CD40-Mediated Maintenance of Immune Homeostasis in the Adipose Tissue Microenvironment

CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance

(2013) Chang-An Guo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Immunological Goings-on in Visceral Adipose Tissue

(2013) Diane Mathis   Cell Metabolism

T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance

(2013) J. Zhong et al.   DIABETES

CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies

(2012) Dennis Wolf et al.   PLoS One

CD40L Deficiency Ameliorates Adipose Tissue Inflammation and Metabolic Manifestations of Obesity in Mice

(2011) Marjorie Poggi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cutting Edge: CD40-CD40 Ligand Pathway Plays a Critical CD8-Intrinsic and -Extrinsic Role during Rescue of Exhausted CD8 T Cells

(2011) R. Bhadra et al.   JOURNAL OF IMMUNOLOGY

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

(2011) Daniel A Winer et al.   NATURE MEDICINE

Co-stimulatory molecules in and beyond co-stimulation – tipping the balance in atherosclerosis?

(2011) Norbert Gerdes et al.   THROMBOSIS AND HAEMOSTASIS

CD40 Signaling in CD8+CD40+ T Cells Turns On Contra-T Regulatory Cell Functions

(2010) S. Martin et al.   JOURNAL OF IMMUNOLOGY

CD40L induces inflammation and adipogenesis in adipose cells – a potential link between metabolic and cardiovascular disease

(2010) Isabel Platzer et al.   THROMBOSIS AND HAEMOSTASIS

The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes

(2009) M. Poggi et al.   DIABETOLOGIA

Selected Toll-like Receptor Ligands and Viruses Promote Helper-Independent Cytotoxic T Cell Priming by Upregulating CD40L on Dendritic Cells

(2009) Susan Johnson et al.   IMMUNITY

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

(2009) Jian Liu et al.   NATURE MEDICINE

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

The many faces of CD40: Multiple roles in normal immunity and disease

(2009) Dr. Gail A. Bishop   SEMINARS IN IMMUNOLOGY

Foxp3+ regulatory T cells promiscuously accept thymic signals critical for their development

(2008) P. J. Spence et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA