Microglial activation of the NLRP3 inflammasome by the priming signals derived from macrophages infected with mycobacteria

Temporal Changes in Cell Marker Expression and Cellular Infiltration in a Controlled Cortical Impact Model in Adult Male C57BL/6 Mice

(2012) Xuemei Jin et al.   PLoS One

Mitochondria: Sovereign of inflammation?

(2011) Jürg Tschopp   EUROPEAN JOURNAL OF IMMUNOLOGY

Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-1-Syk and p62/SQSTM1

(2011) Hye-Mi Lee et al.   IMMUNOLOGY AND CELL BIOLOGY

Inflammasome-Independent Modulation of Cytokine Response by Autophagy in Human Cells

(2011) Tania O. Crişan et al.   PLoS One

Disease-associated amyloid and misfolded protein aggregates activate the inflammasome

(2011) Seth L. Masters et al.   TRENDS IN MOLECULAR MEDICINE

Dexamethasone prevents LPS-induced microglial activation and astroglial impairment in an experimental bacterial meningitis co-culture model

(2010) Daniel Hinkerohe et al.   BRAIN RESEARCH

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

(2010) Bibhuti B. Mishra et al.   CELLULAR MICROBIOLOGY

Critical functions of priming and lysosomal damage for NLRP3 activation

(2010) Veit Hornung et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-27 inhibits OSM-mediated TNF-α and iNOS gene expression in microglia

(2010) Brandi J. Baker et al.   GLIA

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

(2010) C. Bauer et al.   GUT

NALP3 is not necessary for early protection against experimental tuberculosis

(2010) Kerstin Walter et al.   IMMUNOBIOLOGY

Autophagy Negatively Regulates Keratinocyte Inflammatory Responses via Scaffolding Protein p62/SQSTM1

(2010) H.-M. Lee et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis Upregulates Microglial Matrix Metalloproteinase-1 and -3 Expression and Secretion via NF- B- and Activator Protein-1-Dependent Monocyte Networks

(2010) J. A. Green et al.   JOURNAL OF IMMUNOLOGY

(1,3)- -Glucans Activate Both Dectin-1 and NLRP3 Inflammasome in Human Macrophages

(2010) P. Kankkunen et al.   JOURNAL OF IMMUNOLOGY

A new method to isolate microglia from adult mice and culture them for an extended period of time

(2010) Simon Moussaud et al.   JOURNAL OF NEUROSCIENCE METHODS

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

IRAK-M Regulates Chromatin Remodeling in Lung Macrophages during Experimental Sepsis

(2010) Kenneth Lyn-Kew et al.   PLoS One

Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses

(2010) M. Ritter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host-Detrimental Role of Esx-1-Mediated Inflammasome Activation in Mycobacterial Infection

(2010) Fredric Carlsson et al.   PLoS Pathogens

IL-1β Processing in Host Defense: Beyond the Inflammasomes

(2010) Mihai G. Netea et al.   PLoS Pathogens

Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia

(2009) Kayo Terada et al.   GLIA

Glucocorticoid receptor agonist compound K regulates dectin-1-dependent inflammatory signaling through inhibition of reactive oxygen species

(2009) Trinh Tat Cuong et al.   LIFE SCIENCES

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

The NLRP3 inflammasome: A sensor of immune danger signals

(2009) Suzanne L. Cassel et al.   SEMINARS IN IMMUNOLOGY

Mycobacterium tuberculosis Prevents Inflammasome Activation

(2008) Sharon S. Master et al.   Cell Host & Microbe

Central Nervous System Tuberculosis: Pathogenesis and Clinical Aspects

(2008) R. B. Rock et al.   CLINICAL MICROBIOLOGY REVIEWS

Monocyte-dependent oncostatin M and TNF-α synergize to stimulate unopposed matrix metalloproteinase-1/3 secretion from human lung fibroblasts in tuberculosis

(2008) Cecilia M. O'Kane et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammasomes: guardians of cytosolic sanctity

(2008) Mohamed Lamkanfi et al.   IMMUNOLOGICAL REVIEWS

Roles of Reactive Oxygen Species in CXCL8 and CCL2 Expression in Response to the 30-kDa Antigen of Mycobacterium tuberculosis

(2008) Hye-Mi Lee et al.   JOURNAL OF CLINICAL IMMUNOLOGY

The NALP3/Cryopyrin-Inflammasome Complex is Expressed in LPS-Induced Ocular Inflammation

(2008) José F. González-Benítez et al.   MEDIATORS OF INFLAMMATION

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY