Inter-ethnic differences in genetic variants within the transmembrane protease, serine 6 (TMPRSS6) gene associated with iron status indicators: a systematic review with meta-analyses

The liver: conductor of systemic iron balance

(2013) D. Meynard et al.   BLOOD

Iron refractory iron deficiency anemia

(2013) L. De Falco et al.   HAEMATOLOGICA

Associations of common variants inHFEandTMPRSS6with iron parameters are independent of serum hepcidin in a general population: a replication study

(2013) Tessel E Galesloot et al.   JOURNAL OF MEDICAL GENETICS

Association of TMPRSS6 polymorphisms with ferritin, hemoglobin, and type 2 diabetes risk in a Chinese Han population

(2012) Wei Gan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia

(2012) Peng An et al.   HUMAN MOLECULAR GENETICS

Candidate Gene Sequencing of SLC11A2 and TMPRSS6 in a Family with Severe Anaemia: Common SNPs, Rare Haplotypes, No Causative Mutation

(2012) Anita Kloss-Brandstätter et al.   PLoS One

Associations between Single Nucleotide Polymorphisms in Iron-Related Genes and Iron Status in Multiethnic Populations

(2012) Christine E. McLaren et al.   PLoS One

Genetic Determinants for Body Iron Store and Type 2 Diabetes Risk in US Men and Women

(2012) Meian He et al.   PLoS One

A genetic risk factor for low serum ferritin levels in Danish blood donors

(2012) Erik Sørensen et al.   TRANSFUSION

TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals

(2011) A. Nai et al.   BLOOD

Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels

(2011) Irene Pichler et al.   HUMAN MOLECULAR GENETICS

Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations

(2011) M. Traglia et al.   JOURNAL OF MEDICAL GENETICS

Four variants in transferrin and HFE genes as potential markers of iron deficiency anaemia risk: an association study in menstruating women

(2011) Ruth Blanco-Rojo et al.   Nutrition & Metabolism

Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels

(2010) Konrad Oexle et al.   HUMAN MOLECULAR GENETICS

Role of Matriptase-2 (TMPRSS6) in Iron Metabolism

(2009) Pauline Lee   ACTA HAEMATOLOGICA

A genome-wide association analysis of serum iron concentrations

(2009) T. Tanaka et al.   BLOOD

Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels

(2009) John C Chambers et al.   NATURE GENETICS

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

(2009) Santhi K Ganesh et al.   NATURE GENETICS

Common variants in TMPRSS6 are associated with iron status and erythrocyte volume

(2009) Beben Benyamin et al.   NATURE GENETICS

The Genetic Structure and History of Africans and African Americans

(2009) S. A. Tishkoff et al.   SCIENCE

Iron-Refractory Iron Deficiency Anemia

(2009) Karin E. Finberg   SEMINARS IN HEMATOLOGY

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

(2008) A. R. Folgueras et al.   BLOOD

Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency

(2008) F. Guillem et al.   BLOOD

Worldwide population differentiation at disease-associated SNPs

(2008) Sean Myles et al.   BMC Medical Genomics

The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

(2008) Laura Silvestri et al.   Cell Metabolism

A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron

(2008) M. A. Melis et al.   HAEMATOLOGICA

Genotype, haplotype and copy-number variation in worldwide human populations

(2008) Mattias Jakobsson et al.   NATURE

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

(2008) Karin E Finberg et al.   NATURE GENETICS

The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

(2008) X. Du et al.   SCIENCE

Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation

(2008) J. Z. Li et al.   SCIENCE