Insights into B cells and HIV-specific B-cell responses in HIV-infected individuals

CpG Oligonucleotides Enhance Proliferative and Effector Responses of B Cells in HIV-Infected Individuals

(2014) A. Malaspina et al.   JOURNAL OF IMMUNOLOGY

Resting Human Memory B Cells Are Intrinsically Programmed for Enhanced Survival and Responsiveness to Diverse Stimuli Compared to Naive B Cells

(2014) K. L. Good et al.   JOURNAL OF IMMUNOLOGY

B-cell subset alterations and correlated factors in HIV-1 infection

(2013) Simone Pensieroso et al.   AIDS

Broadly Neutralizing Antiviral Antibodies

(2013) Davide Corti et al.   Annual Review of Immunology

Microbial Translocation in the Pathogenesis of HIV Infection and AIDS

(2013) Giulia Marchetti et al.   CLINICAL MICROBIOLOGY REVIEWS

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

(2013) Hua-Xin Liao et al.   IMMUNITY

Atypical and classical memory B cells producePlasmodium falciparumneutralizing antibodies

(2013) Matthias F. Muellenbeck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of Plasmablasts in the Blood of HIV-Infected Viremic Individuals: Evidence for Nonspecific Immune Activation

(2013) C. M. Buckner et al.   JOURNAL OF VIROLOGY

Concerted effect of lymphopenia, viraemia and T-cell activation on Fas expression of peripheral B cells in HIV-1-infected patients

(2012) Bence Rethi et al.   AIDS

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice

(2012) E. M. Hur et al.   BLOOD

A Blueprint for HIV Vaccine Discovery

(2012) Dennis R. Burton et al.   Cell Host & Microbe

Cytokine networks during HIV infection: Shifting the balance

(2012) Elias K. Haddad et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The myeloid cytokine network in AIDS pathogenesis

(2012) Kiran D. Mir et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies

(2012) Peter D. Kwong et al.   IMMUNITY

Human poly- and cross-reactive anti-viral antibodies and their impact on protection and pathology

(2012) Lucile Warter et al.   IMMUNOLOGIC RESEARCH

The establishment of the plasma cell survival niche in the bone marrow

(2012) Van T. Chu et al.   IMMUNOLOGICAL REVIEWS

Interleukin-15 receptor α expression in inflammatory bowel disease patients before and after normalization of inflammation with infliximab

(2012) Clémentine Perrier et al.   IMMUNOLOGY

Expansion of HIV-specific T follicular helper cells in chronic HIV infection

(2012) Madelene Lindqvist et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4 T follicular helper cell dynamics during SIV infection

(2012) Constantinos Petrovas et al.   JOURNAL OF CLINICAL INVESTIGATION

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

(2012) Matthieu Perreau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The origins, function, and regulation of T follicular helper cells

(2012) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spatial Alterations between CD4+ T Follicular Helper, B, and CD8+ T Cells during Simian Immunodeficiency Virus Infection: T/B Cell Homeostasis, Activation, and Potential Mechanism for Viral Escape

(2012) J. J. Hong et al.   JOURNAL OF IMMUNOLOGY

Inhibitory Receptors on Lymphocytes: Insights from Infections

(2012) P. M. Odorizzi et al.   JOURNAL OF IMMUNOLOGY

Chronic Exposure to Plasmodium falciparum Is Associated with Phenotypic Evidence of B and T Cell Exhaustion

(2012) J. Illingworth et al.   JOURNAL OF IMMUNOLOGY

Rapid and Massive Virus-Specific Plasmablast Responses during Acute Dengue Virus Infection in Humans

(2012) J. Wrammert et al.   JOURNAL OF VIROLOGY

B-Lymphocyte Dysfunction in Chronic HIV-1 Infection Does Not Prevent Cross-Clade Neutralization Breadth

(2012) S. Boliar et al.   JOURNAL OF VIROLOGY

Dynamics of Memory B-Cell Populations in Blood, Lymph Nodes, and Bone Marrow during Antiretroviral Therapy and Envelope Boosting in Simian Immunodeficiency Virus SIVmac251-Infected Rhesus Macaques

