标题
Human-induced pluripotent stem cells: potential for neurodegenerative diseases
作者
关键词
-
出版物
HUMAN MOLECULAR GENETICS
Volume 23, Issue R1, Pages R17-R26
出版商
Oxford University Press (OUP)
发表日期
2014-05-14
DOI
10.1093/hmg/ddu204
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease
- (2014) B. Winner et al. HUMAN MOLECULAR GENETICS
- Molecular, genetic and stem cell-mediated therapeutic strategies for spinal muscular atrophy (SMA)
- (2014) Chiara Zanetta et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Stem cell derived basal forebrain cholinergic neurons from Alzheimer’s disease patients are more susceptible to cell death
- (2014) Lishu Duan et al. Molecular Neurodegeneration
- C9orf72 nucleotide repeat structures initiate molecular cascades of disease
- (2014) Aaron R. Haeusler et al. NATURE
- Huntington disease: natural history, biomarkers and prospects for therapeutics
- (2014) Christopher A. Ross et al. Nature Reviews Neurology
- Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
- (2014) Nael H. Alami et al. NEURON
- Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors
- (2014) Andrew A. Sproul et al. PLoS One
- Human stem cell models of neurodegeneration: a novel approach to study mechanisms of disease development
- (2013) Gunnar Hargus et al. ACTA NEUROPATHOLOGICA
- Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
- (2013) Sandra Almeida et al. ACTA NEUROPATHOLOGICA
- A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons
- (2013) Dawei Zhang et al. BIOMATERIALS
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
- (2013) F. Ann Ran et al. CELL
- Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription
- (2013) Scott D. Ryan et al. CELL
- Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production
- (2013) Jered V. McGivern et al. GLIA
- Back to the future: how human induced pluripotent stem cells will transform regenerative medicine
- (2013) C. N. Svendsen HUMAN MOLECULAR GENETICS
- Minimally invasive transplantation of iPSC-derived ALDHhiSSCloVLA4+ neural stem cells effectively improves the phenotype of an amyotrophic lateral sclerosis model
- (2013) Monica Nizzardo et al. HUMAN MOLECULAR GENETICS
- Enhanced Aggregation of Androgen Receptor in Induced Pluripotent Stem Cell-derived Neurons from Spinal and Bulbar Muscular Atrophy
- (2013) Yoshihiro Nihei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of mitochondrial fragmentation diminishes Huntington’s disease–associated neurodegeneration
- (2013) Xing Guo et al. JOURNAL OF CLINICAL INVESTIGATION
- Induced neural stem cells (iNSCs) in neurodegenerative diseases
- (2013) Andreas Hermann et al. JOURNAL OF NEURAL TRANSMISSION
- A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells
- (2013) Matthew F. Burkhardt et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Modeling Huntington's disease with induced pluripotent stem cells
- (2013) Julia A. Kaye et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients
- (2013) O Robicsek et al. MOLECULAR PSYCHIATRY
- Deterministic direct reprogramming of somatic cells to pluripotency
- (2013) Yoach Rais et al. NATURE
- Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells
- (2013) Ryoko Araki et al. NATURE
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
- (2013) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction
- (2013) Laurie H. Sanders et al. NEUROBIOLOGY OF DISEASE
- Remodeling Neurodegeneration: Somatic Cell Reprogramming-Based Models of Adult Neurological Disorders
- (2013) Liang Qiang et al. NEURON
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- Neural Stem Cells: Generating and Regenerating the Brain
- (2013) Fred H. Gage et al. NEURON
- Parkinson's disease in a dish – Using stem cells as a molecular tool
- (2013) J.L. Badger et al. NEUROPHARMACOLOGY
- Neuronal Differentiation and Extensive Migration of Human Neural Precursor Cells following Co-Culture with Rat Auditory Brainstem Slices
- (2013) Ekaterina Novozhilova et al. PLoS One
- Downregulation of MicroRNA-9 in iPSC-Derived Neurons of FTD/ALS Patients with TDP-43 Mutations
- (2013) Zhijun Zhang et al. PLoS One
- Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
- (2013) A. Serio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
- (2013) Z. Hou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification and Rescue of -Synuclein Toxicity in Parkinson Patient-Derived Neurons
- (2013) C. Y. Chung et al. SCIENCE
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
- (2013) D. Sareen et al. Science Translational Medicine
- EZ spheres: A stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs
- (2013) Allison D. Ebert et al. Stem Cell Research
- High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes
- (2013) Jérémie Charbord et al. STEM CELLS
- The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells
- (2013) Grace Woodruff et al. Cell Reports
- Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes
- (2012) The HD iPSC Consortium Cell Stem Cell
- Genetic Correction of Huntington's Disease Phenotypes in Induced Pluripotent Stem Cells
- (2012) Mahru C. An et al. Cell Stem Cell
- Human induced pluripotent stem cells and neurodegenerative disease
- (2012) Yong Wook Jung et al. CURRENT OPINION IN NEUROLOGY
- Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons
