Stem cell derived in vivo-like human cardiac bodies in a microfluidic device for toxicity testing by beating frequency imaging

Identification of novel biomarkers for doxorubicin-induced toxicity in human cardiomyocytes derived from pluripotent stem cells

(2015) Gustav Holmgren et al.   TOXICOLOGY

A microfluidic-based platform for tumour spheroid culture, monitoring and drug screening

(2014) K. Kwapiszewska et al.   LAB ON A CHIP

Macroporous microcarriers for introducing cells into a microfluidic chip

(2014) G. Bergström et al.   LAB ON A CHIP

On-chip in vitro cell-network pre-clinical cardiac toxicity using spatiotemporal human cardiomyocyte measurement on a chip

(2014) Tomoyuki Kaneko et al.   Scientific Reports

Controlling Expansion and Cardiomyogenic Differentiation of Human Pluripotent Stem Cells in Scalable Suspension Culture

(2014) Henning Kempf et al.   Stem Cell Reports

Highly Elastic Micropatterned Hydrogel for Engineering Functional Cardiac Tissue

(2013) Nasim Annabi et al.   ADVANCED FUNCTIONAL MATERIALS

The use of agarose microwells for scalable embryoid body formation and cardiac differentiation of human and murine pluripotent stem cells

(2013) Julia Dahlmann et al.   BIOMATERIALS

Novel in vitro cardiovascular constructs composed of vascular-like networks and cardiomyocytes

(2013) Hanna Vuorenpää et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Microfluidic heart on a chip for higher throughput pharmacological studies

(2013) Ashutosh Agarwal et al.   LAB ON A CHIP

Engineering of functional, perfusable 3D microvascular networks on a chip

(2013) Sudong Kim et al.   LAB ON A CHIP

A Novel 3D Label-Free Monitoring System of hES-Derived Cardiomyocyte Clusters: A Step Forward to In Vitro Cardiotoxicity Testing

(2013) Heinz-Georg Jahnke et al.   PLoS One

Comparison of Electrophysiological Data From Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes to Functional Preclinical Safety Assays

(2013) Kate Harris et al.   TOXICOLOGICAL SCIENCES

Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity

(2013) Oksana Sirenko et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A high content screening assay to predict human drug-induced liver injury during drug discovery

(2013) Mikael Persson et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Murine and human pluripotent stem cell-derived cardiac bodies form contractile myocardial tissue in vitro

(2012) George Kensah et al.   EUROPEAN HEART JOURNAL

Development of High Content Imaging Methods for Cell Death Detection in Human Pluripotent Stem Cell-Derived Cardiomyocytes

(2012) Maxime Mioulane et al.   Journal of Cardiovascular Translational Research

Impedance-Based Detection of Beating Rhythm and Proarrhythmic Effects of Compounds on Stem Cell-Derived Cardiomyocytes

(2011) Malin K.B. Jonsson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review

(2011) Carl-Fredrik Mandenius et al.   JOURNAL OF APPLIED TOXICOLOGY

Scalable expansion of human pluripotent stem cells in suspension culture

(2011) Robert Zweigerdt et al.   Nature Protocols

Noninvasive Evaluation of Contractile Behavior of Cardiomyocyte Monolayers Based on Motion Vector Analysis

(2011) Tomohiro Hayakawa et al.   TISSUE ENGINEERING PART C-METHODS

Non-invasive characterization of mouse embryonic stem cell derived cardiomyocytes based on the intensity variation in digital beating video

(2010) Mohammad Mosharraf Hossain et al.   ANALYST

Monitoring of troponin release from cardiomyocytes during exposure to toxic substances using surface plasmon resonance biosensing

(2010) Henrik Andersson et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Assaying cardiac biomarkers for toxicity testing using biosensing and cardiomyocytes derived from human embryonic stem cells

(2010) Henrik Andersson et al.   JOURNAL OF BIOTECHNOLOGY

Report and Recommendations of the Workshop of the European Centre for the Validation of Alternative Methods for Drug-Induced Cardiotoxicity

(2009) Tina C. Stummann et al.   Cardiovascular Toxicology

A microfluidic 3D hepatocyte chip for drug toxicity testing

(2009) Yi-Chin Toh et al.   LAB ON A CHIP

Robotic multiwell planar patch-clamp for native and primary mammalian cells

(2009) Carol J Milligan et al.   Nature Protocols

Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs

(2009) D.-H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues

(2009) W. R. Legant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA