Article
Food Science & Technology
Shuai Yu, Hongmei Li, Taihua Cui, Mingxun Cui, Chunxiang Piao, Shitong Wang, Ming Ju, Xin Liu, Guanghong Zhou, Hongyan Xu, Guanhao Li
Summary: Onion peel extract has potential anti-obesity effects by reducing lipid accumulation, lowering blood lipid levels, and decreasing body weight. Further research is needed to develop natural anti-obesity foods and supplements based on onion peel extract.
Article
Cell Biology
Francesca Molinari, Alessandra Feraco, Simone Mirabilii, Serena Saladini, Luigi Sansone, Enza Vernucci, Giada Tomaselli, Vincenzo Marzolla, Dante Rotili, Matteo A. Russo, Maria Rosaria Ricciardi, Agostino Tafuri, Antonello Mai, Massimiliano Caprio, Marco Tafani, Andrea Armani
Summary: The inhibition of SIRT5 stimulates brown adipogenesis in vitro, promoting the expression of brown adipocyte and mitochondrial markers and increasing lipolysis. This approach shows potential as a strategy to target obesity and type 2 diabetes by activating brown adipose tissue.
Article
Chemistry, Medicinal
Fernanda Malanconi Thomaz, Jussara de Jesus Simao, Viviane Simoes da Silva, Meira Maria Forcelini Machado, Lila Missae Oyama, Eliane Beraldi Ribeiro, Maria Isabel Cardoso Alonso Vale, Monica Marques Telles
Summary: The study found that Ginkgo biloba extract (GbE) can modulate adipocyte differentiation, increasing lipid content and gene expression of major adipogenesis markers. GbE can modify key proteins involved in the differentiation process and accelerate the expression of mature adipocyte proteins.
Article
Biochemistry & Molecular Biology
Zexiu Qi, Jie Lin, Ruichang Gao, Weize Wu, Yan Zhang, Xinyuan Wei, Xiang Xiao, Huili Wang, Ye Peng, John M. Clark, Yeonhwa Park, Quancai Sun
Summary: This study investigates the molecular mechanisms of deltamethrin induced fat accumulation in murine adipocytes. The results show that deltamethrin promotes adipogenesis and involves multiple key functional groups regulating adipogenesis.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2022)
Article
Medicine, Research & Experimental
Benjarat Janson, Janjira Prasomthong, Wachirawadee Malakul, Tantip Boonsong, Sakara Tunsophon
Summary: This study demonstrated that roselle extract can reduce body weight, food intake, lipid profiles, inflammatory cytokines, lipid peroxidation, serum leptin, insulin, and duodenal glucose absorption, while significantly increasing glucose uptake of adipose tissue and muscle compared to a high-fat diet group. Roselle can prevent lipid accumulation by suppressing differentiation of 3T3-L1 adipocyte through downregulating adipogenic gene expression, providing an alternative approach for preventing obesity-related insulin resistance.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Nutrition & Dietetics
So-Won Heo, Kyung-Sook Chung, Young-Seo Yoon, Soo-Yeon Kim, Hye-Shin Ahn, Yu-Kyong Shin, Sun-Hee Lee, Kyung-Tae Lee
Summary: Obesity is a global threat to public health, leading to diseases such as type 2 diabetes and non-alcoholic fatty liver disease. In this study, we found that a herbal extract called EECM has anti-obesity effects by inhibiting adipogenesis and lipogenesis and regulating adipogenic hormones. EECM was also effective in reducing body weight gain, body fat accumulation, and adipocyte and lipid accumulation in mice. It induced thermogenic factors in brown adipose tissue and restored gut microbiome composition. EECM may serve as a promising therapeutic agent for preventing obesity.
Article
Food Science & Technology
Wenrui Liu, Lihua Wang, Jie Zhang
Summary: Peanut shells, as agricultural waste, contain luteolin (LUT) which has anti-obesity properties. The study found that the extract from peanut shells can inhibit adipogenesis, accelerate lipolysis, and promote lipid browning, making it a potential dietary supplement for weight management.
