Noninvasive, neuron-specific gene therapy can be facilitated by focused ultrasound and recombinant adeno-associated virus

In vivo performance of a microfabricated catheter for intraparenchymal delivery

(2014) Martin L. Brady et al.   JOURNAL OF NEUROSCIENCE METHODS

A next step in adeno-associated virus-mediated gene therapy for neurological diseases: regulation and targeting

(2013) Abdelwahed Chtarto et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Blood–brain barrier structure and function and the challenges for CNS drug delivery

(2013) N. Joan Abbott   JOURNAL OF INHERITED METABOLIC DISEASE

Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients

(2013) R. T. Bartus et al.   NEUROLOGY

Noninvasive and Targeted Gene Delivery into the Brain Using Microbubble-Facilitated Focused Ultrasound

(2013) Po-Hung Hsu et al.   PLoS One

Radially Branched Deployment for More Efficient Cell Transplantation at the Scale of the Human Brain

(2013) Matthew T. Silvestrini et al.   STEREOTACTIC AND FUNCTIONAL NEUROSURGERY

Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening

(2013) Angelika Alonso et al.   Molecular Therapy-Nucleic Acids

Temporary Disruption of the Blood-Brain Barrier by Use of Ultrasound and Microbubbles: Safety and Efficacy Evaluation in Rhesus Macaques

(2012) N. McDannold et al.   CANCER RESEARCH

Safety Study of Adeno-Associated Virus Serotype 2-Mediated Human Acid Sphingomyelinase Expression in the Nonhuman Primate Brain

(2012) Ernesto A. Salegio et al.   HUMAN GENE THERAPY

Targeted Delivery of Self-Complementary Adeno-Associated Virus Serotype 9 to the Brain, Using Magnetic Resonance Imaging-Guided Focused Ultrasound

(2012) Emmanuel Thévenot et al.   HUMAN GENE THERAPY

Ultrasound-mediated blood‐brain/blood-tumor barrier disruption improves outcomes with trastuzumab in a breast cancer brain metastasis model

(2012) Eun-Joo Park et al.   JOURNAL OF CONTROLLED RELEASE

Pathogenesis of Parkinson's disease

(2012) Etienne C. Hirsch et al.   MOVEMENT DISORDERS

Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood–brain barrier using focused ultrasound and microbubbles

(2012) Babak Baseri et al.   PHYSICS IN MEDICINE AND BIOLOGY

A novel metal artifact reducing method for cone-beam CT based on three approximately orthogonal projections

(2012) Qingli Wang et al.   PHYSICS IN MEDICINE AND BIOLOGY

Feasibility of noninvasive cavitation-guided blood-brain barrier opening using focused ultrasound and microbubbles in nonhuman primates

(2011) Fabrice Marquet et al.   APPLIED PHYSICS LETTERS

The mechanism of interaction between focused ultrasound and microbubbles in blood-brain barrier opening in mice

(2011) Yao-Sheng Tung et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial

(2011) Peter A LeWitt et al.   LANCET NEUROLOGY

Noninvasive and localized neuronal delivery using short ultrasonic pulses and microbubbles

(2011) J. J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Permeability assessment of the focused ultrasound-induced blood–brain barrier opening using dynamic contrast-enhanced MRI

(2010) F Vlachos et al.   PHYSICS IN MEDICINE AND BIOLOGY

Tests to assess motor phenotype in mice: a user's guide

(2009) Simon P. Brooks et al.   NATURE REVIEWS NEUROSCIENCE

Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

(2009) C. W. Christine et al.   NEUROLOGY