Antiangiogenic ruthenium(ii) benzimidazole complexes, structure-based activation of distinct signaling pathways

A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo

(2014) Taotao Zou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mixed-ligand ruthenium polypyridyl complexes as apoptosis inducers in cancer cells, the cellular translocation and the important role of ROS-mediated signaling

(2014) Zhennan Zhao et al.   DALTON TRANSACTIONS

Synthesis of 2-Pyridyl-benzimidazole Iridium(III), Ruthenium(II), and Platinum(II) Complexes. Study of the Activity as Inhibitors of Amyloid-β Aggregation and Neurotoxicity Evaluation

(2014) Gorakh S. Yellol et al.   INORGANIC CHEMISTRY

Discovery of a Highly Tumor-Selective Organometallic Ruthenium(II)–Arene Complex

(2014) Catherine M. Clavel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ruthenium polypyridyl complexes as inducer of ROS-mediated apoptosis in cancer cells by targeting thioredoxin reductase

(2014) Zuandi Luo et al.   Metallomics

On the antitumor properties of novel cyclometalated benzimidazole Ru(ii), Ir(iii) and Rh(iii) complexes

(2013) Gorakh S. Yellol et al.   CHEMICAL COMMUNICATIONS

Microwave-assisted synthesis of arene ruthenium(II) complexes that induce S-phase arrest in cancer cells by DNA damage-mediated p53 phosphorylation

(2013) Qiong Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Selenocystine potentiates cancer cell apoptosis induced by 5-fluorouracil by triggering reactive oxygen species-mediated DNA damage and inactivation of the ERK pathway

(2013) Cundong Fan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Synthesis, Structural Characterization, and Photophysical, Spectroelectrochemical, and Anion-Sensing Studies of Heteroleptic Ruthenium(II) Complexes Derived from 4′-Polyaromatic-Substituted Terpyridine Derivatives and 2,6-Bis(benzimidazol-2-yl)pyridine

(2013) Dinesh Maity et al.   INORGANIC CHEMISTRY

Interaction between 8-hydroxyquinoline ruthenium(ii) complexes and basic fibroblast growth factors (bFGF): inhibiting angiogenesis and tumor growth through ERK and AKT signaling pathways

(2013) Licong Yang et al.   Metallomics

On the Biological Properties of Alkynyl Phosphine Gold(I) Complexes

(2012) Andreas Meyer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium complexes containing 2,6-bis(benzimidazolyl)pyridine derivatives induce cancer cell apoptosis by triggering DNA damage-mediated p53 phosphorylation

(2012) Linlin Li et al.   DALTON TRANSACTIONS

Molecular and Cellular Characterization of the Biological Effects of Ruthenium(II) Complexes Incorporating 2-Pyridyl-2-pyrimidine-4-carboxylic Acid

(2012) Vanessa Pierroz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhancement of cell permeabilization apoptosis-inducing activity of selenium nanoparticles by ATP surface decoration

(2012) Yibo Zhang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Antiangiogenic and Antimetastatic Activity of JAK Inhibitor AZD1480

(2011) H. Xin et al.   CANCER RESEARCH

Ruthenium complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers

(2011) Linlin Li et al.   DALTON TRANSACTIONS

Synthesis, Structural Characterization, Photophysical, Electrochemical, and Anion-Sensing Studies of Luminescent Homo- and Heteroleptic Ruthenium(II) and Osmium(II) Complexes Based on Terpyridyl-imidazole Ligand

(2011) Chanchal Bhaumik et al.   INORGANIC CHEMISTRY

P-donor ligand containing ruthenium half-sandwich complexes as protein kinase inhibitors

(2011) Craig Streu et al.   INORGANICA CHIMICA ACTA

Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity

(2011) Patrycja Nowak-Sliwinska et al.   JOURNAL OF MEDICINAL CHEMISTRY

Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

(2011) Sònia Tugues et al.   MOLECULAR ASPECTS OF MEDICINE

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Tumor angiogenesis: molecular pathways and therapeutic targets

(2011) Sara M Weis et al.   NATURE MEDICINE

Characterization of a Ruthenium(III)/NAMI-A Adduct with Bovine Serum Albumin that Exhibits a High Anti-Metastatic Activity

(2010) Mimi Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fascinating variability in the chemistry and properties of 2,6-bis-(benzimidazol-2-yl)-pyridine and 2,6-bis-(benzthiazol-2-yl)-pyridine and their complexes

(2010) Miroslav Boča et al.   COORDINATION CHEMISTRY REVIEWS

Synthesis, Characterization, Photophysical, and Anion-Binding Studies of Luminescent Heteroleptic Bis-Tridentate Ruthenium(II) Complexes Based on 2,6-Bis(Benzimidazole-2-yl)Pyridine and 4′-Substituted 2,2′:6′,2′′ Terpyridine Derivatives

(2010) Chanchal Bhaumik et al.   INORGANIC CHEMISTRY

Ruthenium Polypyridyl Complexes That Induce Mitochondria-Mediated Apoptosis in Cancer Cells

(2010) Tianfeng Chen et al.   INORGANIC CHEMISTRY

Modulation of the Biological Properties of Aspirin by Formation of a Bioorganometallic Derivative

(2009) Ingo Ott et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kisspeptin-10, a KISS1-Derived Decapeptide, Inhibits Tumor Angiogenesis by Suppressing Sp1-Mediated VEGF Expression and FAK/Rho GTPase Activation

(2009) S.-G. Cho et al.   CANCER RESEARCH

Morelloflavone, a Biflavonoid, Inhibits Tumor Angiogenesis by Targeting Rho GTPases and Extracellular Signal-Regulated Kinase Signaling Pathways

(2009) X. Pang et al.   CANCER RESEARCH

EPOX Inhibits Angiogenesis by Degradation of Mcl-1 through ERK Inactivation

(2009) H.-L. Sun et al.   CLINICAL CANCER RESEARCH

Naphthalimide gold(i) phosphine complexes as anticancer metallodrugs

(2009) Christoph P. Bagowski et al.   DALTON TRANSACTIONS

A Gold(I) Phosphine Complex Containing a Naphthalimide Ligand Functions as a TrxR Inhibiting Antiproliferative Agent and Angiogenesis Inhibitor

(2009) Ingo Ott et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antiangiogenic strategies for treatment of malignant gliomas

(2009) Andrew S. Chi et al.   Neurotherapeutics

Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy

(2008) Masuko Ushio-Fukai et al.   CANCER LETTERS

Caspase- and p53-dependent apoptosis in breast carcinoma cells induced by a synthetic selenadiazole derivative

(2008) Tianfeng Chen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Tumor Angiogenesis

(2008) Robert S. Kerbel   NEW ENGLAND JOURNAL OF MEDICINE