Birt–Hogg–Dubé syndrome is a novel ciliopathy

2-APB-potentiated channels amplify CatSper-induced Ca2+signals in human sperm

(2012) Linda Lefièvre et al.   BIOCHEMICAL JOURNAL

The Birt-Hogg-Dube tumor suppressor Folliculin negatively regulates ribosomal RNA synthesis

(2012) K. Gaur et al.   HUMAN MOLECULAR GENETICS

Coevolution Reveals a Network of Human Proteins Originating with Multicellularity

(2012) A. Bezginov et al.   MOLECULAR BIOLOGY AND EVOLUTION

The LKB1 Tumor Suppressor Controls Spindle Orientation and Localization of Activated AMPK in Mitotic Epithelial Cells

(2012) Chongjuan Wei et al.   PLoS One

Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer

(2012) R. K. Nookala et al.   Open Biology

Ultrastructure of cilia and flagella - back to the future!

(2011) Cathy Fisch et al.   BIOLOGY OF THE CELL

Renal cancer and pneumothorax risk in Birt–Hogg–Dubé syndrome; an analysis of 115 FLCN mutation carriers from 35 BHD families

(2011) A C Houweling et al.   BRITISH JOURNAL OF CANCER

Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

(2011) Liyun Sang et al.   CELL

Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia

(2011) J. B. Wallingford et al.   GENES & DEVELOPMENT

The cilia protein IFT88 is required for spindle orientation in mitosis

(2011) Benedicte Delaval et al.   NATURE CELL BIOLOGY

Subcellular spatial regulation of canonical Wnt signalling at the primary cilium

(2011) Madeline A. Lancaster et al.   NATURE CELL BIOLOGY

Ciliogenesis: building the cell's antenna

(2011) Hiroaki Ishikawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ciliopathies

(2011) Friedhelm Hildebrandt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss of the Birt–Hogg–Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription

(2011) T P Cash et al.   ONCOGENE

Primary Cilium Depletion Typifies Cutaneous Melanoma In Situ and Malignant Melanoma

(2011) Jinah Kim et al.   PLoS One

VHL-gene Deletion in Single Renal Tubular Epithelial Cells and Renal Tubular Cysts: Further Evidence for a Cyst-dependent Progression Pathway of Clear Cell Renal Carcinoma in von Hippel-Lindau Disease

(2010) Matteo Montani et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

A role for central spindle proteins in cilia structure and function

(2010) Katherine R. Smith et al.   Cytoskeleton

Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability

(2010) Claudio R. Thoma et al.   JOURNAL OF CELL BIOLOGY

Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-β signaling

(2010) Seung-Beom Hong et al.   Molecular Cancer

Absence of the Birt–Hogg–Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

(2010) R S Preston et al.   ONCOGENE

Inactivation of the FLCN Tumor Suppressor Gene Induces TFE3 Transcriptional Activity by Increasing Its Nuclear Localization

(2010) Seung-Beom Hong et al.   PLoS One

Cystic kidney disease: the role of Wnt signaling

(2010) Madeline A. Lancaster et al.   TRENDS IN MOLECULAR MEDICINE

The motile cilium in development and disease: emerging new insights

(2009) Sudipto Roy   BIOESSAYS

Birt-Hogg-Dubé syndrome: clinical and genetic studies of 10 French families

(2009) N. Kluger et al.   BRITISH JOURNAL OF DERMATOLOGY

Blockade of Wnt Signaling Inhibits Angiogenesis and Tumor Growth in Hepatocellular Carcinoma

(2009) J. Hu et al.   CANCER RESEARCH

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Rab35 - A vesicular traffic-regulating small GTPase with actin modulating roles

(2009) Christelle En Lin Chua et al.   FEBS LETTERS

Renal tumour suppressor function of the Birt-Hogg-Dube syndrome gene product folliculin

(2009) V. Hudon et al.   JOURNAL OF MEDICAL GENETICS

Planar Cell Polarity and the Kidney

(2009) H. McNeill   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Birt-Hogg-Dubé syndrome: diagnosis and management

(2009) Fred H Menko et al.   LANCET ONCOLOGY

The role of the Birt–Hogg–Dubé protein in mTOR activation and renal tumorigenesis

(2009) T R Hartman et al.   ONCOGENE

Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2

(2009) Y. Hasumi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Planar cell polarity and cilia

(2009) Evelyne Fischer et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The UOK 257 cell line: a novel model for studies of the human Birt–Hogg–Dubé gene pathway

(2008) Youfeng Yang et al.   CANCER GENETICS AND CYTOGENETICS

Cell Cycle-Dependent Ciliogenesis and Cancer

(2008) O. V. Plotnikova et al.   CANCER RESEARCH

Familial Non-VHL Clear Cell (Conventional) Renal Cell Carcinoma: Clinical Features, Segregation Analysis, and Mutation Analysis of FLCN

(2008) E. R. Woodward et al.   CLINICAL CANCER RESEARCH

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia

(2008) Vishal Patel et al.   HUMAN MOLECULAR GENETICS

The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway

(2008) Tiffiney R. Hartman et al.   HUMAN MOLECULAR GENETICS

Kidney-Targeted Birt-Hogg-Dube Gene Inactivation in a Mouse Model: Erk1/2 and Akt-mTOR Activation, Cell Hyperproliferation, and Polycystic Kidneys

(2008) M. Baba et al.   JNCI-Journal of the National Cancer Institute

Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein

(2008) Y Takagi et al.   ONCOGENE