期刊
FOOD RESEARCH INTERNATIONAL
卷 49, 期 1, 页码 153-160出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.foodres.2012.07.052
关键词
Myrciaria spp.; Jaboticaba; Obesity; Insulin resistance; HDL-cholesterol
资金
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
Jaboticaba (Myrciaria spp.) is a Brazilian fruit with high concentrations of anthocyanins in the peel which have shown antioxidant effects and possible benefits on obesity and insulin resistance. The objective of this study was to evaluate the effect of freeze-dried jaboticaba peel (FJP) added to high-fat diet on the development of obesity and insulin resistance. Sprague-Dawley rats were fed control diet, high-fat diet (HF) and HF diets added with 1.2 and 4% of FJP. Energy intake, weight gain, body composition, serum glucose, and lipid and hormonal profiles were determined. Glucose tolerance, insulin tolerance and HOMA-IR index were determined. The consumption of 1.2 and 4% FJP reduced serum insulin (47.57 and 52%, respectively) and HOMA-IR (40,54 and 48%, respectively). In addition, 2% FJP showed to increase HDL-cholesterol levels by 41.65% compared to HF control. Other parameters showed no significant changes. In conclusion, the consumption of FJP showed to increase HDL-cholesterol and improve insulin resistance in experimental animals. (C) 2012 Elsevier Ltd. All rights reserved.
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