Loss of the Birt–Hogg–Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription

Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-β signaling

(2010) Seung-Beom Hong et al.   Molecular Cancer

Ars2 Links the Nuclear Cap-Binding Complex to RNA Interference and Cell Proliferation

(2009) Joshua J. Gruber et al.   CELL

Essential and overlapping functions for mammalian Argonautes in microRNA silencing

(2009) H. Su et al.   GENES & DEVELOPMENT

Transforming Growth Factor-β1 (TGF-β1) Induces Human Osteoclast Apoptosis by Up-regulating Bim

(2009) Nicolas Houde et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Renal tumour suppressor function of the Birt-Hogg-Dube syndrome gene product folliculin

(2009) V. Hudon et al.   JOURNAL OF MEDICAL GENETICS

CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma

(2009) Fiona E McRonald et al.   Molecular Cancer

βTrCP- and Rsk1/2-Mediated Degradation of BimEL Inhibits Apoptosis

(2009) Elinor Dehan et al.   MOLECULAR CELL

The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIMEL

(2009) Y Guo et al.   ONCOGENE

The role of the Birt–Hogg–Dubé protein in mTOR activation and renal tumorigenesis

(2009) T R Hartman et al.   ONCOGENE

Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2

(2009) Y. Hasumi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGFβ in Cancer

(2008) Joan Massagué   CELL

Familial Non-VHL Clear Cell (Conventional) Renal Cell Carcinoma: Clinical Features, Segregation Analysis, and Mutation Analysis of FLCN

(2008) E. R. Woodward et al.   CLINICAL CANCER RESEARCH

TGFβ-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2

(2008) Sneha Ramesh et al.   EMBO REPORTS

Kidney-Targeted Birt-Hogg-Dube Gene Inactivation in a Mouse Model: Erk1/2 and Akt-mTOR Activation, Cell Hyperproliferation, and Polycystic Kidneys

(2008) M. Baba et al.   JNCI-Journal of the National Cancer Institute

Identification of the gene transcription and apoptosis mediated by TGF-β-Smad2/3-Smad4 signaling

(2007) Jian Yu et al.   JOURNAL OF CELLULAR PHYSIOLOGY