- (2012) A. D. Carri et al. DEVELOPMENT
- Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
- (2012) Adriana Sánchez-Danés et al. EMBO Molecular Medicine
- Alzheimer's disease in a dish: promises and challenges of human stem cell models
- (2012) J. E. Young et al. HUMAN MOLECULAR GENETICS
- Generation of Human-Induced Pluripotent Stem Cells to Model Spinocerebellar Ataxia Type 2 In vitro
- (2012) Guangbin Xia et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
- (2012) Mason A. Israel et al. NATURE
- Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression
- (2012) Gabsang Lee et al. NATURE BIOTECHNOLOGY
- The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity
- (2012) Stefano Camnasio et al. NEUROBIOLOGY OF DISEASE
- Establishment of Induced Pluripotent Stem Cells from Centenarians for Neurodegenerative Disease Research
- (2012) Takuya Yagi et al. PLoS One
- Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
- (2012) B. Bilican et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells
- (2012) N. Egawa et al. Science Translational Medicine
- Neuronal Properties, In Vivo Effects, and Pathology of a Huntington's Disease Patient-Derived Induced Pluripotent Stem Cells
- (2012) Iksoo Jeon et al. STEM CELLS
- Generation of Induced Pluripotent Stem Cells from Skin Fibroblasts of a Patient with Olivopontocerebellar Atrophy
- (2012) Yumei Luo et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington’s disease patient cells
- (2012) Tarja A Juopperi et al. Molecular Brain
- Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
- (2012) Yoichi Imaizumi et al. Molecular Brain
- Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
- (2011) Frank Soldner et al. CELL
- LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
- (2011) Ha Nam Nguyen et al. Cell Stem Cell
- Altered Oxygen Metabolism Associated to Neurogenesis of Induced Pluripotent Stem Cells Derived from a Schizophrenic Patient
- (2011) Bruna Da Silveira Paulsen et al. CELL TRANSPLANTATION
- Specification of neuronal and glial subtypes from human pluripotent stem cells
- (2011) Huisheng Liu et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Modeling familial Alzheimer's disease with induced pluripotent stem cells
- (2011) Takuya Yagi et al. HUMAN MOLECULAR GENETICS
- Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients
- (2011) Miguel Mitne-Neto et al. HUMAN MOLECULAR GENETICS
- Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease
- (2011) Yong-Hee Rhee et al. JOURNAL OF CLINICAL INVESTIGATION
- Modelling schizophrenia using human induced pluripotent stem cells
- (2011) Kristen J. Brennand et al. NATURE
- Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease
- (2011) Sonja Kriks et al. NATURE
- Specification of transplantable astroglial subtypes from human pluripotent stem cells
- (2011) Robert Krencik et al. NATURE BIOTECHNOLOGY
- SNCA Triplication Parkinson's Patient's iPSC-derived DA Neurons Accumulate α-Synuclein and Are Susceptible to Oxidative Stress
- (2011) Blake Byers et al. PLoS One
- Brief Report: Phenotypic Rescue of Induced Pluripotent Stem Cell-Derived Motoneurons of a Spinal Muscular Atrophy Patient
- (2011) Tammy Chang et al. STEM CELLS
- Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
- (2010) Luigi Warren et al. Cell Stem Cell
- Huntington's disease: from molecular pathogenesis to clinical treatment
- (2010) Christopher A Ross et al. LANCET NEUROLOGY
- Specification of Region-Specific Neurons Including Forebrain Glutamatergic Neurons from Human Induced Pluripotent Stem Cells
- (2010) Hui Zeng et al. PLoS One
- Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats
- (2010) G. Hargus et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Humanized Mice for Modeling Human Infectious Disease: Challenges, Progress, and Outlook
- (2009) Nicolas Legrand et al. Cell Host & Microbe
- Gene Targeting of a Disease-Related Gene in Human Induced Pluripotent Stem and Embryonic Stem Cells
- (2009) Jizhong Zou et al. Cell Stem Cell
- Adult mice generated from induced pluripotent stem cells
- (2009) Michael J. Boland et al. NATURE
- iPS cells produce viable mice through tetraploid complementation
- (2009) Xiao-yang Zhao et al. NATURE
- Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
- (2009) Stuart M Chambers et al. NATURE BIOTECHNOLOGY
- Differentiation of human oligodendrocytes from pluripotent stem cells
- (2009) Bao-Yang Hu et al. Nature Protocols
- Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
- (2009) Noemi FUSAKI et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
- (2009) J. Yu et al. SCIENCE
- Disease-Specific Induced Pluripotent Stem Cells
- (2008) In-Hyun Park et al. CELL
- Induced pluripotent stem cells from a spinal muscular atrophy patient
- (2008) Allison D. Ebert et al. NATURE
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
- Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats
- (2008) L. Aubry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
- (2008) M. Wernig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induced Pluripotent Stem Cells Generated Without Viral Integration
- (2008) M. Stadtfeld et al. SCIENCE
- Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
- (2008) J. T. Dimos et al. SCIENCE
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