FGF/FGFR signaling in bone formation: Progress and perspectives

Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling

(2011) Aline Martin et al.   FASEB JOURNAL

Fibroblast Growth Factor 2 Stimulation of Osteoblast Differentiation and Bone Formation Is Mediated by Modulation of the Wnt Signaling Pathway

(2011) Yurong Fei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Casitas B Lineage Lymphoma (Cbl) Mutant G306E Enhances Osteogenic Differentiation in Human Mesenchymal Stromal Cells in Part by Decreased Cbl-mediated Platelet-derived Growth Factor Receptor α and Fibroblast Growth Factor Receptor 2 Ubiquitination

(2011) Nicolas Sévère et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone

(2011) Simon Wöhrle et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Functional characterization of a novel FGFR2 mutation, E731K, in craniosynostosis

(2011) Jounghyen Park et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Fgf-18 Is Required for Osteogenesis But Not Angiogenesis During Long Bone Repair

(2011) Björn Behr et al.   TISSUE ENGINEERING PART A

Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells

(2010) Liping Xiao et al.   BONE

The transcription factor Sox2 is required for osteoblast self-renewal

(2010) U Basu-Roy et al.   CELL DEATH AND DIFFERENTIATION

Pivotal role of Twist in skeletal biology and pathology

(2010) Hichem Miraoui et al.   GENE

Increased EFG- and PDGF -receptor signaling by mutant FGF-receptor 2 contributes to osteoblast dysfunction in Apert craniosynostosis

(2010) H. Miraoui et al.   HUMAN MOLECULAR GENETICS

Gain-of-function mutation in FGFR3 in mice leads to decreased bone mass by affecting both osteoblastogenesis and osteoclastogenesis

(2010) N. Su et al.   HUMAN MOLECULAR GENETICS

Molecular silencing of Twist1 enhances osteogenic differentiation of murine mesenchymal stem cells: Implication of FGFR2 signaling

(2010) Hichem Miraoui et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Autocrine fibroblast growth factor 18 mediates dexamethasone-induced osteogenic differentiation of murine mesenchymal stem cells

(2010) Zahia Hamidouche et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Fibroblast Growth Factor Receptor Signaling Crosstalk in Skeletogenesis

(2010) H. Miraoui et al.   Science Signaling

Fibroblast Growth Factor Receptor 2 Promotes Osteogenic Differentiation in Mesenchymal Cells via ERK1/2 and Protein Kinase C Signaling

(2009) Hichem Miraoui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts

(2009) Nadiya M. Teplyuk et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Novel Regulators of Fgf23 Expression and Mineralization in Hyp Bone

(2009) Shiguang Liu et al.   MOLECULAR ENDOCRINOLOGY

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

FGFR2-Cbl interaction in lipid rafts triggers attenuation of PI3K/Akt signaling and osteoblast survival

(2008) Cécilie Dufour et al.   BONE

Twist1 homodimers enhance FGF responsiveness of the cranial sutures and promote suture closure

(2008) Jeannette Connerney et al.   DEVELOPMENTAL BIOLOGY

Exported 18-kDa Isoform of Fibroblast Growth Factor-2 Is a Critical Determinant of Bone Mass in Mice

(2008) Liping Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous FGF-2 is critically important in PTH anabolic effects on bone

(2008) Maria Giovanna Sabbieti et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sustained Platelet-Derived Growth Factor Receptor   Signaling in Osteoblasts Results in Craniosynostosis by Overactivating the Phospholipase C-  Pathway

(2008) A. Moenning et al.   MOLECULAR AND CELLULAR BIOLOGY

Fibroblast Growth Factor Signaling Uses Multiple Mechanisms To Inhibit Wnt-Induced Transcription in Osteoblasts

(2008) D. Ambrosetti et al.   MOLECULAR AND CELLULAR BIOLOGY

Fibroblast Growth Factor-2 and -4 Promote the Proliferation of Bone Marrow Mesenchymal Stem Cells by the Activation of the PI3K-Akt and ERK1/2 Signaling Pathways

(2008) Seung-Cheol Choi et al.   STEM CELLS AND DEVELOPMENT

FGF signaling: its role in bone development and human skeleton diseases

(2007) Nan Su   Frontiers in Bioscience-Landmark

Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways

(2007) Angela Raucci et al.   JOURNAL OF CELLULAR PHYSIOLOGY