Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels

Iron Toxicity in Diseases of Aging: Alzheimer's Disease, Parkinson's Disease and Atherosclerosis

(2017) Sandro Altamura et al.   JOURNAL OF ALZHEIMERS DISEASE

Proinflammatory state, hepcidin, and anemia in older persons

(2010) L. Ferrucci et al.   BLOOD

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Characterization of the Interaction between Diferric Transferrin and Transferrin Receptor 2 by Functional Assays and Atomic Force Microscopy

(2010) Katsuya Ikuta et al.   JOURNAL OF MOLECULAR BIOLOGY

Liver and Adipose Expression Associated SNPs Are Enriched for Association to Type 2 Diabetes

(2010) Hua Zhong et al.   PLoS Genetics

Genotype Imputation

(2009) Yun Li et al.   Annual Review of Genomics and Human Genetics

A genome-wide association analysis of serum iron concentrations

(2009) T. Tanaka et al.   BLOOD

Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications

(2009) I. Theurl et al.   BLOOD

Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis

(2009) A. J. Ramsay et al.   HAEMATOLOGICA

Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels

(2009) John C Chambers et al.   NATURE GENETICS

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

(2009) Santhi K Ganesh et al.   NATURE GENETICS

Common variants in TMPRSS6 are associated with iron status and erythrocyte volume

(2009) Beben Benyamin et al.   NATURE GENETICS

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

(2009) Nicole Soranzo et al.   NATURE GENETICS

Genetic mechanisms and modifying factors in hereditary hemochromatosis

(2009) Günter Weiss   Nature Reviews Gastroenterology & Hepatology

Phosphodiesterase 8B Gene Variants Are Associated with Serum TSH Levels and Thyroid Function

(2008) Lisette Arnaud-Lopez et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Variants in TF and HFE Explain ∼40% of Genetic Variation in Serum-Transferrin Levels

(2008) Beben Benyamin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

(2008) A. R. Folgueras et al.   BLOOD

Immunoassay for human serum hepcidin

(2008) T. Ganz et al.   BLOOD

Fine Tuning of Hepcidin Expression by Positive and Negative Regulators

(2008) Martina U. Muckenthaler   Cell Metabolism

The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

(2008) Laura Silvestri et al.   Cell Metabolism

The role of correction of anaemia in patients with congestive heart failure: A short review

(2008) Donald S. Silverberg et al.   EUROPEAN JOURNAL OF HEART FAILURE

A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron

(2008) M. A. Melis et al.   HAEMATOLOGICA

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

(2008) Karin E Finberg et al.   NATURE GENETICS

Advances in Quantitative Hepcidin Measurements by Time-of-Flight Mass Spectrometry

(2008) Dorine W. Swinkels et al.   PLoS One

Differential Allelic Expression in the Human Genome: A Robust Approach To Identify Genetic and Epigenetic Cis-Acting Mechanisms Regulating Gene Expression

(2008) David Serre et al.   PLoS Genetics

Screening for hemochromatosis by measuring ferritin levels: a more effective approach

(2007) J. Waalen et al.   BLOOD

Estimates of Genetic and Environmental Contribution to 43 Quantitative Traits Support Sharing of a Homogeneous Environment in an Isolated Population from South Tyrol, Italy

(2007) Fabio Marroni et al.   HUMAN HEREDITY

Regulation of iron acquisition and storage: consequences for iron-linked disorders

(2007) Ivana De Domenico et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY