Activating PIK3CA alleles and lymphangiogenic phenotype of lymphatic endothelial cells isolated from lymphatic malformations

The connection between lymphangiogenic signalling and prostaglandin biology: A missing link in the metastatic pathway

(2015) Tara Karnezis et al.   Oncotarget

Pericytes From Infantile Hemangioma Display Proangiogenic Properties and Dysregulated Angiopoietin-1

(2013) Elisa Boscolo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proteus syndrome review: molecular, clinical, and pathologic features

(2013) M. Michael Cohen   CLINICAL GENETICS

Sturge–Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ

(2013) Matthew D. Shirley et al.   NEW ENGLAND JOURNAL OF MEDICINE

A review of contemporary options for medical management of hemangiomas, other vascular tumors, and vascular malformations

(2013) Julie Blatt et al.   PHARMACOLOGY & THERAPEUTICS

Lymphatic abnormalities are associated with RASA1 gene mutations in mouse and man

(2013) P. E. Burrows et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vascular Anomalies: From Genetics toward Models for Therapeutic Trials

(2013) M. Uebelhoer et al.   Cold Spring Harbor Perspectives in Medicine

The Complex Role of Angiopoietin-2 in the Angiopoietin-Tie Signaling Pathway

(2013) G. Thurston et al.   Cold Spring Harbor Perspectives in Medicine

The New Era of the Lymphatic System: No Longer Secondary to the Blood Vascular System

(2013) I. Choi et al.   Cold Spring Harbor Perspectives in Medicine

Somatic Mosaic Activating Mutations in PIK3CA Cause CLOVES Syndrome

(2012) Kyle C. Kurek et al.   AMERICAN JOURNAL OF HUMAN GENETICS

BMP9 regulates endoglin-dependent chemokine responses in endothelial cells

(2012) K. Young et al.   BLOOD

Oncogenic PI3K Mutations Lead to NF- B-Dependent Cytokine Expression following Growth Factor Deprivation

(2012) J. E. Hutti et al.   CANCER RESEARCH

The CXCL12-CXCR4 Chemokine Pathway: A Novel Axis Regulates Lymphangiogenesis

(2012) W. Zhuo et al.   CLINICAL CANCER RESEARCH

PIK3CA, a hotspot for postzygotic mutations in nonhereditary overgrowth syndromes

(2012) Alireza Baradaran-Heravi   CLINICAL GENETICS

Current Concepts of Vascular Anomalies

(2012) Arin K. Greene   JOURNAL OF CRANIOFACIAL SURGERY

SAR131675, a Potent and Selective VEGFR-3-TK Inhibitor with Antilymphangiogenic, Antitumoral, and Antimetastatic Activities

(2012) A. Alam et al.   MOLECULAR CANCER THERAPEUTICS

Vascular Endothelial Growth Factor Receptor-3 Directly Interacts with Phosphatidylinositol 3-Kinase to Regulate Lymphangiogenesis

(2012) Sanja Coso et al.   PLoS One

Pediatric Vascular Malformations: Pathophysiology, Diagnosis, and the Role of Interventional Radiology

(2011) Anne Marie Cahill et al.   CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY

Mechanoinduction of lymph vessel expansion

(2011) Lara Planas-Paz et al.   EMBO JOURNAL

Lymphatic vascular morphogenesis in development, physiology, and disease

(2011) Stefan Schulte-Merker et al.   JOURNAL OF CELL BIOLOGY

Spectrum of Mutations in Noonan Syndrome and Their Correlation with Phenotypes

(2011) Beom Hee Lee et al.   JOURNAL OF PEDIATRICS

The lymphatic vasculature in disease

(2011) Kari Alitalo   NATURE MEDICINE

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

Akt/Protein Kinase B Is Required for Lymphatic Network Formation, Remodeling, and Valve Development

(2010) Fei Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Lymphatic malformation is a common component of Klippel-Trenaunay syndrome

(2010) Ning-Fei Liu et al.   JOURNAL OF VASCULAR SURGERY

Lymphatic malformations: Current cellular and clinical investigations

(2010) Jonathan A. Perkins et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85α, p55α, and p50α

(2009) Carla Mouta-Bellum et al.   DEVELOPMENTAL DYNAMICS

Molecular Biology and Pathology of Lymphangiogenesis

(2008) Terhi Karpanen et al.   Annual Review of Pathology-Mechanisms of Disease

Multiplexed Assays for Detection of Mutations in PIK3CA

(2008) R. E. Board et al.   CLINICAL CHEMISTRY

The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer†

(2008) Adrian J. Folkes et al.   JOURNAL OF MEDICINAL CHEMISTRY

Many roads lead to oncogene-induced senescence

(2008) S Courtois-Cox et al.   ONCOGENE