Article
Biochemistry & Molecular Biology
Yun-Mi Kang, Hyun-Ae Kang, Divina C. Cominguez, Su-Hyun Kim, Hyo-Jin An
Summary: Papain exerts anti-obesity effects by regulating levels of adipogenic factors involved in lipid metabolism and inflammation in HFD-induced mice and 3T3-L1 preadipocytes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nutrition & Dietetics
Ge Chen, Ge Wang, Weidong Xu, Ying Xiao, Ye Peng
Summary: Overall, this study suggests that chlorantraniliprole-induced lipogenesis is mediated through a whole-gene transcriptome response. Several key genes involved in adipocyte differentiation and lipogenesis were identified, providing further insight into the potential mechanisms underlying chlorantraniliprole-induced adipogenesis.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Multidisciplinary
Xionggao Han, Sun-Il Choi, Xiao Men, Se-Jeong Lee, Heegu Jin, Hyun-Ji Oh, Eunjin Kim, Jongwook Kim, Boo-Yong Lee, Ok-Hwan Lee
Summary: The study evaluated the anti-obesity effect of ESETM extract and found that it can inhibit adipogenesis and lipid accumulation, reducing weight change. The results suggest that ESETM may regulate weight through adipogenesis, lipogenesis, lipolysis, and thermogenesis pathways.
APPLIED SCIENCES-BASEL
(2022)
Article
Nutrition & Dietetics
Xianfeng Deng, Bi Chen, Qin Luo, Xingru Zao, Haizhe Liu, Yongqiang Li
Summary: Hulless barley polyphenol (HBP) extract has the potential to inhibit obesity-related enzymes, prevent adipocyte differentiation, and attenuate adipogenesis, making it beneficial in preventing obesity.
FRONTIERS IN NUTRITION
(2022)
Article
Pharmacology & Pharmacy
Chaiwat Monmai, Jin-Suk Kim, Hyun Bo Sim, Doh-Won Yun, Sung-Dug Oh, Eui-Shik Rha, Jong-Jin Kim, So-Hyeon Baek
Summary: This study evaluated the effects of extracts from transgenic rice on inhibiting adipogenesis and anti-inflammatory activity. The results showed that the extracts significantly reduced lipid accumulation in cells and inhibited the expression of adipogenesis-related mRNA and inflammation-related factors. Therefore, transgenic rice may have potential as an obesity-reducing and/or -preventing agent.
Article
Agriculture, Multidisciplinary
Md Shamim Rahman, Inseok Kang, Youri Lee, Md Ahasun Habib, Byeong Jo Choi, Jong Soon Kang, Doo-Sang Park, Yong-Sik Kim
Summary: The study demonstrates the role of Bifidobacterium longum subsp. infantis YB0411 in inhibiting adipogenesis by reducing triglyceride accumulation and related gene expression, lowering levels of autophagic markers, and exerting anti-obesity effects through AMP-activated protein kinase. YB supplementation also significantly reduced body weight and fat accretion in mice with high-fat-diet-induced obesity.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Biotechnology & Applied Microbiology
Chul Sang Lee, Mi Hyun Park, Byoung Kook Kim, Sae Hun Kim
Summary: Obesity is a major cause of metabolic diseases, and inhibiting adipogenic differentiation can prevent and suppress obesity. Oral administration of Lactobacillus strains can improve serum lipid profile and normalize gut microbiota, effectively preventing obesity and improving metabolic health.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2021)
Article
Chemistry, Multidisciplinary
Soo-Jeung Park, Minhee Lee, Ki-Young Kim, Su Shin, Min-Woo Choi, Eun-Jin Hong, Jeongmin Lee
Summary: This study investigated the anti-obesity effect of the Trapa japonica Flerov extract (TJ) in differentiated 3T3-L1 adipocytes. The results showed that TJ reduced lipid accumulation by promoting lipolysis and inhibiting adipogenesis and lipogenesis. The component ellagic acid in TJ might contribute to its effectiveness.
