Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches
出版年份 2014 全文链接
标题
Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 15, Issue 6, Pages 10271-10295
出版商
MDPI AG
发表日期
2014-06-10
DOI
10.3390/ijms150610271
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats
- (2014) Marie Stiborová et al. MUTAGENESIS
- The effect of aristolochic acid I on expression of NAD(P)H:quinone oxidoreductase in mice and rats—A comparative study
- (2014) František Bárta et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- The Epidemiology, Diagnosis, and Management of Aristolochic Acid Nephropathy
- (2013) M. Refik Gökmen et al. ANNALS OF INTERNAL MEDICINE
- Enzymes Metabolizing Aristolochic Acid and their Contribution to the Development of Aristolochic Acid Nephropathy and Urothelial Cancer
- (2013) Marie Stiborova et al. CURRENT DRUG METABOLISM
- Exceptionally long-term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy
- (2013) Heinz H. Schmeiser et al. INTERNATIONAL JOURNAL OF CANCER
- Genome-Wide Mutational Signatures of Aristolochic Acid and Its Application as a Screening Tool
- (2013) S. L. Poon et al. Science Translational Medicine
- Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-Exome Sequencing
- (2013) M. L. Hoang et al. Science Translational Medicine
- Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid
- (2013) Marie Stiborová et al. XENOBIOTICA
- Biomonitoring of Aristolactam-DNA Adducts in Human Tissues Using Ultra-Performance Liquid Chromatography/Ion-Trap Mass Spectrometry
- (2012) Byeong Hwa Yun et al. CHEMICAL RESEARCH IN TOXICOLOGY
- The Diesel Exhaust in Miners Study: A Cohort Mortality Study With Emphasis on Lung Cancer
- (2012) Michael D. Attfield et al. JNCI-Journal of the National Cancer Institute
- The Diesel Exhaust in Miners Study: A Nested Case-Control Study of Lung Cancer and Diesel Exhaust
- (2012) D. T. Silverman et al. JNCI-Journal of the National Cancer Institute
- Aristolochic acid-associated urothelial cancer in Taiwan
- (2012) C.-H. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I
- (2012) Katerina Levova et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Role of P450 1A1 and P450 1A2 in Bioactivation versus Detoxication of the Renal Carcinogen Aristolochic Acid I: Studies inCyp1a1(−/−),Cyp1a2(−/−), andCyp1a1/1a2(−/−)Mice
- (2011) Volker M. Arlt et al. CHEMICAL RESEARCH IN TOXICOLOGY
- The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases
- (2011) Marie Stiborová et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- TP53 Mutational signature for aristolochic acid: an environmental carcinogen
- (2011) Masaaki Moriya et al. INTERNATIONAL JOURNAL OF CANCER
- Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid
- (2011) Bojan Jelaković et al. KIDNEY INTERNATIONAL
- Theoretical investigations on the formation of nitrobenzanthrone-DNA Adducts
- (2011) Volker M. Arlt et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model
- (2011) Kateřina Levová et al. TOXICOLOGICAL SCIENCES
- Bioactivation versus Detoxication of the Urothelial Carcinogen Aristolochic Acid I by Human Cytochrome P450 1A1 and 1A2
- (2011) Marie Stiborová et al. TOXICOLOGICAL SCIENCES
- Inhibition of Renal NQO1 Activity by Dicoumarol Suppresses Nitroreduction of Aristolochic Acid I and Attenuates its Nephrotoxicity
- (2011) Min Chen et al. TOXICOLOGICAL SCIENCES
- Mechanisms of the Different DNA Adduct Forming Potentials of the Urban Air Pollutants 2-Nitrobenzanthrone and Carcinogenic 3-Nitrobenzanthrone
- (2010) Marie Stiborová et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Cytochrome P450 1A2 Detoxicates Aristolochic Acid in the Mouse
- (2010) T. A. Rosenquist et al. DRUG METABOLISM AND DISPOSITION
- Gene expression changes induced by the human carcinogen aristolochic acid I in renal and hepatic tissue of mice
- (2010) Volker M. Arlt et al. INTERNATIONAL JOURNAL OF CANCER
- Identification of a Reduction Product of Aristolochic Acid: Implications for the Metabolic Activation of Carcinogenic Aristolochic Acid
- (2010) Horacio A. Priestap et al. JOURNAL OF NATURAL PRODUCTS
- Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats
- (2010) Jana Mizerovská et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Quantification of 3-Nitrobenzanthrone-DNA Adducts Using Online Column-Switching HPLC-Electrospray Tandem Mass Spectrometry
- (2009) Gonçalo Gamboa da Costa et al. CHEMICAL RESEARCH IN TOXICOLOGY
- 3-Aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung
- (2009) Marie Stiborová et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Generation of a ‘humanized’ hCYP1A1_1A2_Cyp1a1/1a2(−/−)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor
- (2008) Zhanquan Shi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mutagenic potential of nitrenium ions of nitrobenzanthrones: Correlation between theory and experiment
- (2008) Jóhannes Reynisson et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Hepatic cytochrome P450s metabolize aristolochic acid and reduce its kidney toxicity
- (2008) Y. Xiao et al. KIDNEY INTERNATIONAL
- Biotransformation enzymes in development of renal injury and urothelial cancer caused by aristolochic acid
- (2008) M. Stiborová et al. KIDNEY INTERNATIONAL
- Aristolochic acid nephropathy: A worldwide problem
- (2008) Frédéric D. Debelle et al. KIDNEY INTERNATIONAL
- The carcinogenic air pollutant 3-nitrobenzanthrone induces GC to TA transversion mutations in human p53 sequences
- (2008) J. vom Brocke et al. MUTAGENESIS
- Genotoxicity of 3-nitrobenzanthrone and 3-aminobenzanthrone in Muta™Mouse and lung epithelial cells derived from Muta™Mouse
- (2008) Volker M. Arlt et al. MUTAGENESIS
- The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity
- (2008) Marie Stiborová et al. TOXICOLOGY
- Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy
- (2007) Marie Stiborová et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
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