Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics

Genetic Therapeutic Approaches for Duchenne Muscular Dystrophy

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TLR2 and TLR4 Activate p38 MAPK and JNK during Endurance Exercise in Skeletal Muscle

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Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

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The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.

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Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle

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PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis

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Plasmid DNA Gene Therapy by Electroporation: Principles and Recent Advances

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Impending therapies for Duchenne muscular dystrophy

(2011) Terence A. Partridge   CURRENT OPINION IN NEUROLOGY

Progress in therapy for Duchenne muscular dystrophy

(2011) Rebecca J. Fairclough et al.   EXPERIMENTAL PHYSIOLOGY

Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice

(2011) M. H. Kim et al.   HUMAN MOLECULAR GENETICS

Therapeutic approaches to muscular dystrophy

(2011) A. Goyenvalle et al.   HUMAN MOLECULAR GENETICS

Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle

(2011) V. Ljubicic et al.   HUMAN MOLECULAR GENETICS

Tristetraprolin Regulates Interleukin-6 Expression Through p38 MAPK-Dependent Affinity Changes with mRNA 3′ Untranslated Region

(2011) Wenpu Zhao et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Chaperone Hsp27 Modulates AUF1 Proteolysis and AU-Rich Element-Mediated mRNA Degradation

(2011) A. M. Knapinska et al.   MOLECULAR AND CELLULAR BIOLOGY

Posttranscriptional Control of Type I Interferon Genes by KSRP in the Innate Immune Response against Viral Infection

(2011) W.-J. Lin et al.   MOLECULAR AND CELLULAR BIOLOGY

Daily Treatment with SMTC1100, a Novel Small Molecule Utrophin Upregulator, Dramatically Reduces the Dystrophic Symptoms in the mdx Mouse

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Translational Regulation of Utrophin by miRNAs

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RNA-binding proteins and gene regulation in myogenesis

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Mechanisms and functions of p38 MAPK signalling

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Dystrophin: More than just the sum of its parts

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TNF/p38α/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration

(2010) Daniela Palacios et al.   Cell Stem Cell

The utrophin A 5'-UTR drives cap-independent translation exclusively in skeletal muscles of transgenic mice and interacts with eEF1A2

(2010) P. Miura et al.   HUMAN MOLECULAR GENETICS

CT-GalNAc transferase overexpression in adult mice is associated with extrasynaptic utrophin in skeletal muscle fibres

(2010) Margaret Durko et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets

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Cooperation between myogenic regulatory factors and SIX family transcription factors is important for myoblast differentiation

(2010) Yubing Liu et al.   NUCLEIC ACIDS RESEARCH

AREsite: a database for the comprehensive investigation of AU-rich elements

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The p38 MAPK Regulates IL-24 Expression by Stabilization of the 3′ UTR of IL-24 mRNA

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Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice

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Differential Expression of Utrophin-A and -B Promoters in the Central Nervous System (CNS) of Normal and DystrophicmdxMice

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Pharmacological activation of PPAR /  stimulates utrophin A expression in skeletal muscle fibers and restores sarcolemmal integrity in mature mdx mice

(2009) P. Miura et al.   HUMAN MOLECULAR GENETICS

The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism

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The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

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Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding

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Down-Regulation of Akt/Mammalian Target of Rapamycin Signaling Pathway in Response to Myostatin Overexpression in Skeletal Muscle

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The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels

(2008) Morris Nechama et al.   FASEB JOURNAL

Myogenic Akt signaling upregulates the utrophin–glycoprotein complex and promotes sarcolemma stability in muscular dystrophy

(2008) Angela K. Peter et al.   HUMAN MOLECULAR GENETICS

Decoding ARE-mediated decay: is microRNA part of the equation?

(2008) Christopher von Roretz et al.   JOURNAL OF CELL BIOLOGY

IRES-Mediated Translation of Utrophin A Is Enhanced by Glucocorticoid Treatment in Skeletal Muscle Cells

(2008) Pedro Miura et al.   PLoS One