APPLIED SCIENCES-BASEL
(2022)
Article
Food Science & Technology
Hyun Ju Do, Ji Hyung Chung, Ji Won Hwang, Oh Yoen Kim, Jae-Yeon Lee, Min-Jeong Shin
FOOD AND CHEMICAL TOXICOLOGY
(2015)
Article
Nutrition & Dietetics
Hye-Kyung Chung, Yoonsu Cho, Hyun Ju Do, Kyungmi Oh, Woo-Keun Seo, Min-Jeong Shin
NUTRITION RESEARCH
(2015)
Article
Food Science & Technology
Ji Won Hwang, Hyun Ju Do, Oh Yoen Kim, Ji Hyung Chung, Jae-Yeon Lee, Young Shik Park, Kyo Yeol Hwang, Su-Il Seong, Min-Jeong Shin
JOURNAL OF FUNCTIONAL FOODS
(2015)
Article
Oncology
Eunjung Ryu, Seung Yun Yim, Hyun Ju Do, Jae-Young Lim, Eun Joo Yang, Min-Jeong Shin, Seung-Min Lee
SUPPORTIVE CARE IN CANCER
(2016)
Article
Cell Biology
Hyun Ju Do, Tae Woo Oh, Ju Hye Yang, Kwang Il Park, Jin Yeul Ma
MEDIATORS OF INFLAMMATION
(2017)
Article
Plant Sciences
Ju-Hye Yang, Hyun Ju Do, Esther Lee, Nam-Hui Yim, Won-Kyung Cho, Kwang-Il Park, Jin Yeul Ma
JOURNAL OF ETHNOPHARMACOLOGY
(2018)
Article
Neurosciences
Soo Jin Yang, Hyun Ju Do, Youngae Jung, Geum-Sook Hwang, Min-Jeong Shin
NUTRITIONAL NEUROSCIENCE
(2019)
Article
Multidisciplinary Sciences
Jiyoung Moon, Hyun Ju Do, Yoonsu Cho, Min-Jeong Shin
Article
Pharmacology & Pharmacy
Kyungho Kim, Hyun Ju Do, Tae Woo Oh, Kwang-Youn Kim, Tae Hoon Kim, Jin Yel Ma, Kwang-Il Park
FRONTIERS IN PHARMACOLOGY
(2019)
Article
Integrative & Complementary Medicine
Hyun Ju Do, Yeo Jin Hwang, Hye Jin Yang, Kwang Il Park
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2019)
Article
Cell Biology
Hyun Ju Do, Tae Woo Oh, Kwang-Il Park
MEDIATORS OF INFLAMMATION
(2019)
Article
Biochemistry & Molecular Biology
Su Youn Baek, Eun Hye Lee, Tae Woo Oh, Hyun Ju Do, Kwang-Youn Kim, Kwang-Il Park, Young Woo Kim
Article
Biochemistry & Molecular Biology
Tae Woo Oh, Kwang-Youn Kim, Hyun Ju Do, Young-Woo Kim, Kwang-Il Park
MOLECULAR & CELLULAR TOXICOLOGY
(2020)
Article
Plant Sciences
Tae Woo Oh, Hyun Ju Do, Jae-Han Jeon, Kyungho Kim
Summary: The study demonstrated that quercitrin has inhibitory effects on platelet activity, can block thrombus formation, reduce infarct volume in stroke, and does not prolong bleeding time.
Article
Endocrinology & Metabolism
Hyun Ju Do, Youn Sue Lee, Min Jin Ha, Yoonsu Cho, Hana Yi, Yu-Jin Hwang, Geum-Sook Hwang, Min-Jeong Shin