Mitochondrial dysfunction in non-alcoholic fatty liver disease and insulin resistance: Cause or consequence?

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome

(2013) Derrick M. Van Rooyen et al.   JOURNAL OF HEPATOLOGY

Expression and roles of steroidogenic acute regulatory (StAR) protein in ‘non-classical’, extra-adrenal and extra-gonadal cells and tissues

(2013) Eli Anuka et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Adipose-Specific Deletion of TFAM Increases Mitochondrial Oxidation and Protects Mice against Obesity and Insulin Resistance

(2012) Cecile Vernochet et al.   Cell Metabolism

Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice

(2012) W. Keung et al.   DIABETES

Disruption of the histidine triad nucleotide-binding hint2 gene in mice affects glycemic control and mitochondrial function

(2012) Juliette Martin et al.   HEPATOLOGY

Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis

(2012) Claudia von Montfort et al.   JOURNAL OF HEPATOLOGY

Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity

(2012) S. Timmers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training

(2011) Christina Yfanti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Metabolic Therapy: Lessons from Liver Diseases

(2011) Carmen Garcia-Ruiz et al.   CURRENT PHARMACEUTICAL DESIGN

Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis

(2011) Anabela P. Rolo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial dysfunction in patients with primary congenital insulin resistance

(2011) Alison Sleigh et al.   JOURNAL OF CLINICAL INVESTIGATION

Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study

(2011) Chi Pang Wen et al.   LANCET

Oxidation of Hepatic Carnitine Palmitoyl Transferase-I (CPT-I) Impairs Fatty Acid Beta-Oxidation in Rats Fed a Methionine-Choline Deficient Diet

(2011) Gaetano Serviddio et al.   PLoS One

Concentration-dependent Dual Effects of Hydrogen Peroxide on Insulin Signal Transduction in H4IIEC Hepatocytes

(2011) Satoshi Iwakami et al.   PLoS One

Antioxidant Supplementation during Exercise Training

(2011) Tina-Tinkara Peternelj et al.   SPORTS MEDICINE

Mapping Insulin/GLUT4 Circuitry

(2011) Alexander F. Rowland et al.   TRAFFIC

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species

(2010) Andreas Daiber   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity

(2010) Jia Li et al.   Cell Metabolism

Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption

(2010) J. R. Ussher et al.   DIABETES

Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation

(2010) Josep M. Orellana-Gavaldà et al.   HEPATOLOGY

Effects of a high-fat diet on energy metabolism and ROS production in rat liver

(2010) Guillaume Vial et al.   JOURNAL OF HEPATOLOGY

Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis

(2010) Arun J. Sanyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Changes in Hepatic Gene Expression upon Oral Administration of Taurine-Conjugated Ursodeoxycholic Acid in ob/ob Mice

(2010) Jae-Seong Yang et al.   PLoS One

Insulin signaling meets mitochondria in metabolism

(2010) Zhiyong Cheng et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Exercise therapy in Type 2 diabetes

(2009) Stephan F. E. Praet et al.   ACTA DIABETOLOGICA

Mitochondrial Glutathione, a Key Survival Antioxidant

(2009) Montserrat Marí et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Control of Liver Function in Health and Disease

(2009) Montserrat Marí et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of fatty acid uptake and fatty acid β-oxidation in mediating insulin resistance in heart and skeletal muscle

(2009) Liyan Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism

Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria

(2009) Seiji Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homocysteine Supplementation Attenuates the Unfolded Protein Response in a Murine Nutritional Model of Steatohepatitis

(2009) Anne S. Henkel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH

(2009) Francisco Caballero et al.   JOURNAL OF HEPATOLOGY

Controlling metabolism and cell death: At the heart of mitochondrial calcium signalling

(2009) Marta Murgia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Insulin resistance is a cellular antioxidant defense mechanism

(2009) K. L. Hoehn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maturation of Iron-Sulfur Proteins in Eukaryotes: Mechanisms, Connected Processes, and Diseases

(2008) Roland Lill et al.   Annual Review of Biochemistry

The biological relevance and measurement of plasma markers of oxidative stress in diabetes and cardiovascular disease

(2008) Jeffrey W. Stephens et al.   ATHEROSCLEROSIS

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

The versatility of mitochondrial calcium signals: From stimulation of cell metabolism to induction of cell death

(2008) Alessandro Rimessi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The malonyl CoA axis as a potential target for treating ischaemic heart disease

(2008) J. R. Ussher et al.   CARDIOVASCULAR RESEARCH

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

How Insulin Receptor Substrate Proteins Regulate the Metabolic Capacity of the Liver - Implications for Health and Disease

(2008) Louise Fritsche et al.   CURRENT MEDICINAL CHEMISTRY

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

(2008) E. Phielix et al.   DIABETES

High-fat diets cause insulin resistance despite an increase in muscle mitochondria

(2008) C. R. Hancock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rat liver mitochondrial carnitine palmitoyltransferase-I, hepatic carnitine, and malonyl-CoA: Effect of starvation

(2008) Janos Kerner et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease

(2007) Puneet Puri et al.   GASTROENTEROLOGY

Homozygous carnitine palmitoyltransferase 1b (muscle isoform) deficiency is lethal in the mouse

(2007) Shaonin Ji et al.   MOLECULAR GENETICS AND METABOLISM