期刊
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
卷 20, 期 8, 页码 998-1005出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcdb.2009.09.016
关键词
Oriented cell division; Planar cell polarity; Cilium; Ciliopathies
In the last few years, evidence has come to light suggesting that planar cell polarity signaling in vertebrates may be controlled and modulated by primary cilia, subcellular organelles that emerge from the plasma membrane of most cell types. This characteristic distinguishes vertebrate planar cell polarity signaling from that in insects. We review here some of the experimental evidence contributing to this finding. These observations have begun to suggest molecular and cellular mechanisms of the so-called ciliopathies, important human diseases characterized by defective ciliary functions. (C) 2009 Published by Elsevier Ltd.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据