Čedomir Stevčić

Serbia n/a

论文

评论了 Using the Avocado to Test the Satiety Effects of a Fat-Fiber Combination in Place of Carbohydrate Energy in a Breakfast Meal in Overweight and Obese Men and Women: A Randomized Clinical Trial
This study shows that overweight or obese volunteers who had eaten avocado as part of a meal felt less hungry after 6 hours, compared with those who had eaten a low-fat, high-carbohydrate meal because avocado contains a rare combination of healthful fats and fiber and is associated with many health benefits.

论文

评论了 Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice
The authors discovered that the bacterial species *Clostridioides difficile*, which is known for causing serious diarrheal infections, is responsible for certain colorectal cancers.

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评论了 Effect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial
This is the largest and longest avocado research study (more than 1,000 participants) which is conducted by 5 universities, and it showed that eating one avocado every day for six months had no impact on waist circumference, belly fat, or liver fat in those who were overweight or obese, but it decreased their unhealthy cholesterol levels.

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评论了 Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer
The authors defined how the circadian clock influences cell growth, metabolism, and tumor progression - they demonstrated that both genetic and environmental disruption of the circadian clock can drive colorectal cancer progression.

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评论了 Comparative transcriptional analyses in the nucleus accumbens identifies RGS2 as a key mediator of depression-related behavior
The authors identified a possible explanation why women may not react to treatments for depression similarly to men as women usually have greater rates of depression than males - depression symptoms may have been triggered by alterations of the nucleus accumbens (i.e. specific genes were switched on or off in women with depression but not in males) or the depressive episode itself may have altered the brain.

论文

评论了 Fish intake and risk of melanoma in the NIH-AARP diet and health study
This large study of US adults (491,367 participants, 62 years old on average) showed that high fish consumption (including tuna and non-fried fish) is related to an increased risk of cancer (i.e. malignant melanoma) - its incidence was 22% greater among individuals whose median daily consumption of fish was 42.8 grams as compared to those whose median daily intake was 3.2 grams.

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评论了 Sex Differences in the Alcohol-Mediated Modulation of BLA Network States
The authors discovered that alcohol changes the synchronized brain activity in the amygdala of mice, but alcohol alters amygdala activity differently in male and female mice, which suggests that alcohol can trigger the amygdala to switch activity states and drive changes in anxious and fearful behavior.

论文

评论了 Nonalcoholic Fatty Liver Disease and Risk of Dementia
The authors investigated 2,898 people (65 years old and older) over 30 years and discovered that people who have a non-alcoholic fatty liver disease (i.e. an accumulation of fat cells in the liver) could have a 38% higher risk of dementia.

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评论了 TDP ‐43 Proteinopathy Presenting with Typical Symptoms of Parkinson's Disease
The authors found an unexpected alteration in the brain (an accumulation of TDP-43 proteins rather than alpha-synuclein) during the autopsy of a patient with clinically typical Parkinson’s disease, which shows that a buildup of Lewy bodies is not the only way that Parkinson’s disease-related cell death can happen.

论文

评论了 Phage Therapy of Mycobacterium Infections: Compassionate-use of Phages in Twenty Patients with Drug-Resistant Mycobacterial Disease
The authors successfully used bacteria-eating viruses to treat 20 complex and antibiotic-resistant lung infections without side effects, and more than half of the patients had favorable clinical results.

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评论了 Disordered, Sub-Nanometer Ru Structures on CeO2 are Highly Efficient and Selective Catalysts in Polymer Upcycling by Hydrogenolysis
The authors developed a plastics recycling innovation that more efficiently converts plastics to valuable commodity chemicals, produces much less methane, and simultaneously increases conversion to useful products while using less of the precious metal ruthenium, which makes the catalyst much cheaper.

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评论了 Genetic and structural basis of the human anti-α-galactosyl antibody response
The authors revealed the genetic and molecular structure of certain key molecules connected to the potentially fatal mammalian-meat allergy caused by tick bites, which opens the door to potential future treatments: description of how antibodies interact with the sugar molecule galactose-α-1,3-galactose and that α-gal serves as the key molecule for this particular allergy.

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评论了 Effect of Yoga in the Therapy of Irritable Bowel Syndrome: A Systematic Review
This review included six randomized controlled trials (a total of 273 people) and it concluded that yoga can be a supportive and safe treatment for people with irritable bowel syndrome (IBS).

论文

评论了 Impact of psychological stress on irritable bowel syndrome
The author found that psychological stress can have a substantial impact on the motility, permeability, secretion, and overall sensitivity of the intestinal tract.

论文

评论了 Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study
This is the world-first genetic study that shows a direct connection between high levels of inflammation and low levels of vitamin D by examining the genetic data of 294,970 participants in the UK. Hence, the study provides an important biomarker to identify people at higher risk of chronic inflammatory illnesses (e.g. type 2 diabetes, heart disease, and autoimmune diseases).