Embedding sustainable practices into pharmaceutical R&D: what are the challenges?

The evolution of life cycle assessment in pharmaceutical and chemical applications – a perspective

(2014) Concepción Jiménez-González et al.   GREEN CHEMISTRY

Clinical development success rates for investigational drugs

(2014) Michael Hay et al.   NATURE BIOTECHNOLOGY

Development of GSK's reagent guides – embedding sustainability into reagent selection

(2013) Joseph P. Adams et al.   GREEN CHEMISTRY

Lead-Oriented Synthesis: A New Opportunity for Synthetic Chemistry

(2012) Alan Nadin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Practical purification of hydrophilic fragments and lead/drug-like molecules by reverse phase flash chromatography: tips, tricks and contemporary developments

(2012) Andrew N. Hobbs et al.   DRUG DISCOVERY TODAY

A convenient guide to help select replacement solvents for dichloromethane in chromatography

(2012) Joshua P. Taygerly et al.   GREEN CHEMISTRY

Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide

(2012) Donna S. MacMillan et al.   GREEN CHEMISTRY

Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry

(2011) Richard K. Henderson et al.   GREEN CHEMISTRY

Using the Right Green Yardstick: Why Process Mass Intensity Is Used in the Pharmaceutical Industry To Drive More Sustainable Processes

(2011) Concepcion Jimenez-Gonzalez et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT