Calcilytics: antagonists of the calcium-sensing receptor for the treatment of osteoporosis

Pharmacological manipulation of calcium-sensing receptor: Prospect as anabolic therapy for postmenopausal osteoporosis

(2015) R. Trivedi et al.   DRUGS OF THE FUTURE

The Calcium-Sensing Receptor: A Molecular Perspective

(2011) Aaron L. Magno et al.   ENDOCRINE REVIEWS

New aminopropandiol derivatives as orally available and short-acting calcium-sensing receptor antagonists

(2010) Yuko Shinagawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Penta-substituted benzimidazoles as potent antagonists of the calcium-sensing receptor (CaSR-antagonists)

(2010) Marc Gerspacher et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery Tactics To Mitigate Toxicity Risks Due to Reactive Metabolite Formation with 2-(2-Hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one Derivatives, Potent Calcium-Sensing Receptor Antagonists and Clinical Candidate(s) for the Treatment of Osteoporosis

(2010) Amit S. Kalgutkar et al.   CHEMICAL RESEARCH IN TOXICOLOGY

1-Alkyl-4-phenyl-6-alkoxy-1H-quinazolin-2-ones: A Novel Series of Potent Calcium-Sensing Receptor Antagonists

(2010) Leo Widler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Emerging Targets in Osteoporosis Disease Modification

(2010) John G. Allen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Diverse roles of extracellular calcium-sensing receptor in the central nervous system

(2010) Sanghamitra Bandyopadhyay et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Does osteocytic SOST suppression mediate PTH bone anabolism?

(2010) Ina Kramer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Metabolism-Guided Design of Short-Acting Calcium-Sensing Receptor Antagonists

(2010) James A. Southers et al.   ACS Medicinal Chemistry Letters

The Functions and Roles of the Extracellular Ca2+–Sensing Receptor along the Gastrointestinal Tract

(2009) John P. Geibel et al.   Annual Review of Physiology

Short-acting 5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as orally-active calcium-sensing receptor antagonists

(2009) Mary T. Didiuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The discovery of novel calcium sensing receptor negative allosteric modulators

(2009) Gayatri Balan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Rapid and robust response of biochemical markers of bone formation to teriparatide therapy

(2009) Sarah J. Glover et al.   BONE

An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation

(2009) Sanjay Kumar et al.   BONE

Antagonists of the Calcium Receptor. 2. Amino Alcohol-Based Parathyroid Hormone Secretagogues

(2009) Robert W. Marquis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery and Structure−Activity Relationships of Trisubstituted Pyrimidines/Pyridines as Novel Calcium-Sensing Receptor Antagonists

(2009) Wu Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antagonists of the Calcium Receptor I. Amino Alcohol-Based Parathyroid Hormone Secretagogues

(2009) Robert W. Marquis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Application of the National Osteoporosis Foundation Guidelines to postmenopausal women and men: the Framingham Osteoporosis Study

(2009) S. D. Berry et al.   OSTEOPOROSIS INTERNATIONAL

Clinical update on teriparatide

(2009) Elizabeth File et al.   Current Rheumatology Reports

Teriparatide in the treatment of osteoporosis

(2008) J. Stroup et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Studies on the mechanisms of the skeletal anabolic action of endogenous and exogenous parathyroid hormone

(2008) David Goltzman   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Recent Updates on the Calcium-Sensing Receptor as a Drug Target

(2008) Ritu Trivedi et al.   CURRENT MEDICINAL CHEMISTRY

Teriparatide

(2008) Stephanie K A Blick et al.   DRUGS

Cinacalcet: pharmacological and clinical aspects

(2008) Piergiorgio Messa et al.   Expert Opinion on Drug Metabolism & Toxicology

On the Interpretation of Rat Carcinogenicity Studies for Human PTH(1-34) and Human PTH(1-84)

(2008) Armen H Tashjian et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Improved model building and assessment of the Calcium-sensing receptor transmembrane domain

(2007) Lintao Bu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS