Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice

Coinhibitory Suppression of T Cell Activation by CD40 Protects Against Obesity and Adipose Tissue Inflammation in Mice

(2014) Dennis Wolf et al.   CIRCULATION

CD40-Mediated Maintenance of Immune Homeostasis in the Adipose Tissue Microenvironment

(2014) Z. Yi et al.   DIABETES

Immune Cell Crosstalk in Obesity: A Key Role for Costimulation?

(2014) T. Seijkens et al.   DIABETES

Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation

(2014) Antonios Chatzigeorgiou et al.   HEPATOLOGY

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

(2014) A. Chatzigeorgiou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance

(2013) Chang-An Guo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance

(2013) J. Zhong et al.   DIABETES

Adipose tissue and adipocyte dysregulation

(2013) M. Lafontan   DIABETES & METABOLISM

The immune cells in adipose tissue

(2013) A. W. Ferrante   DIABETES OBESITY & METABOLISM

CD40L Stimulates the Crosstalk Between Adipocytes and Inflammatory Cells

(2013) A. Chatzigeorgiou et al.   HORMONE AND METABOLIC RESEARCH

The role of innate immune cells in obese adipose tissue inflammation and development of insulin resistance

(2013) Triantafyllos Chavakis et al.   THROMBOSIS AND HAEMOSTASIS

Soluble CD40 Ligand in Morbidly Obese Patients

(2013) Juan A. Baena-Fustegueras et al.   JAMA Surgery

CD40–CD40L: Linking pancreatic, adipose tissue and vascular inflammation in type 2 diabetes and its complications

(2012) Tom Seijkens et al.   Diabetes & Vascular Disease Research

The adaptive immune system as a fundamental regulator of adipose tissue inflammation and insulin resistance

(2012) Shawn Winer et al.   IMMUNOLOGY AND CELL BIOLOGY

Immunological complications of obesity

(2012) Thirumala-Devi Kanneganti et al.   NATURE IMMUNOLOGY

The cellular and signaling networks linking the immune system and metabolism in disease

(2012) Olivia Osborn et al.   NATURE MEDICINE

Adaptive immunity in obesity and insulin resistance

(2012) Henrike Sell et al.   Nature Reviews Endocrinology

CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies

(2012) Dennis Wolf et al.   PLoS One

CD40L Deficiency Ameliorates Adipose Tissue Inflammation and Metabolic Manifestations of Obesity in Mice

(2011) Marjorie Poggi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adipose tissue recruitment of leukocytes

(2010) Emily K Anderson et al.   CURRENT OPINION IN LIPIDOLOGY

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

(2010) Esther Lutgens et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes

(2009) M. Poggi et al.   DIABETOLOGIA

The immunobiology of CD154–CD40–TRAF interactions in atherosclerosis

(2009) David Engel et al.   SEMINARS IN IMMUNOLOGY

The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling

(2008) M. M. P. C. Donners et al.   BLOOD

FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects

(2008) David Lagorce et al.   BMC BIOINFORMATICS