Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity

ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelicBecn1loss

(2014) Fred Lozy et al.   Autophagy

Mutational Landscape of the Essential Autophagy Gene BECN1 in Human Cancers

(2014) Saurabh V. Laddha et al.   MOLECULAR CANCER RESEARCH

ATG proteins mediate efferocytosis and suppress inflammation in mammary involution

(2013) Irina Teplova et al.   Autophagy

EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance

(2013) Yongjie Wei et al.   CELL

Atg6 is required for multiple vesicle trafficking pathways and hematopoiesis in Drosophila

(2013) B. V. Shravage et al.   DEVELOPMENT

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

(2013) J. Y. Guo et al.   GENES & DEVELOPMENT

p53 status determines the role of autophagy in pancreatic tumour development

(2013) Mathias T. Rosenfeldt et al.   NATURE

FIP200 is required for maintenance and differentiation of postnatal neural stem cells

(2013) Chenran Wang et al.   NATURE NEUROSCIENCE

Association of Single Nucleotide Polymorphisms in Wnt Signaling Pathway Genes with Breast Cancer in Saudi Patients

(2013) Mohammad Saud Alanazi et al.   PLoS One

Autophagy Opposes p53-Mediated Tumor Barrier to Facilitate Tumorigenesis in a Model of PALB2-Associated Hereditary Breast Cancer

(2013) Y. Huo et al.   Cancer Discovery

Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E-Driven Lung Tumors

(2013) A. M. Strohecker et al.   Cancer Discovery

The development of denosumab for the treatment of diseases of bone loss and cancer-induced bone destruction

(2012) Carsten Goessl et al.   Annals of the New York Academy of Sciences

RANK Induces Epithelial-Mesenchymal Transition and Stemness in Human Mammary Epithelial Cells and Promotes Tumorigenesis and Metastasis

(2012) M. Palafox et al.   CANCER RESEARCH

Developmental pathways in colon cancer

(2012) Fred E. Bertrand et al.   CELL CYCLE

Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells

(2012) C Gong et al.   ONCOGENE

Wnt Signaling in Mammary Glands: Plastic Cell Fates and Combinatorial Signaling

(2012) C. M. Alexander et al.   Cold Spring Harbor Perspectives in Biology

The interplay between autophagy and ROS in tumorigenesis

(2012) Sameera Kongara et al.   Frontiers in Oncology

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

(2011) Junli Liu et al.   CELL

Autophagy and endocrine resistance in breast cancer

(2011) Katherine L Cook et al.   Expert Review of Anticancer Therapy

Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

(2011) H. Wei et al.   GENES & DEVELOPMENT

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

A Genomic Predictor of Response and Survival Following Taxane-Anthracycline Chemotherapy for Invasive Breast Cancer

(2011) Christos Hatzis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Adipocyte-secreted factors increase osteoblast proliferation and the OPG/RANKL ratio to influence osteoclast formation

(2011) Markus C. Kühn et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cells of origin in cancer

(2011) Jane E. Visvader   NATURE

Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer

(2011) W Bu et al.   ONCOGENE

A gene expression signature identifies two prognostic subgroups of basal breast cancer

(2010) Renaud Sabatier et al.   BREAST CANCER RESEARCH AND TREATMENT

β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation

(2010) Felipe C Geyer et al.   MODERN PATHOLOGY

Autophagy Regulates Keratin 8 Homeostasis in Mammary Epithelial Cells and in Breast Tumors

(2010) S. Kongara et al.   MOLECULAR CANCER RESEARCH

RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis

(2010) Eva Gonzalez-Suarez et al.   NATURE

Control of mammary stem cell function by steroid hormone signalling

(2010) Marie-Liesse Asselin-Labat et al.   NATURE

Progesterone induces adult mammary stem cell expansion

(2010) Purna A. Joshi et al.   NATURE

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

(2010) Daniel Schramek et al.   NATURE

The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse

(2009) Rodrigo Fernandez-Valdivia et al.   DEVELOPMENTAL BIOLOGY

The Mammary Progenitor Marker CD61/ 3 Integrin Identifies Cancer Stem Cells in Mouse Models of Mammary Tumorigenesis

(2008) F. Vaillant et al.   CANCER RESEARCH

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE