triple Negative Breast Cancer

(2014) Yusra Al Dhaheri et al.   PLoS One

Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer

(2014) N Hasima et al.   Cell Death & Disease

Enhancing Therapeutic Effects of Docetaxel-Loaded Dendritic Copolymer Nanoparticles by Co-Treatment with Autophagy Inhibitor on Breast Cancer

(2014) Xudong Zhang et al.   Theranostics

The Importance of Autophagy Regulation in Breast Cancer Development and Treatment

(2014) Joanna Magdalena Zarzynska   Biomed Research International

The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy

(2014) Mónika Lippai et al.   Biomed Research International

Autophagy

(2013) Amber N. Hale et al.   Autophagy

Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer

(2013) Chenfang Dong et al.   CANCER CELL

Autophagy and human diseases

(2013) Peidu Jiang et al.   CELL RESEARCH

Hyperactivation of Mammalian Target of Rapamycin Complex 1 (mTORC1) Promotes Breast Cancer Progression through Enhancing Glucose Starvation-induced Autophagy and Akt Signaling

(2013) Yongqiang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPARγ mediates the effects of WIN55,212-2, an synthetic cannabinoid, on the proliferation and apoptosis of the BEL-7402 hepatocarcinoma cells

(2013) Yuehui Hong et al.   MOLECULAR BIOLOGY REPORTS

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

(2012) Julia Romanov et al.   EMBO JOURNAL

Differential induction of autophagy in caspase-3/7 down-regulating and Bcl-2 overexpressing recombinant CHO cells subjected to sodium butyrate treatment

(2012) Jae Seong Lee et al.   JOURNAL OF BIOTECHNOLOGY

Randomized Phase III Placebo-Controlled Trial of Letrozole Plus Oral Temsirolimus As First-Line Endocrine Therapy in Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer

(2012) Antonio C. Wolff et al.   JOURNAL OF CLINICAL ONCOLOGY

Autophagic cell death: Loch Ness monster or endangered species?

(2011) Han-Ming Shen et al.   Autophagy

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cell death by autophagy: facts and apparent artefacts

(2011) D Denton et al.   CELL DEATH AND DIFFERENTIATION

Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

(2011) H. Wei et al.   GENES & DEVELOPMENT

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

(2011) Yoshihiro Inami et al.   JOURNAL OF CELL BIOLOGY

A Role for Autophagic Protein Beclin 1 Early in Lymphocyte Development

(2011) I. Arsov et al.   JOURNAL OF IMMUNOLOGY

The Multifaceted Roles of Autophagy in Tumors—Implications for Breast Cancer

(2011) Jayanta Debnath   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Autophagy as a target for anticancer therapy

(2011) Filip Janku et al.   Nature Reviews Clinical Oncology

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK

(2011) L. Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The significance of expression of autophagy-related gene Beclin, Bcl-2, and Bax in breast cancer tissues

(2011) Qing Yao et al.   TUMOR BIOLOGY

Glucosamine induces autophagic cell death through the stimulation of ER stress in human glioma cancer cells

(2010) Mi-Sun Hwang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ARP101, a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells

(2010) Yoon Kyung Jo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Involvement of caspase-9 in autophagy-mediated cell survival pathway

(2010) Hyo-Soon Jeong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

CH05-10, a novel indinavir analog, is a broad-spectrum antitumor agent that induces cell cycle arrest, apoptosis, endoplasmic reticulum stress and autophagy

(2010) Jianlan You et al.   CANCER SCIENCE

BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair

(2010) P. J. O'Donovan et al.   CARCINOGENESIS

Inflammation: A driving force speeds cancer metastasis

(2010) Yadi Wu et al.   CELL CYCLE

Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells

(2010) Agostino Marrazzo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chromosome band 17q21 in breast cancer: Significant association between beclin 1 loss and HER2/NEU amplification

(2010) Tiziana Negri et al.   GENES CHROMOSOMES & CANCER

Autophagy Regulates Keratin 8 Homeostasis in Mammary Epithelial Cells and in Breast Tumors

(2010) S. Kongara et al.   MOLECULAR CANCER RESEARCH

Triple-negative breast cancer: disease entity or title of convenience?

(2010) Lisa Carey et al.   Nature Reviews Clinical Oncology

Niclosamide Prevents the Formation of Large Ubiquitin-Containing Aggregates Caused by Proteasome Inhibition

(2010) Esther Gies et al.   PLoS One

Autophagy and Tumorigenesis

(2010) Srirupa Roy et al.   Seminars in Immunopathology

A novel Bcl-XLinhibitor Z36 that induces autophagic cell death in Hela cells

(2009) Jian Lin et al.   Autophagy

Autophagy facilitates the progression of ERα-positive breast cancer cells to antiestrogen resistance

(2009) Patricia V. Schoenlein et al.   Autophagy

Double Transgenic Mice Crossed GFP-LC3 Transgenic Mice With αMyHC-mCherry-LC3 Transgenic Mice Are a New and Useful Tool to Examine the Role of Autophagy in the Heart

(2009) Mai Terada et al.   CIRCULATION JOURNAL

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

(2009) Anne Simonsen et al.   JOURNAL OF CELL BIOLOGY

Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling

(2009) Aruna D. Balgi et al.   PLoS One

New insights of epithelial-mesenchymal transition in cancer metastasis

(2008) Yadi Wu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review

(2008) G Ruiz-Irastorza et al.   ANNALS OF THE RHEUMATIC DISEASES

Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization

(2008) M. A. Qadir et al.   BREAST CANCER RESEARCH AND TREATMENT

A Small Molecule Inhibitor of Isoprenylcysteine Carboxymethyltransferase Induces Autophagic Cell Death in PC3 Prostate Cancer Cells

(2008) Mei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance

(2008) J. S. Samaddar et al.   MOLECULAR CANCER THERAPEUTICS

Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral BCL-2 of Murine γ-Herpesvirus 68

(2008) Bonsu Ku et al.   PLoS Pathogens