(2012) T. Demberg et al.   JOURNAL OF VIROLOGY

9G4 Autoreactivity Is Increased in HIV-Infected Patients and Correlates with HIV Broadly Neutralizing Serum Activity

(2012) James J. Kobie et al.   PLoS One

The Impact of B-Cell Perturbations on Pneumococcal Conjugate Vaccine Response in HIV-Infected Adults

(2012) Thomas G. Johannesson et al.   PLoS One

Natural SIV Hosts: Showing AIDS the Door

(2012) Ann Chahroudi et al.   SCIENCE

Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses

(2012) D. R. Burton et al.   SCIENCE

IL-7 in human health and disease

(2012) Wangko Lundström et al.   SEMINARS IN IMMUNOLOGY

HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design

(2012) Mattia Bonsignori et al.   TRENDS IN MICROBIOLOGY

Microbial translocation, immune activation, and HIV disease

(2012) Nichole R. Klatt et al.   TRENDS IN MICROBIOLOGY

Origin and Function of Circulating Plasmablasts during Acute Viral Infections

(2012) Katja Fink   Frontiers in Immunology

How Can HIV-Type-1-Env Immunogenicity Be Improved to Facilitate Antibody-Based Vaccine Development?

(2011) Per Johan Klasse et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Immune Responses to HIV in the Female Reproductive Tract, Immunologic Parallels with the Gastrointestinal Tract, and Research Implications

(2011) Barbara L. Shacklett et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Regulation of mucosal IgA responses: lessons from primary immunodeficiencies

(2011) Andrea Cerutti et al.   Annals of the New York Academy of Sciences

Immunoglobulin Responses at the Mucosal Interface

(2011) Andrea Cerutti et al.   Annual Review of Immunology

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling

(2011) H. W. Sohn et al.   BLOOD

Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

(2011) M. A. Berkowska et al.   BLOOD

Clonal B cells in patients with hepatitis C virus-associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset

(2011) E. D. Charles et al.   BLOOD

Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges

(2011) Morgane Bomsel et al.   IMMUNITY

Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis

(2011) Julien van Grevenynghe et al.   JOURNAL OF CLINICAL INVESTIGATION

Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors

(2011) Lela Kardava et al.   JOURNAL OF CLINICAL INVESTIGATION

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

(2011) Jens Wrammert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells

(2011) Laura M. Fahey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

(2011) Hua-Xin Liao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Prospects for an HIV vaccine: leading B cells down the right path

(2011) Susan Moir et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Acute HIV-1 Infection

(2011) Myron S. Cohen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cross-Sectional Detection of Acute HIV Infection: Timing of Transmission, Inflammation and Antiretroviral Therapy

(2011) Cynthia Gay et al.   PLoS One

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

(2011) X. Wu et al.   SCIENCE

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

(2011) J. F. Scheid et al.   SCIENCE

Innate control of B cell responses

(2011) Andrea Cerutti et al.   TRENDS IN IMMUNOLOGY

The Relationship between CD27 Negative and Positive B Cell Populations in Human Peripheral Blood

(2011) Yu-Chang Bryan Wu et al.   Frontiers in Immunology

The impact of active HIV-1 replication on the physiological age-related decline of immature-transitional B-cells in HIV-1 infected children

(2010) Alberto Cagigi et al.   AIDS

Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression

(2010) Lindi Roberts et al.   AIDS

Effect of highly active antiretroviral therapy on biomarkers of B-lymphocyte activation and inflammation

(2010) Deborah L Regidor et al.   AIDS

High expression levels of B lymphocyte stimulator (BLyS) by dendritic cells correlate with HIV-related B-cell disease progression in humans

(2010) J. Fontaine et al.   BLOOD

B cells in early and chronic HIV infection: evidence for preservation of immune function associated with early initiation of antiretroviral therapy

(2010) S. Moir et al.   BLOOD

Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

(2010) I. Isnardi et al.   BLOOD

Reference values for B cell subpopulations from infancy to adulthood

(2010) H. Morbach et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Human peripheral blood B-cell compartments: A crossroad in B-cell traffic

(2010) M. Perez-Andres et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Optimal Germinal Center Responses Require a Multistage T Cell:B Cell Adhesion Process Involving Integrins, SLAM-Associated Protein, and CD84

(2010) Jennifer L. Cannons et al.   IMMUNITY

Plasma cell development and survival

(2010) Sarah A. Oracki et al.   IMMUNOLOGICAL REVIEWS

Mechanisms that determine plasma cell lifespan and the duration of humoral immunity

(2010) Ian J. Amanna et al.   IMMUNOLOGICAL REVIEWS

Antibody-mediated modulation of immune responses

(2010) Falk Nimmerjahn et al.   IMMUNOLOGICAL REVIEWS

Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses

(2010) J. P. Pereira et al.   INTERNATIONAL IMMUNOLOGY

Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques

(2010) Kehmia Titanji et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapid Generation of Rotavirus-Specific Human Monoclonal Antibodies from Small-Intestinal Mucosa

(2010) R. Di Niro et al.   JOURNAL OF IMMUNOLOGY

Circulating Antibody‐Secreting Cells during Acute Respiratory Syncytial Virus Infection in Adults

(2010) F. Eun‐Hyung Lee et al.   JOURNAL OF INFECTIOUS DISEASES

Dysfunctional B-cell responses during HIV-1 infection: implication for influenza vaccination and highly active antiretroviral therapy

(2010) Alberto Cagigi et al.   LANCET INFECTIOUS DISEASES

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

(2010) X. Wu et al.   SCIENCE

Biomarkers of immune dysfunction in HIV

(2010) Daniel E Nixon et al.   Current Opinion in HIV and AIDS

Immunoregulatory effects of HIV-1 Nef protein

(2009) Maria Giovanna Quaranta et al.   BIOFACTORS

Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells

(2009) S. Suryani et al.   BLOOD

IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection

(2009) I. Sereti et al.   BLOOD

PD-1 and CTLA-4 Inhibitory Cosignaling Pathways in HIV Infection and the Potential for Therapeutic Intervention

(2009) Daniel E. Kaufmann et al.   JOURNAL OF IMMUNOLOGY

Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization

(2009) P. Dosenovic et al.   JOURNAL OF IMMUNOLOGY

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

(2009) A. R. Stacey et al.   JOURNAL OF VIROLOGY

HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4+ cell infection: an IgA gene and functional analysis

(2009) D Tudor et al.   Mucosal Immunology

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

(2009) Johannes F. Scheid et al.   NATURE

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

(2009) Weifeng Xu et al.   NATURE IMMUNOLOGY

Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts

(2009) Donald L Sodora et al.   NATURE MEDICINE

Memory B Cell Function in HIV-Infected Children—Decreased Memory B Cells Despite ART

(2009) Sujal Ghosh et al.   PEDIATRIC RESEARCH

Tissue-Specific B-Cell Dysfunction and Generalized Memory B-Cell Loss during Acute SIV Infection

(2009) Sandrine Peruchon et al.   PLoS One

Timing of HAART defines the integrity of memory B cells and the longevity of humoral responses in HIV-1 vertically-infected children

(2009) S. Pensieroso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Polyclonal B Cell Differentiation and Loss of Gastrointestinal Tract Germinal Centers in the Earliest Stages of HIV-1 Infection

(2009) Marc C. Levesque et al.   PLOS MEDICINE

Evidence for a Pathogenic Determinant in HIV-1 Nef Involved in B Cell Dysfunction in HIV/AIDS

(2008) Simon Swingler et al.   Cell Host & Microbe

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

(2008) Roza I. Nurieva et al.   IMMUNITY

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

(2008) Susan Moir et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A method for identification of HIV gp140 binding memory B cells in human blood

(2008) Johannes F. Scheid et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Normalization of B Cell Counts and Subpopulations after Antiretroviral Therapy in Chronic HIV Disease

(2008) Susan Moir et al.   JOURNAL OF INFECTIOUS DISEASES

Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies

(2008) N. A. Doria-Rose et al.   JOURNAL OF VIROLOGY

Enhancing SIV-specific immunity in vivo by PD-1 blockade

(2008) Vijayakumar Velu et al.   NATURE

Hyperplastic Lymphoid Tissue in HIV/AIDS: An Electron Microscopic Study

(2008) Jan Marc Orenstein   ULTRASTRUCTURAL PATHOLOGY