Statins amplify TLR-induced responses in microglia via inhibition of cholesterol biosynthesis

Regulation of Innate Immune Responses in the Central Nervous System

(2011) Jeffrey J. Bajramovic   CNS & Neurological Disorders-Drug Targets

Simvastatin treatment in patients with relapsing-remitting multiple sclerosis receiving interferon beta 1a: a double-blind randomized controlled trial

(2010) Mansoureh Togha et al.   Multiple Sclerosis Journal

Atorvastatin Combined To Interferon to Verify the Efficacy (ACTIVE) in relapsing— remitting active multiple sclerosis patients: a longitudinal controlled trial of combination therapy

(2010) Roberta Lanzillo et al.   Multiple Sclerosis Journal

Statin Therapy Inhibits Remyelination in the Central Nervous System

(2009) Veronique E. Miron et al.   AMERICAN JOURNAL OF PATHOLOGY

Differential Expression of Adenosine A3 Receptors Controls Adenosine A2A Receptor-Mediated Inhibition of TLR Responses in Microglia

(2009) C. van der Putten et al.   JOURNAL OF IMMUNOLOGY

Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis

(2008) Ajaib S. Paintlia et al.   EXPERIMENTAL NEUROLOGY

Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis

(2008) Ajaib S. Paintlia et al.   GLIA

Negative Impact of Statins on Oligodendrocytes and Myelin Formation In Vitro and In Vivo

(2008) S. Klopfleisch et al.   JOURNAL OF NEUROSCIENCE

Combining beta interferon and atorvastatin may increase disease activity in multiple sclerosis

(2008) G. Birnbaum et al.   NEUROLOGY

Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression

(2008) Conrad P. Hodgkinson et al.   Pharmacogenetics and Genomics

Oral High-Dose Atorvastatin Treatment in Relapsing-Remitting Multiple Sclerosis

(2008) Friedemann Paul et al.   PLoS One

Statins enhance toll-like receptor 4-mediated cytokine gene expression in astrocytes: Implication of Rho proteins in negative feedback regulation

(2007) Gregory W. Konat et al.   JOURNAL OF NEUROSCIENCE RESEARCH