Relevance of Commensal Microbiota in the Treatment and Prevention of Inflammatory Bowel Disease

Chronically Inflamed Human Tissues Are Infiltrated by Highly Differentiated Th17 Lymphocytes

(2014) J. Pene et al.   JOURNAL OF IMMUNOLOGY

Probiotic-induced apoptosis and its potential relevance to mucosal inflammation of gastrointestinal tract

(2012) U Daniluk et al.   Advances in Medical Sciences

Low prevalence of Helicobacter pylori infection among patients with inflammatory bowel disease

(2012) A. Sonnenberg et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation

(2012) Jasmohan S. Bajaj et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Fecal microbiome transplantation for recurrent Clostridium difficile infection: Report on a case series

(2012) Timothy A. Rubin et al.   ANAEROBE

A potential role of Escherichia coli pathobionts in the pathogenesis of pediatric inflammatory bowel disease

(2012) Serena Schippa et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy

(2012) Omry Koren et al.   CELL

Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota

(2012) Hachung Chung et al.   CELL

Lactocepin Secreted By Lactobacillus Exerts Anti-Inflammatory Effects By Selectively Degrading Proinflammatory Chemokines

(2012) Marie-Anne von Schillde et al.   Cell Host & Microbe

Transient Inability to Manage Proteobacteria Promotes Chronic Gut Inflammation in TLR5-Deficient Mice

(2012) Frederic A. Carvalho et al.   Cell Host & Microbe

Spores from two distinct colony types of the strain Bacillus subtilis PB6 substantiate anti-inflammatory probiotic effects in mice

(2012) Benoît Foligné et al.   CLINICAL NUTRITION

Food and the gut microbiota in inflammatory bowel diseases

(2012) Lindsey G. Albenberg et al.   CURRENT OPINION IN GASTROENTEROLOGY

Probiotics in the Management of Inflammatory Bowel Disease

(2012) Daisy Jonkers et al.   DRUGS

The influence of probiotic supplementation on gut permeability in patients with metabolic syndrome: an open label, randomized pilot study

(2012) B Leber et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Subgingival microflora in inflammatory bowel disease patients with untreated periodontitis

(2012) Fernanda Brito et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Detecting and Treating Clostridium Difficile Infections in Patients with Inflammatory Bowel Disease

(2012) Ashwin N. Ananthakrishnan   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases

(2012) Henri Duboc et al.   GUT

Plasmacytoid Dendritic Cells Transport Peripheral Antigens to the Thymus to Promote Central Tolerance

(2012) Husein Hadeiba et al.   IMMUNITY

Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers

(2012) Megan E. Himmel et al.   IMMUNOLOGY

Enteropathogenic Viruses

(2012) Gwen M.C. Masclee et al.   INFLAMMATORY BOWEL DISEASES

Interactions Between Intestinal Microbiota and Innate Immune System in Pediatric Inflammatory Bowel Disease

(2012) Salvatore Cucchiara et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Nutrigenomics and Nutrigenetics in Inflammatory Bowel Diseases

(2012) Lisa Gruber et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Protective effects of cathelicidin-encoding Lactococcus lactis in murine ulcerative colitis

(2012) Clover Ching Man Wong et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

A Sphingosine-1-Phosphate Receptor 1-Directed Agonist Reduces Central Nervous System Inflammation in a Plasmacytoid Dendritic Cell-Dependent Manner

(2012) G. Galicia-Rosas et al.   JOURNAL OF IMMUNOLOGY

Probiotics to Adolescents With Obesity

(2012) Rikke Juul Gøbel et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Role of nutrition and microbiota in susceptibility to inflammatory bowel diseases

(2012) Liljana Gentschew et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Amelioration of Dextran Sodium Sulfate-Induced Colitis in Mice by Rhodobacter sphaeroides Extract

(2012) Wen-Sheng Liu et al.   MOLECULES

CD8α+β− and CD8α+β+ plasmacytoid dendritic cells induce Foxp3+ regulatory T cells and prevent the induction of airway hyper-reactivity

(2012) V Lombardi et al.   Mucosal Immunology

Gut microbiota composition correlates with diet and health in the elderly

(2012) Marcus J. Claesson et al.   NATURE

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

(2012) Tatsuo Hashimoto et al.   NATURE

Contributions of the microbial hydrogen economy to colonic homeostasis

(2012) Franck Carbonero et al.   Nature Reviews Gastroenterology & Hepatology

The role of the gut microbiota in nutrition and health

(2012) Harry J. Flint et al.   Nature Reviews Gastroenterology & Hepatology

Probiotic Bacteria Produce Conjugated Linoleic Acid Locally in the Gut That Targets Macrophage PPAR γ to Suppress Colitis

(2012) Josep Bassaganya-Riera et al.   PLoS One

Microbiota/Host Crosstalk Biomarkers: Regulatory Response of Human Intestinal Dendritic Cells Exposed to Lactobacillus Extracellular Encrypted Peptide

(2012) David Bernardo et al.   PLoS One

Compartmentalized Control of Skin Immunity by Resident Commensals

(2012) S. Naik et al.   SCIENCE

Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota

(2012) J. C. Arthur et al.   SCIENCE

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Toward an Understanding of Changes in Diversity Associated with Fecal Microbiome Transplantation Based on 16S rRNA Gene Deep Sequencing

(2012) D. Shahinas et al.   mBio

Fecal microbiota transplantation in relapsing Clostridium difficile infection

(2012) Faith Rohlke et al.   Therapeutic Advances in Gastroenterology

Role of the Gut Microbiota in Age-Related Chronic Inflammation

(2012) Tayyab Rehman   Endocrine Metabolic & Immune Disorders-Drug Targets

Randomised clinical trial: the effectiveness of Lactobacillus reuteri ATCC 55730 rectal enema in children with active distal ulcerative colitis

(2011) S. Oliva et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Probiotic Bacteria Induce Maturation of Intestinal Claudin 3 Expression and Barrier Function

(2011) Ravi M. Patel et al.   AMERICAN JOURNAL OF PATHOLOGY

Identification of adeno-associated viral vectors suitable for intestinal gene delivery and modulation of experimental colitis

(2011) Steven Polyak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Generation and Large-Scale Expansion of Human Inducible Regulatory T Cells That Suppress Graft-Versus-Host Disease

(2011) K. L. Hippen et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Differential Targeting of the E-Cadherin/β-Catenin Complex by Gram-Positive Probiotic Lactobacilli Improves Epithelial Barrier Function

(2011) Stephanie Hummel et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Lactobacillus paracaseiReduces Intestinal Inflammation in Adoptive Transfer Mouse Model of Experimental Colitis

(2011) Manuel Oliveira et al.   Clinical & Developmental Immunology

Experimental Inflammatory Bowel Disease: Insights into the Host-Microbiota Dialog

(2011) Maya Saleh et al.   IMMUNITY

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

(2011) Samuel Huber et al.   IMMUNITY

Lactobacillus bulgaricus OLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis

(2011) Takeyuki Takamura et al.   IMMUNOLOGY AND CELL BIOLOGY

Heat-killed body of lactobacillus brevis SBC8803 ameliorates intestinal injury in a murine model of colitis by enhancing the intestinal barrier function

(2011) Nobuhiro Ueno et al.   INFLAMMATORY BOWEL DISEASES

Consumption of probiotics increases the effect of regulatory T cells in transfer colitis

(2011) Emil Rathsach Petersen et al.   INFLAMMATORY BOWEL DISEASES

Buyer beware: Therapeutic claims of probiotics marketed to crohnʼs disease patients via the internet lack supporting data

(2011) Kasra Adham et al.   INFLAMMATORY BOWEL DISEASES

Search with caution: Internet sites target pediatric Crohnʼs patients with probiotics that often claim to be curative

(2011) Kasra Adham et al.   INFLAMMATORY BOWEL DISEASES

How Patients View Probiotics

(2011) MaryBeth Mercer et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Fecal Microbiota Transplantation for Relapsing Clostridium difficile Infection in 26 Patients

(2011) Colleen R. Kelly et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Clostridium difficile infection is associated with worse long term outcome in patients with ulcerative colitis

(2011) Udayakumar Navaneethan et al.   Journal of Crohns & Colitis

Intestinal superinfections in patients with inflammatory bowel diseases

(2011) Elisabetta Antonelli et al.   Journal of Crohns & Colitis

Galactooligosaccharides: Novel Components of Designer Foods

(2011) Vikas Sangwan et al.   JOURNAL OF FOOD SCIENCE

Vitamin A and immune regulation: Role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance

(2011) Barbara Cassani et al.   MOLECULAR ASPECTS OF MEDICINE

Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens

(2011) R. W. DePaolo et al.   NATURE

Fecal microbiota transplantation and emerging applications

(2011) Thomas J. Borody et al.   Nature Reviews Gastroenterology & Hepatology

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lysate of Probiotic Lactobacillus casei DN-114 001 Ameliorates Colitis by Strengthening the Gut Barrier Function and Changing the Gut Microenvironment

(2011) Zuzana Zakostelska et al.   PLoS One

Increase of regulatory T cells in ileal mucosa of untreated pediatric Crohn's disease patients

(2011) Dag Henrik Reikvam et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

(2011) J. L. Round et al.   SCIENCE

Environmental influences on T regulatory cells in inflammatory bowel disease

(2011) Gijs Hardenberg et al.   SEMINARS IN IMMUNOLOGY

Balancing acts: the role of TGF-β in the mucosal immune system

(2011) Joanne E. Konkel et al.   TRENDS IN MOLECULAR MEDICINE

Enterobacteriaceae Act in Concert with the Gut Microbiota to Induce Spontaneous and Maternally Transmitted Colitis

(2010) Wendy S. Garrett et al.   Cell Host & Microbe

Intestinal inflammation abrogates the tolerogenic properties of MLN CD103+ dendritic cells

(2010) Sophie Laffont et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction

(2010) G. Matteoli et al.   GUT

E-Cadherin Marks a Subset of Inflammatory Dendritic Cells that Promote T Cell-Mediated Colitis

(2010) Karima R.R. Siddiqui et al.   IMMUNITY

Immunomodulation by Commensal and Probiotic Bacteria

(2010) Paul Forsythe et al.   IMMUNOLOGICAL INVESTIGATIONS

Orientations of the Bacteroides fragilis Capsular Polysaccharide Biosynthesis Locus Promoters during Symbiosis and Infection

(2010) E. B. Troy et al.   JOURNAL OF BACTERIOLOGY

Use of superoxide dismutase and catalase producing lactic acid bacteria in TNBS induced Crohn's disease in mice

(2010) Jean Guy LeBlanc et al.   JOURNAL OF BIOTECHNOLOGY

MHC class II–restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell–mediated autoimmunity

(2010) Magali Irla et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Central Nervous System Demyelinating Disease Protection by the Human Commensal Bacteroides fragilis Depends on Polysaccharide A Expression

(2010) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease

(2010) J Ochoa-Repáraz et al.   Mucosal Immunology

Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

(2010) Y. K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane sphingolipids as essential molecular signals for Bacteroides survival in the intestine

(2010) D. An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

(2009) S. Brand   GUT

Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease

(2009) Nicola Eastaff-Leung et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning

(2009) I D Iliev et al.   Mucosal Immunology

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Plasmacytoid Dendritic Cells Mediate Oral Tolerance

(2008) Anne Goubier et al.   IMMUNITY

Commensal DNA Limits Regulatory T Cell Conversion and Is a Natural Adjuvant of Intestinal Immune Responses

(2008) Jason A. Hall et al.   IMMUNITY

The probiotic Escherichia coli strain Nissle 1917 induces γδ T cell apoptosis via caspase- and FasL-dependent pathways

(2008) Claudia Guzy et al.   INTERNATIONAL IMMUNOLOGY

Intestinal microflora and immunoregulation

(2008) M Boirivant et al.   Mucosal Immunology

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease

(2008) Husein Hadeiba et al.   NATURE IMMUNOLOGY

Microbial carbohydrate depolymerization by antigen-presenting cells: Deamination prior to presentation by the MHCII pathway

(2008) Jinyou Duan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fecal microflora of Greek healthy neonates

(2007) Evdokia K. Mitsou et al.   ANAEROBE