Evaluation of Health-Related Quality of Life (HRQoL) in Patients Receiving Outpatient Parenteral Antimicrobial Therapy (OPAT)

Authors

Oyewole Chris Durojaiye¹ , Sue Fearn¹ , Ellie Birnie¹ , Hannah Whitlock¹ , Thomas New¹ , Palvinder Chohan¹

1. Dept of Microbiology, Royal Derby Hospital, Derby (UK)

Conference / event

NATIONAL OPAT CONFERENCE 2023, November 2023 (OYAL COLLEGE OF PHYSICIANS, LONDON & ONLINE, United Kingdom)

Poster summary

We conducted a prospective cohort study involving all adult patients who received OPAT at the University Hospitals of Derby and Burton (UHDB) NHS Foundation Trust in Derbyshire, England (UK) between October 2022 and September 2023. The participants' HRQoL was assessed using the EQ-5D-3L questionnaire. The mean EQ-5D VAS (58.45 vs. 82.48) and index value (0.51 vs. 0.86) scores at baseline were significantly lower than the UK population average (p < 0.001). The median increase in the health state index score was 0.13 (Z=5.64; p<0.001), while the median gain in VAS score was 10 (Z = 3.62; p<0.001). There were significant increases in the proportion of patients who had no problems walking about (10.7%; p=0.003); no problems with self-care (13.3%; p=0.002); no problems performing daily activities (18.0%; p<0.001); and no pain/discomfort (18.0%; p<0.001). OPAT is associated with improved patient-reported quality of life measures and allows early return to work or school.

Keywords

Benefits, EQ-5D-3L, OPAT, Outpatient parenteral antimicrobial therapy, Quality of life

Research areas

Medicine, Microbiology

References

No data provided

Funding

No data provided

Supplemental files

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Additional information

Competing interests

No competing interests were disclosed.

Data availability statement

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

Creative Commons license

Copyright © 2023 Durojaiye et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.