Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver
出版年份 2010 全文链接
标题
Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver
作者
关键词
-
出版物
GENE THERAPY
Volume 18, Issue 4, Pages 403-410
出版商
Springer Nature
发表日期
2010-12-09
DOI
10.1038/gt.2010.157
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mammalian microRNAs predominantly act to decrease target mRNA levels
- (2010) Huili Guo et al. NATURE
- High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency
- (2009) E Ayuso et al. GENE THERAPY
- A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery
- (2009) C-Y Yu et al. GENE THERAPY
- Adeno-Associated Virus-Mediated Gene Transfer to Nonhuman Primate Liver Can Elicit Destructive Transgene-Specific T Cell Responses
- (2009) Guangping Gao et al. HUMAN GENE THERAPY
- Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial
- (2009) Albert M Maguire et al. LANCET
- A Preclinical Animal Model to Assess the Effect of Pre-existing Immunity on AAV-mediated Gene Transfer
- (2009) Hua Li et al. MOLECULAR THERAPY
- Gene Therapy for Leber's Congenital Amaurosis is Safe and Effective Through 1.5 Years After Vector Administration
- (2009) Francesca Simonelli et al. MOLECULAR THERAPY
- Tolerance Induction to Cytoplasmic β-Galactosidase by Hepatic AAV Gene Transfer — Implications for Antigen Presentation and Immunotoxicity
- (2009) Ashley T. Martino et al. PLoS One
- A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection
- (2009) L. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct immune responses to transgene products from rAAV1 and rAAV8 vectors
- (2009) Y. Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy
- (2009) M. L. Brantly et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene Therapy Using Adeno-Associated Virus Vectors
- (2008) S. Daya et al. CLINICAL MICROBIOLOGY REVIEWS
- Construction and analysis of compact muscle-specific promoters for AAV vectors
- (2008) B Wang et al. GENE THERAPY
- Adeno-Associated Virus (AAV) Serotype 9 Provides Global Cardiac Gene Transfer Superior to AAV1, AAV6, AAV7, and AAV8 in the Mouse and Rat
- (2008) Lawrence T. Bish et al. HUMAN GENE THERAPY
- Treatment of Leber Congenital Amaurosis Due to RPE65 Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial
- (2008) William W. Hauswirth et al. HUMAN GENE THERAPY
- miR-122, a paradigm for the role of microRNAs in the liver
- (2008) Muriel Girard et al. JOURNAL OF HEPATOLOGY
- AAV-mediated TRAIL gene expression driven by hTERT promoter suppressed human hepatocellular carcinoma growth in mice
- (2008) Ying Zhang et al. LIFE SCIENCES
- A Single Intravenous Injection of Adeno-associated Virus Serotype-9 Leads to Whole Body Skeletal Muscle Transduction in Dogs
- (2008) Yongping Yue et al. MOLECULAR THERAPY
- Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis
- (2008) Albert M. Maguire et al. NEW ENGLAND JOURNAL OF MEDICINE
- Advances in MicroRNAs: Implications for Gene Therapists
- (2007) Rebecca T. Marquez et al. HUMAN GENE THERAPY
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