Hyperuricaemia: contributions of urate transporter ABCG2 and the fractional renal clearance of urate

Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes

(2015) Hirotaka Matsuo et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update

(2014) Qingcheng Mao et al.   AAPS Journal

Influence of the ABCG2 gout risk 141 K allele on urate metabolism during a fructose challenge

(2014) Nicola Dalbeth et al.   ARTHRITIS RESEARCH & THERAPY

ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload

(2014) Hirotaka Matsuo et al.   Scientific Reports

Sugar-sweetened beverage consumption: a risk factor for prevalent gout withSLC2A9genotype-specific effects on serum urate and risk of gout

(2013) Caitlin Batt et al.   ANNALS OF THE RHEUMATIC DISEASES

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

(2012) Anna Köttgen et al.   NATURE GENETICS

Fractional clearance of urate: validation of measurement in spot-urine samples in healthy subjects and gouty patients

(2012) Diluk RW Kannangara et al.   ARTHRITIS RESEARCH & THERAPY

Decreased extra-renal urate excretion is a common cause of hyperuricemia

(2012) Kimiyoshi Ichida et al.   Nature Communications

A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Māori, case and control sample sets

(2010) Amanda J. Phipps-Green et al.   HUMAN MOLECULAR GENETICS

Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population

(2009) H. Matsuo et al.   Science Translational Medicine

The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane

(2007) M. Huls et al.   KIDNEY INTERNATIONAL